European Society of Intensive Care Medicine guidelines on end of life and palliative care in the intensive care unit.

Communication Conflict management Cultural variations Decision-making End of life Family-centered care GRADE Intensive care unit Palliative care

Journal

Intensive care medicine
ISSN: 1432-1238
Titre abrégé: Intensive Care Med
Pays: United States
ID NLM: 7704851

Informations de publication

Date de publication:
03 Oct 2024
Historique:
received: 04 07 2024
accepted: 28 07 2024
medline: 3 10 2024
pubmed: 3 10 2024
entrez: 3 10 2024
Statut: aheadofprint

Résumé

The European Society of Intensive Care Medicine (ESICM) has developed evidence-based recommendations and expert opinions about end-of-life (EoL) and palliative care for critically ill adults to optimize patient-centered care, improving outcomes of relatives, and supporting intensive care unit (ICU) staff in delivering compassionate and effective EoL and palliative care. An international multi-disciplinary panel of clinical experts, a methodologist, and representatives of patients and families examined key domains, including variability across countries, decision-making, palliative-care integration, communication, family-centered care, and conflict management. Eight evidence-based recommendations (6 of low level of evidence and 2 of high level of evidence) and 19 expert opinions were presented. EoL legislation and the importance of respecting the autonomy and preferences of patients were given close attention. Differences in EoL care depending on country income and healthcare provision were considered. Structured EoL decision-making strategies are recommended to improve outcomes of patients and relatives, as well as staff satisfaction and mental health. Early integration of palliative care and the use of standardized tools for symptom assessment are suggested for patients at high risk of dying. Communication training for ICU staff and printed communication aids for families are advocated to improve outcomes and satisfaction. Methods for enhancing family-centeredness of care include structured family conferences and culturally sensitive interventions. Conflict-management protocols and strategies to prevent burnout among healthcare professionals are also considered. The work done to develop these guidelines highlights many areas requiring further research.

Identifiants

pubmed: 39361081
doi: 10.1007/s00134-024-07579-1
pii: 10.1007/s00134-024-07579-1
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s).

Références

Sprung CL, Ricou B, Hartog CS et al (2019) Changes in end-of-life practices in European intensive care units from 1999 to 2016. JAMA 322:1–12. https://doi.org/10.1001/jama.2019.14608
doi: 10.1001/jama.2019.14608
Kelley AS, Morrison RS (2015) Palliative care for the seriously ill. N Engl J Med 373:747–755. https://doi.org/10.1056/NEJMra1404684
doi: 10.1056/NEJMra1404684 pubmed: 26287850 pmcid: 4671283
Rodriguez KL, Barnato AE, Arnold RM (2007) Perceptions and utilization of palliative care services in acute care hospitals. J Palliat Med 10:99–110. https://doi.org/10.1089/jpm.2006.0155
doi: 10.1089/jpm.2006.0155 pubmed: 17298258
Azoulay E, Metnitz B, Sprung C et al (2009) End-of-life practices in 282 intensive care units: data from the SAPS 3 database. Intensive Care Med 35:623–630. https://doi.org/10.1007/s00134-008-1310-6
doi: 10.1007/s00134-008-1310-6 pubmed: 18850088
Sprung CL, Cohen SL, Sjokvist P et al (2003) End-of-life practices in European intensive care units: the Ethicus Study. JAMA 290:790–797. https://doi.org/10.1001/jama.290.6.790
doi: 10.1001/jama.290.6.790 pubmed: 12915432
Curtis JR, Tonelli MR (2011) Shared decision-making in the ICU: value, challenges, and limitations. Am J Respir Crit Care Med 183:840–841. https://doi.org/10.1164/rccm.201011-1836ED
doi: 10.1164/rccm.201011-1836ED pubmed: 21474424
Quill TE, Brody H (1996) Physician recommendations and patient autonomy: finding a balance between physician power and patient choice. Ann Intern Med 125:763–769. https://doi.org/10.7326/0003-4819-125-9-199611010-00010
doi: 10.7326/0003-4819-125-9-199611010-00010 pubmed: 8929011
Abernethy AP, Currow DC, Fazekas BS et al (2008) Specialized palliative care services are associated with improved short- and long-term caregiver outcomes. Support Care Cancer Off J Multinatl Assoc Support Care Cancer 16:585–597. https://doi.org/10.1007/s00520-007-0342-8
doi: 10.1007/s00520-007-0342-8
Nelson JE, Hanson LC, Keller KL et al (2017) The voice of surrogate decision-makers. family responses to prognostic information in chronic critical illness. Am J Respir Crit Care Med 196:864–872. https://doi.org/10.1164/rccm.201701-0201OC
doi: 10.1164/rccm.201701-0201OC pubmed: 28387538 pmcid: 5649978
Nelson JE, Puntillo KA, Pronovost PJ et al (2010) In their own words: patients and families define high-quality palliative care in the intensive care unit. Crit Care Med 38:808–818. https://doi.org/10.1097/ccm.0b013e3181c5887c
