Awareness of, willingness to use, and experiences with Pre-exposure prophylaxis among youth in Nigeria.


Journal

BMC health services research
ISSN: 1472-6963
Titre abrégé: BMC Health Serv Res
Pays: England
ID NLM: 101088677

Informations de publication

Date de publication:
27 Sep 2024
Historique:
received: 25 02 2023
accepted: 19 08 2024
medline: 28 9 2024
pubmed: 28 9 2024
entrez: 28 9 2024
Statut: epublish

Résumé

Youth (ages 14-24) in Nigeria have disproportionately high rates of new HIV infection. Pre-exposure prophylaxis could substantially reduce new infections among youth but has not been scaled up. This cross-sectional study aimed to assess Pre-exposure prophylaxis awareness, willingness to use, and prior use of Pre-exposure prophylaxis among youth in Nigeria. This is a secondary analysis of cross-sectional data from a quasi-experimental pilot study (clinical trial NCT04070287). The analysis focused on Pre-exposure prophylaxis awareness, willingness to use, and prior use among 324 youth recruited between September 2019 to March 2020. Descriptive statistics were calculated as frequencies and percentages for categorical variables and means and standard deviations for continuous variables. Of the 324 participants, the mean age and standard deviation were 21.17 (± 2.20) years. The majority were 20-24 years old (75.9%) and male (57.7%). Only 30.7% used condoms consistently over three months. Regarding Pre-exposure prophylaxis awareness and willingness, 62.6% had never heard of Pre-exposure prophylaxis, and 158 (50.1%) reported willingness to use Pre-exposure prophylaxis. Only 10 (3.2%) reported having used Pre-exposure prophylaxis. Nigerian youth have low awareness of and prior use of Pre-exposure prophylaxis. Given the gap between prior use and willingness to use Pre-exposure prophylaxis, our findings suggest missed opportunities to prevent new HIV infections among youth in Nigeria. Efforts to increase awareness and uptake of Pre-exposure prophylaxis among this population should consider youth-led Pre-exposure prophylaxis outreach efforts and effectively communicate the benefits of Pre-exposure prophylaxis to this population. NCT04070287, the Date of registration of the trial is 20-07-2019.

Sections du résumé

BACKGROUND BACKGROUND
Youth (ages 14-24) in Nigeria have disproportionately high rates of new HIV infection. Pre-exposure prophylaxis could substantially reduce new infections among youth but has not been scaled up. This cross-sectional study aimed to assess Pre-exposure prophylaxis awareness, willingness to use, and prior use of Pre-exposure prophylaxis among youth in Nigeria.
METHODS METHODS
This is a secondary analysis of cross-sectional data from a quasi-experimental pilot study (clinical trial NCT04070287). The analysis focused on Pre-exposure prophylaxis awareness, willingness to use, and prior use among 324 youth recruited between September 2019 to March 2020. Descriptive statistics were calculated as frequencies and percentages for categorical variables and means and standard deviations for continuous variables.
RESULTS RESULTS
Of the 324 participants, the mean age and standard deviation were 21.17 (± 2.20) years. The majority were 20-24 years old (75.9%) and male (57.7%). Only 30.7% used condoms consistently over three months. Regarding Pre-exposure prophylaxis awareness and willingness, 62.6% had never heard of Pre-exposure prophylaxis, and 158 (50.1%) reported willingness to use Pre-exposure prophylaxis. Only 10 (3.2%) reported having used Pre-exposure prophylaxis.
CONCLUSION CONCLUSIONS
Nigerian youth have low awareness of and prior use of Pre-exposure prophylaxis. Given the gap between prior use and willingness to use Pre-exposure prophylaxis, our findings suggest missed opportunities to prevent new HIV infections among youth in Nigeria. Efforts to increase awareness and uptake of Pre-exposure prophylaxis among this population should consider youth-led Pre-exposure prophylaxis outreach efforts and effectively communicate the benefits of Pre-exposure prophylaxis to this population.
TRIAL REGISTRATION BACKGROUND
NCT04070287, the Date of registration of the trial is 20-07-2019.

Identifiants

pubmed: 39334111
doi: 10.1186/s12913-024-11459-1
pii: 10.1186/s12913-024-11459-1
doi:

Substances chimiques

Anti-HIV Agents 0

Banques de données

ClinicalTrials.gov
['NCT04070287']

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1128

Subventions

Organisme : Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
ID : UG3HD096929
Organisme : National Institute of Allergy and Infectious Disease (NIAID)
ID : T32AI007001

Informations de copyright

© 2024. The Author(s).

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Auteurs

Titilola Gbaja-Biamila (T)

Washington University in St Louis, St Louis, USA. g.titilola@wustl.edu.
Nigerian Institute of Medical Research, Lagos, Nigeria. g.titilola@wustl.edu.

Chisom Obiezu-Umeh (C)

Northwestern University, Chicago, USA.

Ucheoma Nwaozuru (U)

Wake Forest School of Medicine, Winston-Salem, USA.

Nora E Rosenberg (NE)

University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Mesoma Igbokwe (M)

Rochester General Hospital, New York, USA.

David Oladele (D)

Nigerian Institute of Medical Research, Lagos, Nigeria.

Adesola Z Musa (AZ)

Nigerian Institute of Medical Research, Lagos, Nigeria.

Ifeoma Idigbe (I)

Nigerian Institute of Medical Research, Lagos, Nigeria.

Donaldson Conserve (D)

George Washington University, Washington, USA.

Suzanne Day (S)

University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Kadija Tahlil (K)

University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Jason Ong (J)

Monash University, Melbourne, Australia.
London School of Hygiene & Tropical Medicine, London, UK.

Kathryn Muessig (K)

Florida State University, Tallahassee, USA.

Susan Nkengasong (S)

London School of Hygiene & Tropical Medicine, London, UK.

Hong Xian (H)

Saint Louis University, St Louis, USA.

Joseph D Tucker (JD)

University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
London School of Hygiene & Tropical Medicine, London, UK.

Oliver Ezechi (O)

Nigerian Institute of Medical Research, Lagos, Nigeria.

Juliet Iwelunmor (J)

Washington University in St Louis, St Louis, USA.

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