Deep learning-derived optimal aviation strategies to control pandemics.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
02 Oct 2024
Historique:
received: 31 05 2024
accepted: 19 09 2024
medline: 3 10 2024
pubmed: 3 10 2024
entrez: 2 10 2024
Statut: epublish

Résumé

The COVID-19 pandemic affected countries across the globe, demanding drastic public health policies to mitigate the spread of infection, which led to economic crises as a collateral damage. In this work, we investigate the impact of human mobility, described via international commercial flights, on COVID-19 infection dynamics on a global scale. We developed a graph neural network (GNN)-based framework called Dynamic Weighted GraphSAGE (DWSAGE), which operates over spatiotemporal graphs and is well-suited for dynamically changing flight information updated daily. This architecture is designed to be structurally sensitive, capable of learning the relationships between edge features and node features. To gain insights into the influence of air traffic on infection spread, we conducted local sensitivity analysis on our model through perturbation experiments. Our analyses identified Western Europe, the Middle East, and North America as leading regions in fueling the pandemic due to the high volume of air traffic originating or transiting through these areas. We used these observations to propose air traffic reduction strategies that can significantly impact controlling the pandemic with minimal disruption to human mobility. Our work provides a robust deep learning-based tool to study global pandemics and is of key relevance to policymakers for making informed decisions regarding air traffic restrictions during future outbreaks.

Identifiants

pubmed: 39358428
doi: 10.1038/s41598-024-73639-7
pii: 10.1038/s41598-024-73639-7
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

22926

Informations de copyright

© 2024. The Author(s).

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Auteurs

Syed Rizvi (S)

Department of Computer Science, Yale University, New Haven, CT, 06511, USA.

Akash Awasthi (A)

Department of Electrical and Computer Engineering, University of Houston, Houston, TX, 77004, USA.

Maria J Peláez (MJ)

Mathematics in Medicine Program, Department of Medicine, Houston Methodist Research Institute, Houston, TX, 77030, USA.

Zhihui Wang (Z)

Mathematics in Medicine Program, Department of Medicine, Houston Methodist Research Institute, Houston, TX, 77030, USA.
Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY, 10065, USA.
Neal Cancer Center, Houston Methodist Research Institute, Houston, TX, 77030, USA.

Vittorio Cristini (V)

Mathematics in Medicine Program, Department of Medicine, Houston Methodist Research Institute, Houston, TX, 77030, USA.
Neal Cancer Center, Houston Methodist Research Institute, Houston, TX, 77030, USA.
Department of Imaging Physics, The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77230, USA.
Physiology, Biophysics, and Systems Biology Program, Graduate School of Medical Sciences, Weill Cornell Medicine, New York, NY, 10065, USA.

Hien Van Nguyen (H)

Department of Electrical and Computer Engineering, University of Houston, Houston, TX, 77004, USA.

Prashant Dogra (P)

Mathematics in Medicine Program, Department of Medicine, Houston Methodist Research Institute, Houston, TX, 77030, USA. pdogra@houstonmethodist.org.
Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY, 10065, USA. pdogra@houstonmethodist.org.

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