doi: 10.1097/ccm.0b013e3181c5887c pubmed: 20198726 pmcid: 3267550
Herridge MS, Azoulay É (2023) Outcomes after critical illness. N Engl J Med 388:913–924. https://doi.org/10.1056/NEJMra2104669
doi: 10.1056/NEJMra2104669 pubmed: 36884324
Azoulay E, Timsit J-F, Sprung CL et al (2009) Prevalence and factors of intensive care unit conflicts: the conflicus study. Am J Respir Crit Care Med 180:853–860. https://doi.org/10.1164/rccm.200810-1614OC
doi: 10.1164/rccm.200810-1614OC pubmed: 19644049
Goold null, Williams null, Arnold null (2000) Handling conflict in end-of-life care. JAMA 283:3199–3200
Higel T, Alaoui A, Bouton C, Fournier J-P (2019) Effect of living wills on end-of-life care: a systematic review. J Am Geriatr Soc 67:164–171. https://doi.org/10.1111/jgs.15630
doi: 10.1111/jgs.15630 pubmed: 30508301
Kon AA, Davidson JE, Morrison W et al (2016) Shared decision-making in intensive care units. Executive summary of the American college of critical care medicine and American thoracic society policy statement. Am J Respir Crit Care Med 193:1334–1336. https://doi.org/10.1164/rccm.201602-0269ED
doi: 10.1164/rccm.201602-0269ED pubmed: 27097019 pmcid: 4910896
Avidan A, Sprung CL, Schefold JC et al (2021) Variations in end-of-life practices in intensive care units worldwide (Ethicus-2): a prospective observational study. Lancet Respir Med 9:1101–1110. https://doi.org/10.1016/S2213-2600(21)00261-7
doi: 10.1016/S2213-2600(21)00261-7 pubmed: 34364537
Lobo SM, De Simoni FHB, Jakob SM et al (2017) Decision-making on withholding or withdrawing life support in the ICU: a worldwide perspective. Chest 152:321–329. https://doi.org/10.1016/j.chest.2017.04.176
doi: 10.1016/j.chest.2017.04.176 pubmed: 28483610
Mentzelopoulos SD, Chen S, Nates JL et al (2022) Derivation and performance of an end-of-life practice score aimed at interpreting worldwide treatment-limiting decisions in the critically ill. Crit Care Lond Engl 26:106. https://doi.org/10.1186/s13054-022-03971-9
doi: 10.1186/s13054-022-03971-9
Arnfeldt CM, Groenvold M, Johnsen AT et al (2022) Development of an advance directive “communication tool” relevant for patients with advanced cancer in six European countries: experiences from the ACTION trial. PLoS ONE 17:e0271919. https://doi.org/10.1371/journal.pone.0271919
doi: 10.1371/journal.pone.0271919 pubmed: 35901043 pmcid: 9333298
Curtis JR, Patrick DL, Caldwell E et al (1999) The quality of patient-doctor communication about end-of-life care: a study of patients with advanced AIDS and their primary care clinicians. AIDS Lond Engl 13:1123–1131
doi: 10.1097/00002030-199906180-00017
Michalsen A, Long AC, DeKeyser GF et al (2019) Interprofessional shared decision-making in the ICU: a systematic review and recommendations from an expert panel. Crit Care Med 47:1258–1266. https://doi.org/10.1097/CCM.0000000000003870
doi: 10.1097/CCM.0000000000003870 pubmed: 31169620
Chou W-C, Huang C-C, Hu T-H et al (2022) Associations between family satisfaction with end-of-life care and chart-derived, process-based quality indicators in intensive care units. J Palliat Med 25:368–375. https://doi.org/10.1089/jpm.2021.0304
doi: 10.1089/jpm.2021.0304 pubmed: 34491114
Mark NM, Rayner SG, Lee NJ, Curtis JR (2015) Global variability in withholding and withdrawal of life-sustaining treatment in the intensive care unit: a systematic review. Intensive Care Med 41:1572–1585. https://doi.org/10.1007/s00134-015-3810-5
doi: 10.1007/s00134-015-3810-5 pubmed: 25904183
Sprung CL, Rusinova K, Ranzani OT (2015) Variability in forgoing life-sustaining treatments: reasons and recommendations. Intensive Care Med 41:1679–1681. https://doi.org/10.1007/s00134-015-3868-0
doi: 10.1007/s00134-015-3868-0 pubmed: 26077065
Rao SR, Salins N, Joshi U et al (2022) Palliative and end-of-life care in intensive care units in low- and middle-income countries: a systematically constructed scoping review. J Crit Care 71:154115. https://doi.org/10.1016/j.jcrc.2022.154115
doi: 10.1016/j.jcrc.2022.154115 pubmed: 35907272
Phua J, Joynt GM, Nishimura M et al (2016) Withholding and withdrawal of life-sustaining treatments in low-middle-income versus high-income Asian countries and regions. Intensive Care Med 42:1118–1127. https://doi.org/10.1007/s00134-016-4347-y
doi: 10.1007/s00134-016-4347-y pubmed: 27071388
Phua J, Joynt GM, Nishimura M et al (2015) Withholding and withdrawal of life-sustaining treatments in intensive care units in Asia. JAMA Intern Med 175:363–371. https://doi.org/10.1001/jamainternmed.2014.7386
doi: 10.1001/jamainternmed.2014.7386 pubmed: 25581712
Azab SMS, Abdul-Rahman SA, Esmat IM (2022) Survey of end-of-life care in intensive care units in Ain Shams university hospitals, Cairo, Egypt. HEC Forum Interdiscip J Hosp Ethical Leg Issues 34:25–39. https://doi.org/10.1007/s10730-020-09423-7
