Impact of dietary antioxidants on female infertility risk: evidence from NHANES.
Composite dietary antioxidant index
Cross-sectional study
Female infertility
NHANES
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
30 Sep 2024
30 Sep 2024
Historique:
received:
10
04
2024
accepted:
06
09
2024
medline:
1
10
2024
pubmed:
1
10
2024
entrez:
30
9
2024
Statut:
epublish
Résumé
The composite dietary antioxidant index (CDAI) serves as a valuable instrument for evaluating the intake of dietary antioxidants. This research aims to clarify the connection between CDAI and the risk of female infertility by analyzing data from the National Health and Nutrition Examination Survey from 2013 to 2018. Participants underwent two 24-h dietary recall interviews to calculate CDAI. Female infertility was determined through two questionnaires. Logistic regression model, restricted cubic spline and subgroup analysis were employed to examine the association between CDAI and female infertility. The study encompassed 2162 participants. Participants with female infertility had lower CDAI levels compared to those without. Following adjustment for confounding variables, a negative association between CDAI levels and female infertility was observed (Q4 vs. Q1, OR [95% CI] 0.392 [0.193, 0.795], P = 0.016). RCS demonstrated a statistically significant linear negative relationship between CDAI and female infertility. Subgroup analysis showed no significant interaction. This study illustrates a negative link between the CDAI and female infertility, indicating that higher consumption of dietary antioxidants may be associated with a reduced risk of female infertility. Additional rigorously designed prospective studies are necessary to validate these results.
Identifiants
pubmed: 39349955
doi: 10.1038/s41598-024-72434-8
pii: 10.1038/s41598-024-72434-8
doi:
Substances chimiques
Antioxidants
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
22623Subventions
Organisme : Science and Technology Bureau of Jiaxing City
ID : 2023AY31021
Organisme : Science and Technology Bureau of Jiaxing City
ID : 2022AY30022
Informations de copyright
© 2024. The Author(s).
Références
Carson, S. A. & Kallen, A. N. Diagnosis and management of infertility: A review. JAMA 326(1), 65–76 (2021).
pubmed: 34228062
pmcid: 9302705
doi: 10.1001/jama.2021.4788
Inhorn, M. C. & Patrizio, P. Infertility around the globe: New thinking on gender, reproductive technologies and global movements in the 21st century. Hum. Reprod. Update 21(4), 411–426 (2015).
pubmed: 25801630
doi: 10.1093/humupd/dmv016
Duckitt, K. Infertility and subfertility. Clin. Evid. 9, 2044–2073 (2003).
Agarwal, A., Aponte-Mellado, A., Premkumar, B. J., Shaman, A. & Gupta, S. The effects of oxidative stress on female reproduction: A review. Reprod. Biol. Endocrinol. 10, 49 (2012).
pubmed: 22748101
pmcid: 3527168
doi: 10.1186/1477-7827-10-49
Al-Gubory, K. H., Fowler, P. A. & Garrel, C. The roles of cellular reactive oxygen species, oxidative stress and antioxidants in pregnancy outcomes. Int. J. Biochem. Cell Biol. 42(10), 1634–1650 (2010).
pubmed: 20601089
doi: 10.1016/j.biocel.2010.06.001
Showell, M. G., Mackenzie-Proctor, R., Jordan, V. & Hart, R. J. Antioxidants for female subfertility. Cochrane Database Syst. Rev. 8(8), CD007807 (2020).
pubmed: 32851663
Kabodmehri, R. et al. Female infertility and dietary antioxidant index (DAI); A case-control study. BMC Womens Health 23(1), 608 (2023).
pubmed: 37974175
pmcid: 10655436
doi: 10.1186/s12905-023-02747-9
Ruder, E. H., Hartman, T. J., Reindollar, R. H. & Goldman, M. B. Female dietary antioxidant intake and time to pregnancy among couples treated for unexplained infertility. Fertil. Steril. 101(3), 759–766 (2014).
pubmed: 24355050
doi: 10.1016/j.fertnstert.2013.11.008
Wright, M. E. et al. Development of a comprehensive dietary antioxidant index and application to lung cancer risk in a cohort of male smokers. Am. J. Epidemiol. 160(1), 68–76 (2004).
pubmed: 15229119
doi: 10.1093/aje/kwh173
Apel, K. & Hirt, H. Reactive oxygen species: Metabolism, oxidative stress, and signal transduction. Annu. Rev. Plant Biol. 55, 373–399 (2004).
