Quantifying brain development in the HEALthy Brain and Child Development (HBCD) Study: The magnetic resonance imaging and spectroscopy protocol.

Development HBCD Infant MRI MRS Protocol

Journal

Developmental cognitive neuroscience
ISSN: 1878-9307
Titre abrégé: Dev Cogn Neurosci
Pays: Netherlands
ID NLM: 101541838

Informations de publication

Date de publication:
21 Sep 2024
Historique:
received: 06 03 2024
revised: 29 08 2024
accepted: 13 09 2024
medline: 29 9 2024
pubmed: 29 9 2024
entrez: 28 9 2024
Statut: aheadofprint

Résumé

The HEALthy Brain and Child Development (HBCD) Study, a multi-site prospective longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and emotional development beginning prenatally and planned through early childhood. The acquisition of multimodal magnetic resonance-based brain development data is central to the study's core protocol. However, application of Magnetic Resonance Imaging (MRI) methods in this population is complicated by technical challenges and difficulties of imaging in early life. Overcoming these challenges requires an innovative and harmonized approach, combining age-appropriate acquisition protocols together with specialized pediatric neuroimaging strategies. The HBCD MRI Working Group aimed to establish a core acquisition protocol for all 27 HBCD Study recruitment sites to measure brain structure, function, microstructure, and metabolites. Acquisition parameters of individual modalities have been matched across MRI scanner platforms for harmonized acquisitions and state-of-the-art technologies are employed to enable faster and motion-robust imaging. Here, we provide an overview of the HBCD MRI protocol, including decisions of individual modalities and preliminary data. The result will be an unparalleled resource for examining early neurodevelopment which enables the larger scientific community to assess normative trajectories from birth through childhood and to examine the genetic, biological, and environmental factors that help shape the developing brain.

Identifiants

DOI: 10.1016/j.dcn.2024.101452 PMID: 39341120
pubmed: 39341120
pii: S1878-9293(24)00113-0
doi: 10.1016/j.dcn.2024.101452
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

101452

Informations de copyright

Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Tobias Kober and Tom Hilbert are employees of Siemens Healthineers International AG, Switzerland. Yulin Chang is an employee of Siemens Medical Solutions USA Inc. Dan Rettmann and Ralph Noeske are employed by GE HealthCare. Guillaume Gilbert, Yansong Zhao, Sandeep Ganji, and Maarten Versluis are employed by Philips Healthcare. Carina Lucena, Lucky Heisler-Roman, and Dhruman Goradia are employed by PrimeNeuro Inc. Under a license agreement between Philips and the Johns Hopkins University, Dr. van Zijl and the University are entitled to fees related to an imaging device used in the study discussed for publication. Dr. van Zijl also is a paid lecturer for Philips and receives research support from Philips. This arrangement has been reviewed and approved by the Johns Hopkins University in accordance with its conflict of interest policies. Damien Fair is a patent holder on the Framwise Integrated Real-Time Motion Monitoring (FIRMM) software. He is also a co-founder of Turing Medical Technologies, Inc. The nature of this financial interest and the design of the study have been reviewed by two committees at the University of Minnesota. They have put in place a plan to help ensure that this research is not affected by the financial interest. All other authors report no biomedical financial interests or potential conflicts of interest.

Auteurs

Douglas C Dean (DC)

Department of Pediatrics, University of Wisconsin-Madison, Madison, WI, USA; Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, USA; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA. Electronic address: deaniii@wisc.edu.

M Dylan Tisdall (MD)

Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Jessica L Wisnowski (JL)

Department of Pediatrics, Children's Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, CA, USA; Department of Radiology, Children's Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.

Eric Feczko (E)

Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA; Masonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA.

Borjan Gagoski (B)

Department of Radiology, Harvard Medical School, Boston, MA, USA; Fetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children's Hospital, Boston, MA, USA.