doi: 10.1007/s10730-020-09423-7
Agrawal K, Garg R, Bhatnagar S (2019) Knowledge and awareness of end-of-life care among doctors working in intensive care units at a tertiary care center: a questionnaire-based study. Indian J Crit Care Med Peer-Rev Off Publ Indian Soc Crit Care Med 23:568–573. https://doi.org/10.5005/jp-journals-10071-23293
doi: 10.5005/jp-journals-10071-23293
Sengupta J, Chatterjee SC (2017) Dying in intensive care units of India: commentaries on policies and position papers on palliative and end-of-life care. J Crit Care 39:11–17. https://doi.org/10.1016/j.jcrc.2016.12.017
doi: 10.1016/j.jcrc.2016.12.017 pubmed: 28104546
Rafiq N, Arthur D, Rahim S et al (2021) Nurses’ perceptions about the dignity of intubated patients. Nurs Ethics 28:980–995. https://doi.org/10.1177/0969733020985268
doi: 10.1177/0969733020985268 pubmed: 33663278
Scheunemann LP, Ernecoff NC, Buddadhumaruk P et al (2019) Clinician-family communication about patients’ values and preferences in intensive care units. JAMA Intern Med 179:676–684. https://doi.org/10.1001/jamainternmed.2019.0027
doi: 10.1001/jamainternmed.2019.0027 pubmed: 30933293 pmcid: 6503570
Schenker Y, Crowley-Matoka M, Dohan D et al (2012) I don’t want to be the one saying “we should just let him die”: intrapersonal tensions experienced by surrogate decision makers in the ICU. J Gen Intern Med 27:1657–1665. https://doi.org/10.1007/s11606-012-2129-y
doi: 10.1007/s11606-012-2129-y pubmed: 23011253 pmcid: 3509291
Kodali S, Stametz RA, Bengier AC et al (2014) Family experience with intensive care unit care: association of self-reported family conferences and family satisfaction. J Crit Care 29:641–644. https://doi.org/10.1016/j.jcrc.2014.03.012
doi: 10.1016/j.jcrc.2014.03.012 pubmed: 24721388
White DB, Angus DC, Shields A-M et al (2018) A Randomized trial of a family-support intervention in intensive care units. N Engl J Med 378:2365–2375. https://doi.org/10.1056/NEJMoa1802637
doi: 10.1056/NEJMoa1802637 pubmed: 29791247
Azoulay E, Chevret S, Leleu G et al (2000) Half the families of intensive care unit patients experience inadequate communication with physicians. Crit Care Med 28:3044–3049
doi: 10.1097/00003246-200008000-00061 pubmed: 10966293
Kerckhoffs MC, Kant M, van Delden JJM et al (2019) Selecting and evaluating decision-making strategies in the intensive care unit: a systematic review. J Crit Care 51:39–45. https://doi.org/10.1016/j.jcrc.2019.01.029
doi: 10.1016/j.jcrc.2019.01.029 pubmed: 30738286
Frivold G, Dale B, Slettebø Å (2015) Family members’ experiences of being cared for by nurses and physicians in Norwegian intensive care units: a phenomenological hermeneutical study. Intensive Crit Care Nurs 31:232–240. https://doi.org/10.1016/j.iccn.2015.01.006
doi: 10.1016/j.iccn.2015.01.006 pubmed: 25737105
Kentish-Barnes N, Chevret S, Valade S et al (2022) A three-step support strategy for relatives of patients dying in the intensive care unit: a cluster randomised trial. Lancet 399:656–664. https://doi.org/10.1016/S0140-6736(21)02176-0
doi: 10.1016/S0140-6736(21)02176-0 pubmed: 35065008
Silverman H, Wilson T, Tisherman S et al (2022) Ethical decision-making climate, moral distress, and intention to leave among ICU professionals in a tertiary academic hospital center. BMC Med Ethics 23:45. https://doi.org/10.1186/s12910-022-00775-y
doi: 10.1186/s12910-022-00775-y pubmed: 35439950 pmcid: 9017406
Hamric AB, Blackhall LJ (2007) Nurse-physician perspectives on the care of dying patients in intensive care units: collaboration, moral distress, and ethical climate. Crit Care Med 35:422–429. https://doi.org/10.1097/01.CCM.0000254722.50608.2D
doi: 10.1097/01.CCM.0000254722.50608.2D pubmed: 17205001
Watts T, Sydor A, Whybrow D et al (2023) Registered Nurses’ and nursing students’ perspectives on moral distress and its effects: a mixed-methods systematic review and thematic synthesis. Nurs Open 10:6014–6032. https://doi.org/10.1002/nop2.1913
doi: 10.1002/nop2.1913 pubmed: 37458290 pmcid: 10416007
Neville TH, Wiley JF, Yamamoto MC et al (2015) Concordance of nurses and physicians on whether critical care patients are receiving futile treatment. Am J Crit Care Off Publ Am Assoc Crit-Care Nurses 24:403–410. https://doi.org/10.4037/ajcc2015476
doi: 10.4037/ajcc2015476
Van den Bulcke B, Metaxa V, Reyners AK et al (2020) Ethical climate and intention to leave among critical care clinicians: an observational study in 68 intensive care units across Europe and the United States. Intensive Care Med 46:46–56. https://doi.org/10.1007/s00134-019-05829-1
doi: 10.1007/s00134-019-05829-1 pubmed: 31690968
Curtis JR, Higginson IJ, White DB (2022) Integrating palliative care into the ICU: a lasting and developing legacy. Intensive Care Med 48:939–942. https://doi.org/10.1007/s00134-022-06729-7
doi: 10.1007/s00134-022-06729-7 pubmed: 35577992
