Post-COVID-19 condition symptoms among emergency department patients tested for SARS-CoV-2 infection.
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
30 Sep 2024
30 Sep 2024
Historique:
received:
14
01
2024
accepted:
05
09
2024
medline:
1
10
2024
pubmed:
1
10
2024
entrez:
30
9
2024
Statut:
epublish
Résumé
Symptoms of the Post-COVID-19 Condition are often non-specific making it a challenge to distinguish them from symptoms due to other medical conditions. In this study, we compare the proportion of emergency department patients who developed symptoms consistent with the World Health Organization's Post-COVID-19 Condition clinical case definition between those who tested positive for Severe Acute Respiratory Syndrome Coronavirus-2 infection and time-matched patients who tested negative. Our results show that over one-third of emergency department patients with a proven acute infection meet Post-COVID-19 Condition criteria 3 months post-index visit. However, one in five test-negative patients who claim never having been infected also report symptoms consistent with Post-COVID-19 Condition highlighting the lack of specificity of the clinical case definition. Testing for SARS-CoV-2 during the acute phase of a suspected infection should continue until specific biomarkers of Post-COVID-19 Condition become available for diagnosis and treatment.
Identifiants
pubmed: 39349926
doi: 10.1038/s41467-024-52404-4
pii: 10.1038/s41467-024-52404-4
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
8449Subventions
Organisme : Gouvernement du Canada | Canadian Institutes of Health Research (Instituts de Recherche en Santé du Canada)
ID : 447679
Organisme : Gouvernement du Canada | Canadian Institutes of Health Research (Instituts de Recherche en Santé du Canada)
ID : 464947
Organisme : Gouvernement du Canada | Canadian Institutes of Health Research (Instituts de Recherche en Santé du Canada)
ID : 466880
Organisme : Saskatchewan Health Research Foundation (SHRF)
ID : 5357
Organisme : Genome British Columbia
ID : COV024
Organisme : Genome British Columbia
ID : VAC007
Investigateurs
Ian Martin
(I)
Sean Wormsbecker
(S)
Elizabeth Purssell
(E)
Lee Graham
(L)
Maja Stachura
(M)
Frank Scheuermeyer
(F)
John Taylor
(J)
Baljeet Brar
(B)
Daniel Ting
(D)
Rob Ohle
(R)
Ivy Cheng
(I)
Justin Yan
(J)
Gregory Clark
(G)
Joel Turner
(J)
Lars Grant
(L)
Sébastien Robert
(S)
Informations de copyright
© 2024. The Author(s).
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