Evaluation of the Biocompatibility of Periodontal Dressings: An
Biocompatibility
MTT assay
gingival fibroblast cells
in vitro study
periodontal dressings
Journal
Journal of pharmacy & bioallied sciences
ISSN: 0976-4879
Titre abrégé: J Pharm Bioallied Sci
Pays: India
ID NLM: 101537209
Informations de publication
Date de publication:
Jul 2024
Jul 2024
Historique:
received:
01
04
2024
revised:
05
04
2024
accepted:
09
04
2024
medline:
30
9
2024
pubmed:
30
9
2024
entrez:
30
9
2024
Statut:
ppublish
Résumé
Periodontal dressings play a crucial role in post-operative management of periodontal surgeries by protecting surgical sites and promoting wound healing. Biocompatibility evaluation is essential to ensure the safety and effectiveness of these materials. This study aims to assess the biocompatibility of periodontal dressings through an In this The MTT assay revealed that Dressing A exhibited the highest cell viability with an absorbance value of 0.8 ± 0.1, followed by Dressing B with a value of 0.6 ± 0.2 and Dressing C with a value of 0.5 ± 0.1. Microscopic analysis showed normal cell morphology and attachment in cells exposed to Dressing A and Dressing B extracts, while cells exposed to Dressing C exhibited slight detachment and irregular morphology. Our findings suggest that Dressing A and Dressing B demonstrate favorable biocompatibility profiles, as evidenced by higher cell viability and normal cell morphology.
Sections du résumé
Background
UNASSIGNED
Periodontal dressings play a crucial role in post-operative management of periodontal surgeries by protecting surgical sites and promoting wound healing. Biocompatibility evaluation is essential to ensure the safety and effectiveness of these materials. This study aims to assess the biocompatibility of periodontal dressings through an
Materials and Methods
UNASSIGNED
In this
Results
UNASSIGNED
The MTT assay revealed that Dressing A exhibited the highest cell viability with an absorbance value of 0.8 ± 0.1, followed by Dressing B with a value of 0.6 ± 0.2 and Dressing C with a value of 0.5 ± 0.1. Microscopic analysis showed normal cell morphology and attachment in cells exposed to Dressing A and Dressing B extracts, while cells exposed to Dressing C exhibited slight detachment and irregular morphology.
Conclusion
UNASSIGNED
Our findings suggest that Dressing A and Dressing B demonstrate favorable biocompatibility profiles, as evidenced by higher cell viability and normal cell morphology.
Identifiants
pubmed: 39346369
doi: 10.4103/jpbs.jpbs_335_24
pii: JPBS-16-2500
pmc: PMC11426820
doi:
Types de publication
Journal Article
Langues
eng
Pagination
S2500-S2502Informations de copyright
Copyright: © 2024 Journal of Pharmacy and Bioallied Sciences.
Déclaration de conflit d'intérêts
There are no conflicts of interest.