Romano AM, Gade KE, Nielsen G et al (2017) Early Palliative care reduces end-of-life intensive care unit (ICU) use but not ICU course in patients with advanced cancer. Oncologist 22:318–323. https://doi.org/10.1634/theoncologist.2016-0227
doi: 10.1634/theoncologist.2016-0227 pubmed: 28220023 pmcid: 5344633
Haun MW, Estel S, Rücker G et al (2017) Early palliative care for adults with advanced cancer. Cochrane Database Syst Rev 6:CD011129. https://doi.org/10.1002/14651858.CD011129.pub2
doi: 10.1002/14651858.CD011129.pub2 pubmed: 28603881
Carson SS, Cox CE, Wallenstein S et al (2016) Effect of palliative care-led meetings for families of patients with chronic critical illness: a randomized clinical trial. JAMA 316:51–62. https://doi.org/10.1001/jama.2016.8474
doi: 10.1001/jama.2016.8474 pubmed: 27380343 pmcid: 5538801
Ma J, Chi S, Buettner B et al (2019) Early palliative care consultation in the medical ICU: a cluster randomized crossover trial. Crit Care Med 47:1707–1715. https://doi.org/10.1097/CCM.0000000000004016
doi: 10.1097/CCM.0000000000004016 pubmed: 31609772 pmcid: 6861688
Helgeson SA, Burnside RC, Robinson MT et al (2023) Early versus usual palliative care consultation in the intensive care unit. Am J Hosp Palliat Care 40:544–551. https://doi.org/10.1177/10499091221115732
doi: 10.1177/10499091221115732 pubmed: 35833450
Kamdar BB, Suri R, Suchyta MR et al (2020) Return to work after critical illness: a systematic review and meta-analysis. Thorax 75:17–27. https://doi.org/10.1136/thoraxjnl-2019-213803
doi: 10.1136/thoraxjnl-2019-213803 pubmed: 31704795
Babar A, Eilenfeld K, Alqaisi S et al (2021) Incorporating early palliative medicine consultation into daily morning huddle in the ICU. Crit Care Explor 3:e0459. https://doi.org/10.1097/CCE.0000000000000459
doi: 10.1097/CCE.0000000000000459 pubmed: 34235454 pmcid: 8238322
Bhangu JK, Young BT, Posillico S et al (2020) Goals of care discussions for the imminently dying trauma patient. J Surg Res 246:269–273. https://doi.org/10.1016/j.jss.2019.07.046
doi: 10.1016/j.jss.2019.07.046 pubmed: 31614324
Chang H-T, Jerng J-S, Chen D-R (2020) Reduction of healthcare costs by implementing palliative family conference with the decision to withdraw life-sustaining treatments. J Formos Med Assoc Taiwan Yi Zhi 119:34–41. https://doi.org/10.1016/j.jfma.2019.02.011
doi: 10.1016/j.jfma.2019.02.011 pubmed: 30876787
Kupensky DT, Emerick ES, Hileman BM, Chance EA (2020) The association of time to palliative medicine consultation on geriatric trauma outcomes. J Trauma Nurs Off J Soc Trauma Nurses 27:177–184. https://doi.org/10.1097/JTN.0000000000000508
doi: 10.1097/JTN.0000000000000508
Mehta A, Krishnasamy P, Chai E et al (2023) Lessons learned from an embedded palliative care model in the medical intensive care unit. J Pain Symptom Manage 65:e321–e327. https://doi.org/10.1016/j.jpainsymman.2022.12.011
doi: 10.1016/j.jpainsymman.2022.12.011 pubmed: 36584736
Pottash M, McCamey D, Groninger H et al (2020) Palliative care consultation and effect on length of stay in a tertiary-level neurological intensive care unit. Palliat Med Rep 1:161–165. https://doi.org/10.1089/pmr.2020.0051
doi: 10.1089/pmr.2020.0051 pubmed: 34223471 pmcid: 8241345
Tabibian BE, Salehani AA, Kuhn EN et al (2019) Transitioning the treatment paradigm: how early palliative care service involvement affects the end-of-life course for critically ill patients in the neuro-intensive care unit. J Palliat Med 22:489–492. https://doi.org/10.1089/jpm.2018.0428
doi: 10.1089/jpm.2018.0428 pubmed: 30489190
Rose L, Haslam L, Dale C et al (2013) Behavioral pain assessment tool for critically ill adults unable to self-report pain. Am J Crit Care Off Publ Am Assoc Crit-Care Nurses 22:246–255. https://doi.org/10.4037/ajcc2013200
doi: 10.4037/ajcc2013200
Guttormson JL, Khan B, Brodsky MB et al (2023) Symptom assessment for mechanically ventilated patients: principles and priorities: an official american thoracic society workshop Report. Ann Am Thorac Soc 20:491–498. https://doi.org/10.1513/AnnalsATS.202301-023ST
doi: 10.1513/AnnalsATS.202301-023ST pubmed: 37000144 pmcid: 10112406
Damico V, Cazzaniga F, Murano L et al (2018) Impact of a clinical therapeutic intervention on pain assessment, management, and nursing practices in an intensive care unit: a before-and-after study. Pain Manag Nurs Off J Am Soc Pain Manag Nurses 19:256–266. https://doi.org/10.1016/j.pmn.2018.01.007
doi: 10.1016/j.pmn.2018.01.007
Hamdan KM (2019) Nurses’ assessment practices of pain among critically ill patients. Pain Manag Nurs Off J Am Soc Pain Manag Nurses 20:489–496. https://doi.org/10.1016/j.pmn.2019.04.003
doi: 10.1016/j.pmn.2019.04.003
Kalfon P, Baumstarck K, Estagnasie P et al (2017) A tailored multicomponent program to reduce discomfort in critically ill patients: a cluster-randomized controlled trial. Intensive Care Med 43:1829–1840. https://doi.org/10.1007/s00134-017-4991-x
