Alterations of Liver Morphology in Senescent Rats.

Animals Liver / metabolism Rats Aging Male Hepatocytes / metabolism Cell Nucleus / metabolism Collagen Type I / metabolism Collagen Type III / metabolism
liver morphological changes senescence

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
12 Sep 2024
Historique:
received: 14 08 2024
revised: 03 09 2024
accepted: 04 09 2024
medline: 28 9 2024
pubmed: 28 9 2024
entrez: 28 9 2024
Statut: epublish

Résumé

Age-related liver changes can have important implications for health and metabolic function. This study aimed to describe the morphoquantitative alterations of the liver in senescent rats compared to adult rats. Twelve male rats were used, divided into 6-month-old adults (group A) and 36-month-old senescent rats (group S). Morphometric and histopathological studies, quantification of collagen types I and III, and stereological analyses were performed to determine the volume density of mononucleated (Vv

Identifiants

DOI: 10.3390/ijms25189846 PMID: 39337332
pubmed: 39337332
pii: ijms25189846
doi: 10.3390/ijms25189846
pii:
doi:

Substances chimiques

Collagen Type I 0
Collagen Type III 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Doctorate Program in Morphological Sciences, Universidad de La Frontera, Chile
ID : No number

Auteurs

Ruth Maldonado-Rengel (R)

Doctoral Program in Morphological Sciences, Faculty of Medicine, Universidad de La Frontera, Avenida Francisco Salazar 01145, Temuco 4811230, Chile.
Department of Health Sciences, Universidad Técnica Particular de Loja, San Cayetano Alto, Calle París, Loja 110107, Ecuador.
ORCID: 0000-0002-6435-1729

Zaida Sócola-Barsallo (Z)

Department of Health Sciences, Universidad Técnica Particular de Loja, San Cayetano Alto, Calle París, Loja 110107, Ecuador.
ORCID: 0000-0002-4207-8928

Bélgica Vásquez (B)

Department of Basic Sciences, Faculty of Medicine, Universidad de La Frontera, Avenida Francisco Salazar 01145, Temuco 4811230, Chile.
Centre of Excellence in Morphological and Surgical Studies, Universidad de La Frontera, Avenida Francisco Salazar 01145, Temuco 4811230, Chile.
ORCID: 0000-0002-4106-3548

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Alterations of Liver Morphology in Senescent Rats.
questionsmedicales.fr › Système digestif › Foie › Alterations of Liver Morphology in Senescent Rats.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Alterations of Liver Morphology in Senescent Rats.
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Vieillissement › Alterations of Liver Morphology in Senescent Rats.
questionsmedicales.fr › Cellules › Cellules épithéliales › Hépatocytes › Alterations of Liver Morphology in Senescent Rats.
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Noyau de la cellule › Alterations of Liver Morphology in Senescent Rats.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Scléroprotéines › Protéines de la matrice extracellulaire › Collagène › Collagènes fibrillaires › Collagène de type I › Alterations of Liver Morphology in Senescent Rats.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Scléroprotéines › Protéines de la matrice extracellulaire › Collagène › Collagènes fibrillaires › Collagène de type III › Alterations of Liver Morphology in Senescent Rats.