pubmed: 15377225
doi: 10.1146/annurev.arplant.55.031903.141701
Yang, J., Qian, S., Na, X. & Zhao, A. Association between dietary and supplemental antioxidants intake and lung cancer risk: Evidence from a cancer screening trial. Antioxidants (Basel) 12(2), 338 (2023).
pubmed: 36829901
doi: 10.3390/antiox12020338
Sun, W. & Zhang, L. Antioxidant indexes and immune function of the intestinal flora of compound microecological preparations. Oxid. Med. Cell Longev. 2022, 5498514 (2022).
pubmed: 36238651
pmcid: 9553397
doi: 10.1155/2022/5498514
Tan, Z. et al. Association of dietary fiber, composite dietary antioxidant index and risk of death in tumor survivors: National health and nutrition examination survey 2001–2018. Nutrients 15(13), 2968 (2023).
pubmed: 37447293
pmcid: 10346686
doi: 10.3390/nu15132968
Zipf, G. et al. National health and nutrition examination survey: Plan and operations, 1999–2010. Vital Health Stat. 1(56), 1–37 (2013).
van der Pol, A., van Gilst, W. H., Voors, A. A. & van der Meer, P. Treating oxidative stress in heart failure: Past, present and future. Eur. J. Heart Fail. 21(4), 425–435 (2019).
pubmed: 30338885
doi: 10.1002/ejhf.1320
Bhardwaj, J. K., Panchal, H. & Saraf, P. Ameliorating effects of natural antioxidant compounds on female infertility: A review. Reprod. Sci. 28(5), 1227–1256 (2021).
pubmed: 32935256
doi: 10.1007/s43032-020-00312-5
Bisht, S., Faiq, M., Tolahunase, M. & Dada, R. Oxidative stress and male infertility. Nat. Rev. Urol. 14(8), 470–485 (2017).
pubmed: 28508879
doi: 10.1038/nrurol.2017.69
Lin, X. et al. Excessive oxidative stress in cumulus granulosa cells induced cell senescence contributes to endometriosis-associated infertility. Redox Biol. 30, 101431 (2020).
pubmed: 31972508
pmcid: 6974790
doi: 10.1016/j.redox.2020.101431
Agarwal, A., Gupta, S. & Sharma, R. K. Role of oxidative stress in female reproduction. Reprod. Biol. Endocrinol. 3, 28 (2005).
pubmed: 16018814
pmcid: 1215514
doi: 10.1186/1477-7827-3-28
Palomba, S. Is fertility reduced in ovulatory women with polycystic ovary syndrome? An opinion paper. Hum. Reprod. 36, 2421–2428 (2021).
pubmed: 34333641
doi: 10.1093/humrep/deab181
Palomba, S., Daolio, J. & La Sala, G. B. Oocyte competence in women with polycystic ovary syndrome. Trends Endocrinol. Metab. 28, 186–198 (2017).
pubmed: 27988256
doi: 10.1016/j.tem.2016.11.008
Palomba, S., Piltonen, T. T. & Giudice, L. C. Endometrial function in women with polycystic ovary syndrome: A comprehensive review. Hum. Reprod. Update 27, 584–618 (2021).
pubmed: 33302299
doi: 10.1093/humupd/dmaa051
Agarwal, A., Gupta, S. & Sharma, R. Oxidative stress and its implications in female infertility—A clinician’s perspective. Reprod. Biomed. Online 11(5), 641–650 (2005).
pubmed: 16409717
doi: 10.1016/S1472-6483(10)61174-1
Kaltsas, A. et al. The silent threat to women’s fertility: Uncovering the devastating effects of oxidative stress. Antioxidants (Basel) 12(8), 1490 (2023).
pubmed: 37627485
doi: 10.3390/antiox12081490
Di Tucci, C. et al. The role of alpha lipoic acid in female and male infertility: A systematic review. Gynecol. Endocrinol. 37(6), 497–505 (2021).
pubmed: 33345661
doi: 10.1080/09513590.2020.1843619
Agarwal, A. & Allamaneni, S. S. Role of free radicals in female reproductive diseases and assisted reproduction. Reprod. Biomed. Online 9(3), 338–347 (2004).
pubmed: 15353087
doi: 10.1016/S1472-6483(10)62151-7
De Cosmi, V. et al. Vitamin and carotenoid intake and outcomes of in vitro fertilization in women referring to an Italian fertility service: A cross-sectional analysis of a prospective cohort study. Antioxidants (Basel) 12(2), 286 (2023).
