STABILITY OF MEDIALLY AND LATERALLY MALPOSITIONED SCREWS: A BIOMECHANICAL STUDY ON CADAVERS.

misplacement orthopedics pedicle screws pull-out strength spine instrumentation spine surgery

Journal

The spine journal : official journal of the North American Spine Society
ISSN: 1878-1632
Titre abrégé: Spine J
Pays: United States
ID NLM: 101130732

Informations de publication

Date de publication:
30 Sep 2024
Historique:
received: 31 01 2024
revised: 07 08 2024
accepted: 14 09 2024
medline: 3 10 2024
pubmed: 3 10 2024
entrez: 2 10 2024
Statut: aheadofprint

Résumé

Pedicle screw instrumentation is widely used in spine surgery. Axial screw misplacement is a common complication. In addition to the recognized neurovascular risks associated with screw misplacement, the biomechanical stability of misplaced screws remains a subject of debate. The present study investigates whether screw misplacement in the lumbar spine reduces mechanical screw hold. Cadaveric biomechanical study METHODS: Pedicle screw (mis)placement was planned for 12 fresh frozen cadaveric spines between the T12 and the L5 levels. The screws were then implanted into the vertebrae with the help of 3D-printed template guides. Pre- and post-instrumentation computed tomography (CT) scans were acquired for instrumentation planning and quantification of the misplacement. The instrumented vertebrae were potted into CT transparent boxes using Polymethyl methacrylate and mounted on a standardized biomechanical setup for pull-out (PO) testing with uniaxial tensile load. The bone density of all the specimens as per HU was comparable. The predicted pull-out force (POF) for screws medially misplaced by 2mm, 4mm, and 6mm was respectively 985 N (SD 474), 968 N (SD 476) and 822 N (SD 478). For screws laterally misplaced by 2mm, 4mm, and 6mm the POF was respectively 605 N (SD 473), 411 N (SD 475), and 334 N (SD 477). Screws that did not perforate the pedicle (control) resisted pull-out forces of 837 N (SD 471). Medial misplacement is associated with increased axial screw hold against static loads compared to correctly placed screws and laterally placed screws. In clinical settings, the reinsertion of medially misplaced screws should primarily aim to prevent neurological complications while the reinsertion of lateral misplaced screws should aim to prevent screw loosening.

Sections du résumé

BACKGROUND CONTEXT BACKGROUND
Pedicle screw instrumentation is widely used in spine surgery. Axial screw misplacement is a common complication. In addition to the recognized neurovascular risks associated with screw misplacement, the biomechanical stability of misplaced screws remains a subject of debate.
PURPOSE OBJECTIVE
The present study investigates whether screw misplacement in the lumbar spine reduces mechanical screw hold.
STUDY DESIGN/SETTING METHODS
Cadaveric biomechanical study METHODS: Pedicle screw (mis)placement was planned for 12 fresh frozen cadaveric spines between the T12 and the L5 levels. The screws were then implanted into the vertebrae with the help of 3D-printed template guides. Pre- and post-instrumentation computed tomography (CT) scans were acquired for instrumentation planning and quantification of the misplacement. The instrumented vertebrae were potted into CT transparent boxes using Polymethyl methacrylate and mounted on a standardized biomechanical setup for pull-out (PO) testing with uniaxial tensile load.
RESULTS RESULTS
The bone density of all the specimens as per HU was comparable. The predicted pull-out force (POF) for screws medially misplaced by 2mm, 4mm, and 6mm was respectively 985 N (SD 474), 968 N (SD 476) and 822 N (SD 478). For screws laterally misplaced by 2mm, 4mm, and 6mm the POF was respectively 605 N (SD 473), 411 N (SD 475), and 334 N (SD 477). Screws that did not perforate the pedicle (control) resisted pull-out forces of 837 N (SD 471).
CONCLUSIONS CONCLUSIONS
Medial misplacement is associated with increased axial screw hold against static loads compared to correctly placed screws and laterally placed screws.
CLINICAL SIGNIFICANCE CONCLUSIONS
In clinical settings, the reinsertion of medially misplaced screws should primarily aim to prevent neurological complications while the reinsertion of lateral misplaced screws should aim to prevent screw loosening.

Identifiants

pubmed: 39357743
pii: S1529-9430(24)01023-4
doi: 10.1016/j.spinee.2024.09.008
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024. Published by Elsevier Inc.

Déclaration de conflit d'intérêts

Declaration of competing interest One or more authors have financial commitments to disclose. The respective conflict of interest forms (COIs) have been duly submitted.

Auteurs

Christos Tsagkaris (C)

Department of Orthopedics, Balgrist University Hospital, Zurich, Switzerland; Spine Biomechanics, Department of Orthopedics, Balgrist University Hospital, Zurich, Switzerland.

Marie-Rosa Fasser (MR)

Spine Biomechanics, Department of Orthopedics, Balgrist University Hospital, Zurich, Switzerland; Institute for Biomechanics, ETH Zurich, Zurich, Switzerland.

Mazda Farshad (M)

Department of Orthopedics, Balgrist University Hospital, Zurich, Switzerland; Spine Biomechanics, Department of Orthopedics, Balgrist University Hospital, Zurich, Switzerland.

Caroline Passaplan (C)

Department of Orthopedics, Balgrist University Hospital, Zurich, Switzerland; Spine Biomechanics, Department of Orthopedics, Balgrist University Hospital, Zurich, Switzerland.

Frederic Cornaz (F)

Department of Orthopedics, Balgrist University Hospital, Zurich, Switzerland; Spine Biomechanics, Department of Orthopedics, Balgrist University Hospital, Zurich, Switzerland.

Jonas Widmer (J)

Department of Orthopedics, Balgrist University Hospital, Zurich, Switzerland; Spine Biomechanics, Department of Orthopedics, Balgrist University Hospital, Zurich, Switzerland. Electronic address: jonas.widmer@balgrist.ch.

José Miguel Spirig (JM)

Department of Orthopedics, Balgrist University Hospital, Zurich, Switzerland; Spine Biomechanics, Department of Orthopedics, Balgrist University Hospital, Zurich, Switzerland.

Classifications MeSH