Andrew L Alexander (AL)

Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, USA; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA; Department of Psychiatry, University of Wisconsin-Madison, Madison, WI, USA.

Richard A E Edden (RAE)

Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.

Wei Gao (W)

Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Department of Biomedical Sciences and Imaging, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Timothy J Hendrickson (TJ)

Masonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA; Minnesota Supercomputing Institute, University of Minnesota, Minneapolis, MN, USA; Bioinformatics and Computational Biology Program, University of Minnesota, Minneapolis, MN, USA.

Brittany R Howell (BR)

Fralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA, USA; Department of Human Development and Family Science, Virginia Tech, Blacksburg, VA, USA.

Hao Huang (H)

Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

Kathryn L Humphreys (KL)

Department of Psychology and Human Development, Vanderbilt University, Nashville, TN, USA.

Tracy Riggins (T)

Department of Psychology, University of Maryland, College Park, MD, USA.

Chad M Sylvester (CM)

Department of Psychiatry, Washington University in St. Louis, St. Louis, MO, USA; Department of Radiology, Washington University in St. Louis, St. Louis, MO, USA; Taylor Family Institute for Innovative Psychiatric Research, Washington University in St. Louis, St. Louis, MO, USA.

Kimberly B Weldon (KB)

Masonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA.

Essa Yacoub (E)

Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, USA.

Banu Ahtam (B)

Fetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children's Hospital, Boston, MA, USA; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.

Natacha Beck (N)

McGill Centre for Integrative Neuroscience, McGill University, Montréal, Québec, Canada; Montréal Neurological Institute-Hospital, Montréal, Québec, Canada; McConnell Brain Imaging Centre, McGill University, Montréal, Québec, Canada.

Suchandrima Banerjee (S)

GE HealthCare, Menlo Park, CA, USA.

Sergiy Boroday (S)

McGill Centre for Integrative Neuroscience, McGill University, Montréal, Québec, Canada; Montréal Neurological Institute-Hospital, Montréal, Québec, Canada; McConnell Brain Imaging Centre, McGill University, Montréal, Québec, Canada.

Arvind Caprihan (A)

The Mind Research Network, Albuquerque, NM, USA.

Bryan Caron (B)

McGill Centre for Integrative Neuroscience, McGill University, Montréal, Québec, Canada; Montréal Neurological Institute-Hospital, Montréal, Québec, Canada; McConnell Brain Imaging Centre, McGill University, Montréal, Québec, Canada.

Samuel Carpenter (S)

Department of Psychiatry, Oregon Health & Science University, Portland, OR, USA.

Yulin Chang (Y)

Siemens Medical Solutions USA Inc, PA, USA.

Ai Wern Chung (AW)

Fetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children's Hospital, Boston, MA, USA; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.

Matthew Cieslak (M)

Penn Lifespan Informatics and Neuroimaging Center (PennLINC), Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

William T Clarke (WT)

Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

Anders Dale (A)

Department of Radiology, University of California San Diego, La Jolla, CA, USA; Multimodal Imaging Laboratory, University of California San Diego, La Jolla, CA, USA; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA; Department of Neurosciences, University of California San Diego, La Jolla, CA, USA.

Samir Das (S)

McGill Centre for Integrative Neuroscience, McGill University, Montréal, Québec, Canada; Montréal Neurological Institute-Hospital, Montréal, Québec, Canada; McConnell Brain Imaging Centre, McGill University, Montréal, Québec, Canada.

Christopher W Davies-Jenkins (CW)

Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.

Alexander J Dufford (AJ)

Department of Psychiatry and Center for Mental Health Innovation, Oregon Health & Science University, Portland, OR, USA.

Alan C Evans (AC)

McGill Centre for Integrative Neuroscience, McGill University, Montréal, Québec, Canada; Montréal Neurological Institute-Hospital, Montréal, Québec, Canada; McConnell Brain Imaging Centre, McGill University, Montréal, Québec, Canada.

