Total-Body PET/CT: Challenges and Opportunities.

Long-axial field-of-view (LAFOV) systems have changed the field of molecular imaging. Since their introduction, many PET centers have installed these next-generation digital systems to provide more detailed imaging and acquire PET images in a single bed position. Indeed, vertex to thigh imaging for oncological indications can be obtained in most of the population with the currently available LAFOV systems. Moreover, Total Body (TB) PET, a subtype of LAFOV, enables imaging the entire patient-from vertex through the toes-with one bed-position for most of the population. This review aims to identify possible challenges and opportunities for PET-centers working with TB and LAFOV systems. Emphasis is placed on the strength and weaknesses in clinical routine of currently available and upcoming TB and LAFOV PET systems.

Informations de copyright

Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest AR has received research support and speaker honoraria from Siemens. LN is principal investigator of several service agreements with United Imaging Healthcare. LN receives though UC Davis a recurrent gift from United Imaging Healthcare that support research (postdoctoral salary). LN is site PI of clinical trials supported by Novartis Pharmaceuticals Corporation. LN is PI of clinical trials supported by Telix Pharmaceuticals and Lantheus Medical Imaging and Curium Pharma Healthcare. LN is a co-investigator of a clinical trial supported by Lilly. UC Davis has a revenue sharing agreement with United Imaging Healthcare. Lorenzo Nardo has a speaking engagement agreement with Lilly. AP received consulting fees from GE. IA is PI of clinical trials supported by Alpha9 Oncology and has received speaker honoraria from Novartis outside of the present work. All other authors have no conflicts of interest to report.