doi: 10.1007/s00134-017-4991-x pubmed: 29181557
Radtke FM, Heymann A, Franck M et al (2012) How to implement monitoring tools for sedation, pain and delirium in the intensive care unit: an experimental cohort study. Intensive Care Med 38:1974–1981. https://doi.org/10.1007/s00134-012-2658-1
doi: 10.1007/s00134-012-2658-1 pubmed: 22945432
Gélinas C, Arbour C, Michaud C et al (2013) Patients and ICU nurses’ perspectives of non-pharmacological interventions for pain management. Nurs Crit Care 18:307–318. https://doi.org/10.1111/j.1478-5153.2012.00531.x
doi: 10.1111/j.1478-5153.2012.00531.x pubmed: 24165072
Gélinas C, Arbour C, Michaud C et al (2011) Implementation of the critical-care pain observation tool on pain assessment/management nursing practices in an intensive care unit with nonverbal critically ill adults: a before and after study. Int J Nurs Stud 48:1495–1504. https://doi.org/10.1016/j.ijnurstu.2011.03.012
doi: 10.1016/j.ijnurstu.2011.03.012 pubmed: 21550048
Topolovec-Vranic J, Canzian S, Innis J et al (2010) Patient satisfaction and documentation of pain assessments and management after implementing the adult nonverbal pain scale. Am J Crit Care Off Publ Am Assoc Crit-Care Nurses 19:345–354. https://doi.org/10.4037/ajcc2010247
doi: 10.4037/ajcc2010247
Chanques G, Jaber S, Barbotte E et al (2006) Impact of systematic evaluation of pain and agitation in an intensive care unit. Crit Care Med 34:1691–1699. https://doi.org/10.1097/01.CCM.0000218416.62457.56
doi: 10.1097/01.CCM.0000218416.62457.56 pubmed: 16625136
Voigt L, Paice JA, Pouliot J (1995) Standardized pain flowsheet: impact on patient-reported pain experiences after cardiovascular surgery. Am J Crit Care Off Publ Am Assoc Crit-Care Nurses 4:308–313
Georgiou E, Hadjibalassi M, Lambrinou E et al (2015) The impact of pain assessment on critically ill patients’ outcomes: a systematic review. BioMed Res Int 2015:503830. https://doi.org/10.1155/2015/503830
doi: 10.1155/2015/503830 pubmed: 26558273 pmcid: 4628961
Payen J-F, Bosson J-L, Chanques G et al (2009) Pain assessment is associated with decreased duration of mechanical ventilation in the intensive care unit: a post Hoc analysis of the DOLOREA study. Anesthesiology 111:1308–1316. https://doi.org/10.1097/ALN.0b013e3181c0d4f0
doi: 10.1097/ALN.0b013e3181c0d4f0 pubmed: 19934877
Baumstarck K, Boucekine M, Estagnasie P et al (2019) Assessment of patients’’ self-perceived intensive care unit discomforts: validation of the 18-item version of the IPREA. Health Qual Life Outcomes 17:29. https://doi.org/10.1186/s12955-019-1101-5
doi: 10.1186/s12955-019-1101-5 pubmed: 30732654 pmcid: 6367827
Jodaki K, Abdi K, Mousavi M-S et al (2021) Effect of rosa damascene aromatherapy on anxiety and sleep quality in cardiac patients: a randomized controlled trial. Complement Ther Clin Pract 42:101299. https://doi.org/10.1016/j.ctcp.2020.101299
doi: 10.1016/j.ctcp.2020.101299 pubmed: 33395586
Leong RW, Davies LJ, Fook-Chong S et al (2021) Effect of the use of earplugs and eye masks on the quality of sleep after major abdominal surgery: a randomised controlled trial. Anaesthesia 76:1482–1491. https://doi.org/10.1111/anae.15468
doi: 10.1111/anae.15468 pubmed: 33881774
Altintaş S, Çelik S, Karahan E (2024) The effects of ergonomic sleep mask use on sleep quality and comfort in intensive care patients. J Sleep Res 33:e13966. https://doi.org/10.1111/jsr.13966
doi: 10.1111/jsr.13966 pubmed: 37332245
Obanor OO, McBroom MM, Elia JM et al (2021) The impact of earplugs and eye masks on sleep quality in surgical ICU patients at risk for frequent awakenings. Crit Care Med 49:e822–e832. https://doi.org/10.1097/CCM.0000000000005031
doi: 10.1097/CCM.0000000000005031 pubmed: 33870919
Alinia-Najjar R, Bagheri-Nesami M, Shorofi SA et al (2020) The effect of foot reflexology massage on burn-specific pain anxiety and sleep quality and quantity of patients hospitalized in the burn intensive care unit (ICU). Burns J Int Soc Burn Inj 46:1942–1951. https://doi.org/10.1016/j.burns.2020.04.035
doi: 10.1016/j.burns.2020.04.035
Gandolfi JV, Di Bernardo APA, Chanes DAV et al (2020) The effects of melatonin supplementation on sleep quality and assessment of the serum melatonin in ICU patients: a randomized controlled trial. Crit Care Med 48:e1286–e1293. https://doi.org/10.1097/CCM.0000000000004690
doi: 10.1097/CCM.0000000000004690 pubmed: 33048904
Robert R, Le Gouge A, Kentish-Barnes N et al (2017) Terminal weaning or immediate extubation for withdrawing mechanical ventilation in critically ill patients (the ARREVE observational study). Intensive Care Med. https://doi.org/10.1007/s00134-017-4891-0
doi: 10.1007/s00134-017-4891-0 pubmed: 29481014
Campbell ML, Yarandi HN, Mendez M (2015) A two-group trial of a terminal ventilator withdrawal algorithm: pilot testing. J Palliat Med 18:781–785. https://doi.org/10.1089/jpm.2015.0111
doi: 10.1089/jpm.2015.0111 pubmed: 26091245
