Impact of Plasminogen Activator Inhibitor-1 Serum Levels and the -675 4G/5G Variant in the SERPINE1 Gene on Systemic Sclerosis in a Mexican Population.
PAI-1 and fibrotic diseases
PAI-1 in SSc
SERPINE1 4G/5G polymorphism
TGF-β and PAI-1 in SSc
soluble PAI-1 in autoimmune diseases
Journal
Life (Basel, Switzerland)
ISSN: 2075-1729
Titre abrégé: Life (Basel)
Pays: Switzerland
ID NLM: 101580444
Informations de publication
Date de publication:
23 Aug 2024
23 Aug 2024
Historique:
received:
30
07
2024
revised:
19
08
2024
accepted:
21
08
2024
medline:
28
9
2024
pubmed:
28
9
2024
entrez:
28
9
2024
Statut:
epublish
Résumé
Systemic sclerosis (SSc) is characterized by a complex interplay of vascular damage, inflammation, and fibrosis, affecting the skin and internal organs. Plasminogen activator inhibitor-1 (PAI-1), a protein encoded by the
Identifiants
pubmed: 39337840
pii: life14091056
doi: 10.3390/life14091056
pii:
doi:
Types de publication
Journal Article
Langues
eng