Evaluation of the Biocompatibility of Periodontal Dressings: An

Biocompatibility MTT assay gingival fibroblast cells in vitro study periodontal dressings

Journal

Journal of pharmacy & bioallied sciences
ISSN: 0976-4879
Titre abrégé: J Pharm Bioallied Sci
Pays: India
ID NLM: 101537209

Informations de publication

Date de publication:
Jul 2024
Historique:
received: 01 04 2024
revised: 05 04 2024
accepted: 09 04 2024
medline: 30 9 2024
pubmed: 30 9 2024
entrez: 30 9 2024
Statut: ppublish

Résumé

Periodontal dressings play a crucial role in post-operative management of periodontal surgeries by protecting surgical sites and promoting wound healing. Biocompatibility evaluation is essential to ensure the safety and effectiveness of these materials. This study aims to assess the biocompatibility of periodontal dressings through an In this The MTT assay revealed that Dressing A exhibited the highest cell viability with an absorbance value of 0.8 ± 0.1, followed by Dressing B with a value of 0.6 ± 0.2 and Dressing C with a value of 0.5 ± 0.1. Microscopic analysis showed normal cell morphology and attachment in cells exposed to Dressing A and Dressing B extracts, while cells exposed to Dressing C exhibited slight detachment and irregular morphology. Our findings suggest that Dressing A and Dressing B demonstrate favorable biocompatibility profiles, as evidenced by higher cell viability and normal cell morphology.

Sections du résumé

Background UNASSIGNED
Periodontal dressings play a crucial role in post-operative management of periodontal surgeries by protecting surgical sites and promoting wound healing. Biocompatibility evaluation is essential to ensure the safety and effectiveness of these materials. This study aims to assess the biocompatibility of periodontal dressings through an
Materials and Methods UNASSIGNED
In this
Results UNASSIGNED
The MTT assay revealed that Dressing A exhibited the highest cell viability with an absorbance value of 0.8 ± 0.1, followed by Dressing B with a value of 0.6 ± 0.2 and Dressing C with a value of 0.5 ± 0.1. Microscopic analysis showed normal cell morphology and attachment in cells exposed to Dressing A and Dressing B extracts, while cells exposed to Dressing C exhibited slight detachment and irregular morphology.
Conclusion UNASSIGNED
Our findings suggest that Dressing A and Dressing B demonstrate favorable biocompatibility profiles, as evidenced by higher cell viability and normal cell morphology.

Identifiants

pubmed: 39346369
doi: 10.4103/jpbs.jpbs_335_24
pii: JPBS-16-2500
pmc: PMC11426820
doi:

Types de publication

Journal Article

Langues

eng

Pagination

S2500-S2502

Informations de copyright

Copyright: © 2024 Journal of Pharmacy and Bioallied Sciences.

Déclaration de conflit d'intérêts

There are no conflicts of interest.

Auteurs

Fatema Akhter (F)

Department of Surgical and Diagnostic Sciences, College of Dentistry, Dar Al Uloom University, Riyadh, Saudi Arabia.

Classifications MeSH