Epidemiological changes of scarlet fever before, during and after the COVID-19 pandemic in Chongqing, China: a 19-year surveillance and prediction study.


Journal

BMC public health
ISSN: 1471-2458
Titre abrégé: BMC Public Health
Pays: England
ID NLM: 100968562

Informations de publication

Date de publication:
30 Sep 2024
Historique:
received: 02 09 2023
accepted: 17 09 2024
medline: 1 10 2024
pubmed: 1 10 2024
entrez: 30 9 2024
Statut: epublish

Résumé

This study aimed to investigate the epidemiological changes in scarlet fever before, during and after the COVID-19 pandemic (2005-2023) and predict the incidence of the disease in 2024 and 2025 in Chongqing Municipality, Southwest China. Descriptive analysis was used to summarize the characteristics of the scarlet fever epidemic. Spatial autocorrelation analysis was utilized to explore the distribution pattern of the disease, and the seasonal autoregressive integrated moving average (SARIMA) model was constructed to predict its incidence in 2024 and 2025. Between 2005 and 2023, 9,593 scarlet fever cases were reported in Chongqing, which resulted in an annual average incidence of 1.6694 per 100,000 people. Children aged 3-7 were the primary victims of this disease, with the highest average incidence found among children aged 6 (5.0002 per 100,000 people). Kindergarten children were the dominant infected population, accounting for as much as 54.32% of cases, followed by students (34.09%). The incidence for the male was 1.51 times greater than that for the female. The monthly distribution of the incidence showed a bimodal pattern, with one peak occurring between April and June and another in November or December. The spatial autocorrelation analysis revealed that scarlet fever cases were markedly clustered; the areas with higher incidence were mainly concentrated in Chongqing's urban areas and its adjacent districts, and gradually spreading to remote areas after 2020. The incidence of scarlet fever increased by 106.54% and 39.33% in the post-upsurge period (2015-2019) and the dynamic zero-COVID period (2020-2022), respectively, compared to the pre-upsurge period (2005-2014) (P < 0.001). During the dynamic zero-COVID period, the incidence of scarlet fever decreased by 68.61%, 25.66%, and 10.59% (P < 0.001) in 2020, 2021, and 2022, respectively, compared to the predicted incidence. In 2023, after the dynamic zero-COVID period, the reported cases decreased to 1.5168 per 100,000 people unexpectedly instead of increasing. The cases of scarlet fever are predicted to increase in 2024 (675 cases) and 2025 (705 cases). Children aged 3-7 years are the most affected population, particularly males, and kindergartens and primary schools serving as transmission hotspots. It is predicted that the high incidence of scarlet fever in Chongqing will persist in 2024 and 2025, and the outer districts (counties) beyond urban zone would bear the brunt of the impact. Therefore, imminent public health planning and resource allocation should be focused within those areas.

Sections du résumé

BACKGROUND BACKGROUND
This study aimed to investigate the epidemiological changes in scarlet fever before, during and after the COVID-19 pandemic (2005-2023) and predict the incidence of the disease in 2024 and 2025 in Chongqing Municipality, Southwest China.
METHODS METHODS
Descriptive analysis was used to summarize the characteristics of the scarlet fever epidemic. Spatial autocorrelation analysis was utilized to explore the distribution pattern of the disease, and the seasonal autoregressive integrated moving average (SARIMA) model was constructed to predict its incidence in 2024 and 2025.
RESULTS RESULTS
Between 2005 and 2023, 9,593 scarlet fever cases were reported in Chongqing, which resulted in an annual average incidence of 1.6694 per 100,000 people. Children aged 3-7 were the primary victims of this disease, with the highest average incidence found among children aged 6 (5.0002 per 100,000 people). Kindergarten children were the dominant infected population, accounting for as much as 54.32% of cases, followed by students (34.09%). The incidence for the male was 1.51 times greater than that for the female. The monthly distribution of the incidence showed a bimodal pattern, with one peak occurring between April and June and another in November or December. The spatial autocorrelation analysis revealed that scarlet fever cases were markedly clustered; the areas with higher incidence were mainly concentrated in Chongqing's urban areas and its adjacent districts, and gradually spreading to remote areas after 2020. The incidence of scarlet fever increased by 106.54% and 39.33% in the post-upsurge period (2015-2019) and the dynamic zero-COVID period (2020-2022), respectively, compared to the pre-upsurge period (2005-2014) (P < 0.001). During the dynamic zero-COVID period, the incidence of scarlet fever decreased by 68.61%, 25.66%, and 10.59% (P < 0.001) in 2020, 2021, and 2022, respectively, compared to the predicted incidence. In 2023, after the dynamic zero-COVID period, the reported cases decreased to 1.5168 per 100,000 people unexpectedly instead of increasing. The cases of scarlet fever are predicted to increase in 2024 (675 cases) and 2025 (705 cases).
CONCLUSIONS CONCLUSIONS
Children aged 3-7 years are the most affected population, particularly males, and kindergartens and primary schools serving as transmission hotspots. It is predicted that the high incidence of scarlet fever in Chongqing will persist in 2024 and 2025, and the outer districts (counties) beyond urban zone would bear the brunt of the impact. Therefore, imminent public health planning and resource allocation should be focused within those areas.