Laetitia Fesselier (L)

McGill Centre for Integrative Neuroscience, McGill University, Montréal, Québec, Canada; Montréal Neurological Institute-Hospital, Montréal, Québec, Canada; McConnell Brain Imaging Centre, McGill University, Montréal, Québec, Canada.

Sandeep K Ganji (SK)

MR Clinical Science, Philips Healthcare, Best, the Netherlands.

Guillaume Gilbert (G)

MR Clinical Science, Philips Healthcare, Mississauga, Ontario, Canada.

Alice M Graham (AM)

Department of Psychiatry, Oregon Health & Science University, Portland, OR, USA.

Aaron T Gudmundson (AT)

Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.

Maren Macgregor-Hannah (M)

Masonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA; Minnesota Supercomputing Institute, University of Minnesota, Minneapolis, MN, USA.

Michael P Harms (MP)

Department of Psychiatry, Washington University in St. Louis, St. Louis, MO, USA.

Tom Hilbert (T)

Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Lausanne, Switzerland,; Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland,; LTS5, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Steve C N Hui (SCN)

Developing Brain Institute, Children's National Hospital, Washington, DC, USA; Department of Radiology, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA; Department of Pediatrics, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.

M Okan Irfanoglu (MO)

Quantitative Medical Imaging Laboratory, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USA.

Steven Kecskemeti (S)

Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.

Tobias Kober (T)

Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Lausanne, Switzerland,; Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland,; LTS5, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Joshua M Kuperman (JM)

Department of Radiology, University of California San Diego, La Jolla, CA, USA.

Bidhan Lamichhane (B)

Center for Health Sciences, Oklahoma State University, Tulsa, OK, USA.

Bennett A Landman (BA)

Department of Electrical and Computer Engineering, Vanderbilt University, Nashville, TN, USA.

Xavier Lecour-Bourcher (X)

McGill Centre for Integrative Neuroscience, McGill University, Montréal, Québec, Canada; Montréal Neurological Institute-Hospital, Montréal, Québec, Canada; McConnell Brain Imaging Centre, McGill University, Montréal, Québec, Canada.

Erik G Lee (EG)

Masonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA; Minnesota Supercomputing Institute, University of Minnesota, Minneapolis, MN, USA; Bioinformatics and Computational Biology Program, University of Minnesota, Minneapolis, MN, USA.

Xu Li (X)

Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.

Leigh MacIntyre (L)

McGill Centre for Integrative Neuroscience, McGill University, Montréal, Québec, Canada; Montréal Neurological Institute-Hospital, Montréal, Québec, Canada; Lasso Informatics, Canada.

Cecile Madjar (C)

McGill Centre for Integrative Neuroscience, McGill University, Montréal, Québec, Canada; Montréal Neurological Institute-Hospital, Montréal, Québec, Canada; McConnell Brain Imaging Centre, McGill University, Montréal, Québec, Canada.

Mary Kate Manhard (MK)

Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Andrew R Mayer (AR)

The Mind Research Network, Albuquerque, NM, USA.

Kahini Mehta (K)

Penn Lifespan Informatics and Neuroimaging Center (PennLINC), Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Lucille A Moore (LA)

Masonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA.

Saipavitra Murali-Manohar (S)

Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.

Cristian Navarro (C)

Center for Neurodevelopmental and Imaging Research, Kennedy Krieger Institute, Baltimore, MD, USA.

Mary Beth Nebel (MB)

Center for Neurodevelopmental and Imaging Research, Kennedy Krieger Institute, Baltimore, MD, USA; Department of Neurology, The Johns Hopkins School of Medicine, Baltimore, MD, USA.

Sharlene D Newman (SD)

Alabama Life Research Institute, University of Alabama, Tuscaloosa, AL, USA; Department of Psychology, University of Alabama, Tuscaloosa, AL, USA.