Vink EE, Azoulay E, Caplan A et al (2018) Time-limited trial of intensive care treatment: an overview of current literature. Intensive Care Med 44:1369–1377. https://doi.org/10.1007/s00134-018-5339-x
doi: 10.1007/s00134-018-5339-x pubmed: 30136140
Quill TE, Holloway R (2011) Time-limited trials near the end of life. JAMA 306:1483–1484. https://doi.org/10.1001/jama.2011.1413
doi: 10.1001/jama.2011.1413 pubmed: 21972312
Hill SA, Dawood A, Boland E et al (2022) Palliative medicine in the intensive care unit: needs, delivery, quality. BMJ Support Palliat Care 12:38–41. https://doi.org/10.1136/bmjspcare-2020-002795
doi: 10.1136/bmjspcare-2020-002795
Adamski J, Weigl W, Musialowicz T et al (2022) Predictors of treatment limitations in Finnish intensive care units. Acta Anaesthesiol Scand 66:526–538. https://doi.org/10.1111/aas.14035
doi: 10.1111/aas.14035 pubmed: 35118641
Chavez G, Richman IB, Kaimal R et al (2018) Reversals and limitations on high-intensity, life-sustaining treatments. PLoS ONE 13:e0190569. https://doi.org/10.1371/journal.pone.0190569
doi: 10.1371/journal.pone.0190569 pubmed: 29489814 pmcid: 5830043
Benoit D, van der Zee E, Darmon M et al (2021) Outcomes of ICU patients with and without perceptions of excessive care: a comparison between cancer and non-cancer patients. Ann Intensive Care 11:120. https://doi.org/10.1186/s13613-021-00895-5
doi: 10.1186/s13613-021-00895-5 pubmed: 34331626 pmcid: 8325749
Turnbull AE, Ruhl AP, Lau BM et al (2014) Timing of limitations in life support in acute lung injury patients: a multisite study. Crit Care Med 42:296–302. https://doi.org/10.1097/CCM.0b013e3182a272db
doi: 10.1097/CCM.0b013e3182a272db pubmed: 23989178 pmcid: 3947055
Peñasco Y, González-Castro A, Rodríguez Borregán JC et al (2017) Limitation of life-sustaining treatment in severe trauma in the elderly after admission to an intensive care unit. Med Intensiva 41:394–400. https://doi.org/10.1016/j.medin.2017.03.009
doi: 10.1016/j.medin.2017.03.009 pubmed: 28528969
Xu HG, Kynoch K, Tuckett A, Eley R (2020) Effectiveness of interventions to reduce emergency department staff occupational stress and/or burnout: a systematic review. JBI Evid Synth 18:1156–1188. https://doi.org/10.11124/JBISRIR-D-19-00252
doi: 10.11124/JBISRIR-D-19-00252 pubmed: 32813371
Bocci MG, D’Alò C, Barelli R et al (2016) Taking Care of relationships in the intensive care unit: positive impact on family consent for organ donation. Transplant Proc 48:3245–3250. https://doi.org/10.1016/j.transproceed.2016.09.042
doi: 10.1016/j.transproceed.2016.09.042 pubmed: 27931564
Curtis JR, Treece PD, Nielsen EL et al (2008) Integrating palliative and critical care: evaluation of a quality-improvement intervention. Am J Respir Crit Care Med 178:269–275. https://doi.org/10.1164/rccm.200802-272OC
doi: 10.1164/rccm.200802-272OC pubmed: 18480429 pmcid: 2542424
Black MD, Vigorito MC, Curtis JR et al (2013) A multifaceted intervention to improve compliance with process measures for ICU clinician communication with ICU patients and families. Crit Care Med 41:2275–2283. https://doi.org/10.1097/CCM.0b013e3182982671
doi: 10.1097/CCM.0b013e3182982671 pubmed: 24060769
Curtis JR, Back AL, Ford DW et al (2013) Effect of communication skills training for residents and nurse practitioners on quality of communication with patients with serious illness: a randomized trial. JAMA 310:2271–2281. https://doi.org/10.1001/jama.2013.282081
doi: 10.1001/jama.2013.282081 pubmed: 24302090 pmcid: 4310457
Azoulay E, Pochard F, Chevret S et al (2001) Meeting the needs of intensive care unit patient families: a multicenter study. Am J Respir Crit Care Med 163:135–139. https://doi.org/10.1164/ajrccm.163.1.2005117
doi: 10.1164/ajrccm.163.1.2005117 pubmed: 11208638
Azoulay E, Pochard F, Chevret S et al (2002) Impact of a family information leaflet on effectiveness of information provided to family members of intensive care unit patients: a multicenter, prospective, randomized, controlled trial. Am J Respir Crit Care Med 165:438–442. https://doi.org/10.1164/ajrccm.165.4.200108-006oc
doi: 10.1164/ajrccm.165.4.200108-006oc pubmed: 11850333
Scheunemann LP, McDevitt M, Carson SS, Hanson LC (2011) Randomized, controlled trials of interventions to improve communication in intensive care: a systematic review. Chest 139:543–554. https://doi.org/10.1378/chest.10-0595
doi: 10.1378/chest.10-0595 pubmed: 21106660
Oczkowski SJW, Chung H-O, Hanvey L et al (2016) Communication tools for end-of-life decision-making in the intensive care unit: a systematic review and meta-analysis. Crit Care Lond Engl 20:97. https://doi.org/10.1186/s13054-016-1264-y
doi: 10.1186/s13054-016-1264-y
Lautrette A, Darmon M, Megarbane B et al (2007) A communication strategy and brochure for relatives of patients dying in the ICU. N Engl J Med 356:469–478. https://doi.org/10.1056/NEJMoa063446
