Atypical tuberculous peritonitis presenting as a peritoneal pseudocyst in an immunocompetent adult: insights from a case and literature review.

Democratic Republic of the Congo Diagnosis challenge Extrapulmonary Tuberculosis Pseudocysts Tuberculous peritonitis Ventriculoperitoneal shunt

Journal

BMC infectious diseases
ISSN: 1471-2334
Titre abrégé: BMC Infect Dis
Pays: England
ID NLM: 100968551

Informations de publication

Date de publication:
30 Sep 2024
Historique:
received: 20 06 2024
accepted: 18 09 2024
medline: 1 10 2024
pubmed: 1 10 2024
entrez: 30 9 2024
Statut: epublish

Résumé

Tuberculous peritonitis often presents with nonspecific symptoms that can lead to diagnostic challenges, particularly when manifesting as peritoneal pseudocysts. This study highlights the clinical complexity and diagnostic approach of tuberculous peritonitis presented as a pseudocyst in an immunocompetent adult, an atypical scenario that is rarely documented. We report a detailed case of a 41-year-old man presenting with abdominal distension, pain, and significant weight loss over four months. Abdominal CT showed a peritoneal pseudocyst, initially misdiagnosed due to its resemblance to more common abdominal pathologies. The diagnosis of tuberculous peritonitis was confirmed through histopathological analysis. Additionally, a systematic literature review was conducted to identify and analyse similar cases, focusing on clinical presentations, diagnostic methods, and patient outcomes. Our patient exhibited classic symptoms of abdominal TB but was unique due to the absence of prior ventriculoperitoneal shunting, a common factor in similar cases. Our literature review found that such presentations typically result in diagnostic delays averaging five months, complicating patient management and outcomes. This review also underscores the importance of considering tuberculosis in the differential diagnosis of peritoneal pseudocysts, particularly in TB-endemic regions. This case and review emphasize the need for high clinical suspicion and prompt investigation of tuberculosis in patients presenting with atypical abdominal symptoms and pseudocysts. Improved diagnostic strategies, including early use of imaging and pathological evaluations, are essential for timely diagnosis and management, thereby improving patient outcomes in suspected cases of extrapulmonary tuberculosis.

Sections du résumé

BACKGROUND BACKGROUND
Tuberculous peritonitis often presents with nonspecific symptoms that can lead to diagnostic challenges, particularly when manifesting as peritoneal pseudocysts. This study highlights the clinical complexity and diagnostic approach of tuberculous peritonitis presented as a pseudocyst in an immunocompetent adult, an atypical scenario that is rarely documented.
CASE PRESENTATION METHODS
We report a detailed case of a 41-year-old man presenting with abdominal distension, pain, and significant weight loss over four months. Abdominal CT showed a peritoneal pseudocyst, initially misdiagnosed due to its resemblance to more common abdominal pathologies. The diagnosis of tuberculous peritonitis was confirmed through histopathological analysis. Additionally, a systematic literature review was conducted to identify and analyse similar cases, focusing on clinical presentations, diagnostic methods, and patient outcomes. Our patient exhibited classic symptoms of abdominal TB but was unique due to the absence of prior ventriculoperitoneal shunting, a common factor in similar cases. Our literature review found that such presentations typically result in diagnostic delays averaging five months, complicating patient management and outcomes. This review also underscores the importance of considering tuberculosis in the differential diagnosis of peritoneal pseudocysts, particularly in TB-endemic regions.
CONCLUSION CONCLUSIONS
This case and review emphasize the need for high clinical suspicion and prompt investigation of tuberculosis in patients presenting with atypical abdominal symptoms and pseudocysts. Improved diagnostic strategies, including early use of imaging and pathological evaluations, are essential for timely diagnosis and management, thereby improving patient outcomes in suspected cases of extrapulmonary tuberculosis.

Identifiants

pubmed: 39350023
doi: 10.1186/s12879-024-09955-0
pii: 10.1186/s12879-024-09955-0
doi:

Types de publication

Journal Article Case Reports Review Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1077

Informations de copyright

© 2024. The Author(s).

Références

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Auteurs

Jimmy Balibanga Minani (JB)

Department of Internal Medicine, Hôpital Provincial Général de Référence de Bukavu (HPGRB), Bukavu, South Kivu, Democratic Republic of the Congo. jimmyminj@gmail.com.
Faculty of Medicine, Université Catholique de Bukavu (UCB), Bukavu, South Kivu, Democratic Republic of the Congo. jimmyminj@gmail.com.