Allen T Newton (AT)

Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, USA; Monroe Carell Jr. Children's Hospital at Vandebrilt, Vanderbilt University Medical Center, Nashville, TN, USA.

Ralph Noeske (R)

GE HealthCare, Munich, Germany.

Elizabeth S Norton (ES)

Department of Communication Sciences and Disorders, School of Communication, Northwestern University, Evanston, IL, USA; Department of Medical Social Sciences, Feinberg School of Medicine, Chicago, IL, USA.

Georg Oeltzschner (G)

Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.

Regis Ongaro-Carcy (R)

McGill Centre for Integrative Neuroscience, McGill University, Montréal, Québec, Canada; Montréal Neurological Institute-Hospital, Montréal, Québec, Canada; McConnell Brain Imaging Centre, McGill University, Montréal, Québec, Canada.

Xiawei Ou (X)

Department of Radiology, University of Arkansas for Medical Sciences, Little Rock, AR, USA; Arkansas Children's Research Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

Minhui Ouyang (M)

Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

Todd B Parrish (TB)

Department of Radiology, Feinberg School of Medicine, Chicago, IL, USA; Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA.

James J Pekar (JJ)

Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.

Thomas Pengo (T)

Masonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA; Minnesota Supercomputing Institute, University of Minnesota, Minneapolis, MN, USA.

Carlo Pierpaoli (C)

Quantitative Medical Imaging Laboratory, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USA.

Russell A Poldrack (RA)

Department of Psychology, Stanford University, Stanford, CA, USA.

Vidya Rajagopalan (V)

Department of Pediatrics, Children's Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, CA, USA; Department of Radiology, Children's Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.

Dan W Rettmann (DW)

GE HealthCare, Rochester, MN, USA.

Pierre Rioux (P)

McGill Centre for Integrative Neuroscience, McGill University, Montréal, Québec, Canada; Montréal Neurological Institute-Hospital, Montréal, Québec, Canada; McConnell Brain Imaging Centre, McGill University, Montréal, Québec, Canada.

Jens T Rosenberg (JT)

Advanced Magnetic Resonance Imaging and Spectroscopy Facility, McKnight Brain Institute, University of Florida, Gainesville, FL, USA.

Taylor Salo (T)

Penn Lifespan Informatics and Neuroimaging Center (PennLINC), Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Theodore D Satterthwaite (TD)

Penn Lifespan Informatics and Neuroimaging Center (PennLINC), Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Lisa S Scott (LS)

Department of Psychology, University of Florida, Gainesville, FL, USA.

Eunkyung Shin (E)

Department of Psychology, Pennsylvania State University, University Park, PA, USA.

Gizeaddis Simegn (G)

Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.

W Kyle Simmons (WK)

Department of Pharmacology and Physiology, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA; OSU Biomedical Imaging Center, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.

Yulu Song (Y)

Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.

Barry J Tikalsky (BJ)

Masonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA.

Jean Tkach (J)

Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Peter C M van Zijl (PCM)

Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.

Jennifer Vannest (J)

Department of Communication Sciences and Disorders, University of Cincinnati, Cincinnati, OH, USA; Communication Sciences Research Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Maarten Versluis (M)

MR Clinical Science, Philips Healthcare, Best, the Netherlands.

Yansong Zhao (Y)

MR Clinical Science, Philips Healthcare, Cleveland, OH, USA.

Helge J Zöllner (HJ)

Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA.

Damien A Fair (DA)

Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA; Masonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA; Institute of Child Development, University of Minnesota, Minneapolis, MN, USA. Electronic address: faird@umn.edu.

Christopher D Smyser (CD)

Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA; Department of Pediatrics, Washington University in St. Louis, St. Louis, MO, USA; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA. Electronic address: smyserc@wustl.edu.

Jed T Elison (JT)

Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA; Masonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA; Institute of Child Development, University of Minnesota, Minneapolis, MN, USA. Electronic address: jtelison@umn.edu.

Classifications MeSH