doi: 10.1056/NEJMoa063446 pubmed: 17267907
Robin S, Labarriere C, Sechaud G et al (2021) Information pamphlet given to relatives during the end-of-life decision in the ICU: an assessor-blinded, randomized controlled trial. Chest 159:2301–2308. https://doi.org/10.1016/j.chest.2021.01.072
doi: 10.1016/j.chest.2021.01.072 pubmed: 33549600
Chiang VCL, Lee RLP, Ho MF et al (2017) Fulfilling the psychological and information need of the family members of critically ill patients using interactive mobile technology: a randomised controlled trial. Intensive Crit Care Nurs 41:77–83. https://doi.org/10.1016/j.iccn.2017.03.006
doi: 10.1016/j.iccn.2017.03.006 pubmed: 28438476
Greenberg JA, Basapur S, Quinn TV et al (2022) Daily written care summaries for families of critically ill patients: a randomized controlled trial. Crit Care Med 50:1296–1305. https://doi.org/10.1097/CCM.0000000000005583
doi: 10.1097/CCM.0000000000005583 pubmed: 35607975
Mistraletti G, Umbrello M, Mantovani ES et al (2017) A family information brochure and dedicated website to improve the ICU experience for patients’ relatives: an Italian multicenter before-and-after study. Intensive Care Med 43:69–79. https://doi.org/10.1007/s00134-016-4592-0
doi: 10.1007/s00134-016-4592-0 pubmed: 27830281
Amass T, Van Scoy LJ, Hua M et al (2022) Stress-related disorders of family members of patients admitted to the intensive care unit with COVID-19. JAMA Intern Med. https://doi.org/10.1001/jamainternmed.2022.1118
doi: 10.1001/jamainternmed.2022.1118 pubmed: 35467698 pmcid: 9039825
Azoulay E, Forel J, Vinatier I et al (2018) Questions to improve family-staff communication in the ICU: a randomized controlled trial. Intensive Care Med 44:1879–1887. https://doi.org/10.1007/s00134-018-5423-2
doi: 10.1007/s00134-018-5423-2 pubmed: 30374690
Danis M, Federman D, Fins JJ et al (1999) Incorporating palliative care into critical care education: principles, challenges, and opportunities. Crit Care Med 27:2005–2013. https://doi.org/10.1097/00003246-199909000-00047
doi: 10.1097/00003246-199909000-00047 pubmed: 10507632
Cohen R, Sprung CL (1999) Critical care education in the medical school curriculum. Crit Care Med 27:2068–2069. https://doi.org/10.1097/00003246-199909000-00080
doi: 10.1097/00003246-199909000-00080 pubmed: 10507664
Brown CE, Back AL, Ford DW et al (2018) Self-assessment scores improve after simulation-based palliative care communication skill workshops. Am J Hosp Palliat Care 35:45–51. https://doi.org/10.1177/1049909116681972
doi: 10.1177/1049909116681972 pubmed: 28273752
Darmon M, Ducos G, Coquet I et al (2016) Formal academic training on ethics may address junior physicians’’ needs. Chest 150:180–187. https://doi.org/10.1016/j.chest.2016.02.651
doi: 10.1016/j.chest.2016.02.651 pubmed: 26927524
Bassah N, Cox K, Seymour J (2016) A qualitative evaluation of the impact of a palliative care course on preregistration nursing students’ practice in cameroon. BMC Palliat Care 15:37. https://doi.org/10.1186/s12904-016-0106-7
doi: 10.1186/s12904-016-0106-7 pubmed: 27036409 pmcid: 4815205
Schwartz J, Schallenburger M, Tenge T et al (2022) Palliative care e-learning for physicians caring for critically ill and dying patients during the COVID-19 pandemic: an outcome evaluation with self-assessed knowledge and attitude. Int J Environ Res Public Health 19:12377. https://doi.org/10.3390/ijerph191912377
doi: 10.3390/ijerph191912377 pubmed: 36231676 pmcid: 9564513
Engelberg R, Downey L, Curtis JR (2006) Psychometric characteristics of a quality of communication questionnaire assessing communication about end-of-life care. J Palliat Med 9:1086–1098. https://doi.org/10.1089/jpm.2006.9.1086
doi: 10.1089/jpm.2006.9.1086 pubmed: 17040146
Kyeremanteng K, Gagnon L-P, Thavorn K et al (2018) The impact of palliative care consultation in the ICU on length of stay: a systematic review and cost evaluation. J Intensive Care Med 33:346–353. https://doi.org/10.1177/0885066616664329
doi: 10.1177/0885066616664329 pubmed: 27582396
Tanaka Y, Masukawa K, Kawashima A et al (2023) Quality indicators for palliative care in intensive care units: a systematic review. Ann Palliat Med 12:584–599. https://doi.org/10.21037/apm-22-1005
doi: 10.21037/apm-22-1005 pubmed: 37038065
Kaufer M, Murphy P, Barker K, Mosenthal A (2008) Family satisfaction following the death of a loved one in an inner city MICU. Am J Hosp Palliat Care 25:318–325. https://doi.org/10.1177/1049909108319262
doi: 10.1177/1049909108319262 pubmed: 18539762
McCormick AJ, Curtis JR, Stowell-Weiss P et al (2010) Improving social work in intensive care unit palliative care: results of a quality improvement intervention. J Palliat Med 13:297–304. https://doi.org/10.1089/jpm.2009.0204
doi: 10.1089/jpm.2009.0204 pubmed: 20078245 pmcid: 2883820
Aslakson R, Cheng J, Vollenweider D et al (2014) Evidence-based palliative care in the intensive care unit: a systematic review of interventions. J Palliat Med 17:219–235. https://doi.org/10.1089/jpm.2013.0409