Identifiants

pubmed: 39350134
doi: 10.1186/s12889-024-20116-5
pii: 10.1186/s12889-024-20116-5
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2674

Subventions

Organisme : Scientific Research Project of Chongqing Talent Plan
ID : cstc2022ycjh-bgzxm0251
Organisme : Scientific Research Project of Chongqing Talent Plan
ID : cstc2022ycjh-bgzxm0251
Organisme : Scientific Research Project of Chongqing Talent Plan
ID : cstc2022ycjh-bgzxm0251
Organisme : Scientific Research Project of Chongqing Talent Plan
ID : cstc2022ycjh-bgzxm0251
Organisme : Scientific Research Project of Chongqing Talent Plan
ID : cstc2022ycjh-bgzxm0251
Organisme : Scientific Research Project of Chongqing Talent Plan
ID : cstc2022ycjh-bgzxm0251
Organisme : Scientific Research Project of Chongqing Talent Plan
ID : cstc2022ycjh-bgzxm0251
Organisme : Scientific Research Project of Chongqing Talent Plan
ID : cstc2022ycjh-bgzxm0251
Organisme : the Key Research and Development Project in the Health Field of Chongqing
ID : CSTC2021jscx-gksb-N0003
Organisme : the Key Research and Development Project in the Health Field of Chongqing
ID : CSTC2021jscx-gksb-N0003
Organisme : the Key Research and Development Project in the Health Field of Chongqing
ID : CSTC2021jscx-gksb-N0003

Informations de copyright

© 2024. The Author(s).

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Auteurs

Rui Wu (R)

Chongqing Center for Disease Control and Prevention, No. 187 Tongxing North Road, Beibei district, Chongqing Municipality, China.

Yu Xiong (Y)

Chongqing Center for Disease Control and Prevention, No. 187 Tongxing North Road, Beibei district, Chongqing Municipality, China.

Ju Wang (J)

Chongqing Center for Disease Control and Prevention, No. 187 Tongxing North Road, Beibei district, Chongqing Municipality, China.

Baisong Li (B)

Chongqing Center for Disease Control and Prevention, No. 187 Tongxing North Road, Beibei district, Chongqing Municipality, China.

Lin Yang (L)

Chongqing Center for Disease Control and Prevention, No. 187 Tongxing North Road, Beibei district, Chongqing Municipality, China.

Han Zhao (H)

Chongqing Center for Disease Control and Prevention, No. 187 Tongxing North Road, Beibei district, Chongqing Municipality, China.

Jule Yang (J)

Chongqing Center for Disease Control and Prevention, No. 187 Tongxing North Road, Beibei district, Chongqing Municipality, China.

Tao Yin (T)

Chongqing Center for Disease Control and Prevention, No. 187 Tongxing North Road, Beibei district, Chongqing Municipality, China.

Jun Sun (J)

Chongqing Center for Disease Control and Prevention, No. 187 Tongxing North Road, Beibei district, Chongqing Municipality, China.

Li Qi (L)

Chongqing Center for Disease Control and Prevention, No. 187 Tongxing North Road, Beibei district, Chongqing Municipality, China.

Jiang Long (J)

Chongqing Center for Disease Control and Prevention, No. 187 Tongxing North Road, Beibei district, Chongqing Municipality, China.

Qin Li (Q)

Chongqing Center for Disease Control and Prevention, No. 187 Tongxing North Road, Beibei district, Chongqing Municipality, China.

Xiaoni Zhong (X)

School of Public Health and Management, Chongqing Medical University, No. 1 Yixueyuan Road, Yuzhong district, Chongqing Municipality, China.

Wenge Tang (W)

Chongqing Center for Disease Control and Prevention, No. 187 Tongxing North Road, Beibei district, Chongqing Municipality, China. wengetangcq@163.com.

Yaokai Chen (Y)

Chongqing Public Health Medical Center, No. 109 Baoyu Road, Shapingba district, Chongqing Municipality, China. yaokaichen@hotmail.com.

Kun Su (K)

Chongqing Center for Disease Control and Prevention, No. 187 Tongxing North Road, Beibei district, Chongqing Municipality, China. sukun325@163.com.
Chongqing Public Health Medical Center, No. 109 Baoyu Road, Shapingba district, Chongqing Municipality, China. sukun325@163.com.
School of Public Health and Management, Chongqing Medical University, No. 1 Yixueyuan Road, Yuzhong district, Chongqing Municipality, China. sukun325@163.com.

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