pubmed: 36829847
doi: 10.3390/antiox12020286
Batıoğlu, A. S., Sahin, U., Gürlek, B., Oztürk, N. & Unsal, E. The efficacy of melatonin administration on oocyte quality. Gynecol. Endocrinol. 28(2), 91–93 (2012).
pubmed: 21770829
doi: 10.3109/09513590.2011.589925
Metzler, M. A. & Sandell, L. L. Enzymatic metabolism of vitamin A in developing vertebrate embryos. Nutrients 8(12), 812 (2016).
pubmed: 27983671
pmcid: 5188467
doi: 10.3390/nu8120812
Akram, N. A., Shafiq, F. & Ashraf, M. Ascorbic acid-a potential oxidant scavenger and its role in plant development and abiotic stress tolerance. Front. Plant Sci. 8, 613 (2017).
pubmed: 28491070
pmcid: 5405147
doi: 10.3389/fpls.2017.00613
Vašková, J. et al. The importance of natural antioxidants in female reproduction. Antioxidants (Basel) 12(4), 907 (2023).
pubmed: 37107282
doi: 10.3390/antiox12040907
Sadeghi, F., Alavi-Naeini, A., Mardanian, F., Ghazvini, M. R. & Mahaki, B. Omega-3 and vitamin E co-supplementation can improve antioxidant markers in obese/overweight women with polycystic ovary syndrome. Int. J. Vitam Nutr. Res. 90(5–6), 477–483 (2020).
pubmed: 30961460
doi: 10.1024/0300-9831/a000588
Edwards, G., Olson, C. G., Euritt, C. P. & Koulen, P. Molecular mechanisms underlying the therapeutic role of vitamin E in age-related macular degeneration. Front. Neurosci. 16, 890021 (2022).
pubmed: 35600628
pmcid: 9114494
doi: 10.3389/fnins.2022.890021
Zhang, W. et al. Association between the oxidative balance score and telomere length from the national health and nutrition examination survey 1999–2002. Oxid. Med. Cell Longev. 2022, 1345071 (2022).
pubmed: 35186180
pmcid: 8850082
Alesi, S., Ee, C., Moran, L. J., Rao, V. & Mousa, A. Nutritional supplements and complementary therapies in polycystic ovary syndrome. Adv. Nutr. 13(4), 1243–1266 (2022).
pubmed: 34970669
doi: 10.1093/advances/nmab141
Mumford, S. L. et al. A prospective cohort study to evaluate the impact of diet, exercise, and lifestyle on fertility: Design and baseline characteristics. Am. J. Epidemiol. 189(11), 1254–1265 (2020).
pubmed: 32472141
pmcid: 7604525
doi: 10.1093/aje/kwaa073
Mojadadi, A., Au, A., Salah, W., Witting, P. & Ahmad, G. Role for selenium in metabolic homeostasis and human reproduction. Nutrients 13(9), 3256 (2021).
pubmed: 34579133
pmcid: 8469766
doi: 10.3390/nu13093256
Xie, Y., Kang, R., Klionsky, D. J. & Tang, D. GPX4 in cell death, autophagy, and disease. Autophagy 19(10), 2621–2638 (2023).
pubmed: 37272058
pmcid: 10472888
doi: 10.1080/15548627.2023.2218764
Dahlen, C. R., Reynolds, L. P. & Caton, J. S. Selenium supplementation and pregnancy outcomes. Front. Nutr. 9, 1011850 (2022).
pubmed: 36386927
pmcid: 9659920
doi: 10.3389/fnut.2022.1011850
Liu, C. A. et al. Muscle distribution in relation to all-cause and cause-specific mortality in young and middle-aged adults. J. Transl. Med. 21(1), 154 (2023).
pubmed: 36841788
pmcid: 9960213
doi: 10.1186/s12967-023-04008-7
Wang, H. & Chen, Y. Relationship between composite dietary antioxidant index and aging. Healthcare (Basel) 11, 2722 (2023).
pubmed: 37893796
doi: 10.3390/healthcare11202722
Wang, R., Feng, Y., Chen, J., Chen, Y. & Ma, F. Association between polyunsaturated fatty acid intake and infertility among American women aged 20–44 years. Front. Public Health 10, 938343 (2022).
pubmed: 36062133
pmcid: 9428268
doi: 10.3389/fpubh.2022.938343