Wani Bisimwa (W)

Faculty of Medicine, Université Catholique de Bukavu (UCB), Bukavu, South Kivu, Democratic Republic of the Congo.
Department of Surgery, Hôpital Provincial Général de Référence de Bukavu (HPGRB), Bukavu, South Kivu, Democratic Republic of the Congo.

Fabrice Cikomola Gulimwentuga (F)

Faculty of Medicine, Université Catholique de Bukavu (UCB), Bukavu, South Kivu, Democratic Republic of the Congo.
Department of Surgery, Hôpital Provincial Général de Référence de Bukavu (HPGRB), Bukavu, South Kivu, Democratic Republic of the Congo.
Centre for Tropical Diseases and Global Health, Department of Medicine, Université Catholique de Bukavu (UCB), Bukavu, South Kivu, Democratic Republic of the Congo.

Aline Bedha (A)

Department of Internal Medicine, Hôpital Provincial Général de Référence de Bukavu (HPGRB), Bukavu, South Kivu, Democratic Republic of the Congo.
Faculty of Medicine, Université Catholique de Bukavu (UCB), Bukavu, South Kivu, Democratic Republic of the Congo.

Ghislain Maheshe Balemba (G)

Faculty of Medicine, Université Catholique de Bukavu (UCB), Bukavu, South Kivu, Democratic Republic of the Congo.
Department of Radiology, Hôpital Provincial Général de Référence de Bukavu (HPGRB), Bukavu, South Kivu, Democratic Republic of the Congo.

Guy-Quesney Mateso Mbale (GQ)

Faculty of Medicine, Université Catholique de Bukavu (UCB), Bukavu, South Kivu, Democratic Republic of the Congo.
Department of Intensive Care Medicine, Hôpital Provincial Général de Référence de Bukavu (HPGRB), Bukavu, South Kivu, Democratic Republic of the Congo.

David Lupande Mwenebitu (D)

Faculty of Medicine, Université Catholique de Bukavu (UCB), Bukavu, South Kivu, Democratic Republic of the Congo.
Centre for Tropical Diseases and Global Health, Department of Medicine, Université Catholique de Bukavu (UCB), Bukavu, South Kivu, Democratic Republic of the Congo.
Department of Laboratory, Hôpital Provincial Général de Référence de Bukavu (HPGRB), Bukavu, South Kivu, Democratic Republic of the Congo.

Pierrot Mulumeoderhwa Kahasha (P)

Faculty of Medicine, Université Catholique de Bukavu (UCB), Bukavu, South Kivu, Democratic Republic of the Congo.
Department of Pathology, Hôpital Provincial Général de Référence de Bukavu (HPGRB), Bukavu, South Kivu, Democratic Republic of the Congo.

Marius Baguma (M)

Department of Internal Medicine, Hôpital Provincial Général de Référence de Bukavu (HPGRB), Bukavu, South Kivu, Democratic Republic of the Congo.
Faculty of Medicine, Université Catholique de Bukavu (UCB), Bukavu, South Kivu, Democratic Republic of the Congo.
Centre for Tropical Diseases and Global Health, Department of Medicine, Université Catholique de Bukavu (UCB), Bukavu, South Kivu, Democratic Republic of the Congo.

Pacifique Mwene-Batu (P)

Faculty of Medicine, Université Catholique de Bukavu (UCB), Bukavu, South Kivu, Democratic Republic of the Congo.
École Régionale de Santé Publique (ERSP), Université Catholique de Bukavu (UCB), Bukavu, South Kivu, Democratic Republic of the Congo.

Patrick Dmc Katoto (PD)

Faculty of Medicine, Université Catholique de Bukavu (UCB), Bukavu, South Kivu, Democratic Republic of the Congo.
Centre for Tropical Diseases and Global Health, Department of Medicine, Université Catholique de Bukavu (UCB), Bukavu, South Kivu, Democratic Republic of the Congo.
Centre for Evidence Based Medicine, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

Tony Akilimali Shindano (TA)

Department of Internal Medicine, Hôpital Provincial Général de Référence de Bukavu (HPGRB), Bukavu, South Kivu, Democratic Republic of the Congo.
Faculty of Medicine, Université Catholique de Bukavu (UCB), Bukavu, South Kivu, Democratic Republic of the Congo.
Centre for Tropical Diseases and Global Health, Department of Medicine, Université Catholique de Bukavu (UCB), Bukavu, South Kivu, Democratic Republic of the Congo.

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