doi: 10.1089/jpm.2013.0409 pubmed: 24517300 pmcid: 3924791
Curtis JR, Engelberg RA, Wenrich MD et al (2002) Studying communication about end-of-life care during the ICU family conference: development of a framework. J Crit Care 17:147–160
doi: 10.1053/jcrc.2002.35929 pubmed: 12297990
Lautrette A, Ciroldi M, Ksibi H, Azoulay E (2006) End-of-life family conferences: rooted in the evidence. Crit Care Med 34:S364-372. https://doi.org/10.1097/01.CCM.0000237049.44246.8C
doi: 10.1097/01.CCM.0000237049.44246.8C pubmed: 17057600
Rosa RG, Falavigna M, da Silva DB et al (2019) Effect of flexible family visitation on delirium among patients in the intensive care unit: the ICU visits randomized clinical trial. JAMA 322:216–228. https://doi.org/10.1001/jama.2019.8766
doi: 10.1001/jama.2019.8766 pubmed: 31310297 pmcid: 6635909
Chapman DK, Collingridge DS, Mitchell LA et al (2016) Satisfaction with elimination of all visitation restrictions in a mixed-profile intensive care unit. Am J Crit Care Off Publ Am Assoc Crit-Care Nurses 25:46–50. https://doi.org/10.4037/ajcc2016789
doi: 10.4037/ajcc2016789
Nassar Junior AP, Besen BAMP, Robinson CC et al (2018) Flexible versus restrictive visiting policies in ICUS: a systematic review and meta-analysis. Crit Care Med 46:1175–1180. https://doi.org/10.1097/CCM.0000000000003155
doi: 10.1097/CCM.0000000000003155 pubmed: 29642108
Schnell D, Abadie S, Toullic P et al (2013) Open visitation policies in the ICU: experience from relatives and clinicians. Intensive Care Med 39:1873–1874. https://doi.org/10.1007/s00134-013-2956-2
doi: 10.1007/s00134-013-2956-2 pubmed: 23695268
Mitchell ML, Aitken LM (2017) Flexible visiting positively impacted on patients, families and staff in an Australian Intensive Care Unit: a before-after mixed method study. Aust Crit Care Off J Confed Aust Crit Care Nurses 30:91–97. https://doi.org/10.1016/j.aucc.2016.01.001
doi: 10.1016/j.aucc.2016.01.001
Baharoon S, Al Yafi W, Al Qurashi A et al (2017) Family satisfaction in critical care units: does an open visiting hours policy have an impact? J Patient Saf 13:169–174. https://doi.org/10.1097/PTS.0000000000000140
doi: 10.1097/PTS.0000000000000140 pubmed: 25136852
Giannini A, Garrouste-Orgeas M, Latour JM (2014) What’s new in ICU visiting policies: can we continue to keep the doors closed? Intensive Care Med 40:730–733. https://doi.org/10.1007/s00134-014-3267-y
doi: 10.1007/s00134-014-3267-y pubmed: 24687297
Davidson J, Aslakson R, Long A et al (2017) Guidelines for family-centered care in the neonatal, pediatric, and adult ICU. Crit Care Med 45:103–128. https://doi.org/10.1097/CCM.0000000000002169
doi: 10.1097/CCM.0000000000002169 pubmed: 27984278
Afzali Rubin M, Svensson TL, Herling SF et al (2023) Family presence during resuscitation. Cochrane Database Syst Rev 5:CD013619. https://doi.org/10.1002/14651858.CD013619.pub2
doi: 10.1002/14651858.CD013619.pub2 pubmed: 37159193
Fulbrook P, Latour J, Albarran J et al (2007) The presence of family members during cardiopulmonary resuscitation: European federation of critical care nursing associations, European society of paediatric and neonatal intensive care and European society of cardiology council on cardiovascular nursing and allied professions joint position statement. Nurs Crit Care 12:250–252. https://doi.org/10.1111/j.1478-5153.2007.00240.x
doi: 10.1111/j.1478-5153.2007.00240.x pubmed: 17883618
Pattison NA, White C, Lone NI (2021) Bereavement in critical care: a narrative review and practice exploration of current provision of support services and future challenges. J Intensive Care Soc 22:349–356. https://doi.org/10.1177/1751143720928898
doi: 10.1177/1751143720928898 pubmed: 35154374
Kentish-Barnes N, Cohen-Solal Z, Souppart V et al (2017) “It was the only thing i could hold onto, but…”: receiving a letter of condolence after loss of a loved one in the ICU: a qualitative study of bereaved relatives’’ experience. Crit Care Med 45:1965–1971. https://doi.org/10.1097/CCM.0000000000002687
doi: 10.1097/CCM.0000000000002687 pubmed: 28857855
Kentish-Barnes N, Chevret S, Champigneulle B et al (2017) Effect of a condolence letter on grief symptoms among relatives of patients who died in the ICU: a randomized clinical trial. Intensive Care Med 43:473–484. https://doi.org/10.1007/s00134-016-4669-9
doi: 10.1007/s00134-016-4669-9 pubmed: 28197680
Kock M, Berntsson C, Bengtsson A (2014) A follow-up meeting post death is appreciated by family members of deceased patients. Acta Anaesthesiol Scand 58:891–896. https://doi.org/10.1111/aas.12358
doi: 10.1111/aas.12358 pubmed: 24981404
Binette E, Elwell J, Parekh de Campos A, Anderson RV (2023) Show and tell: photography and storytelling to better understand the end-of-life experience of families in the intensive care unit. Omega. https://doi.org/10.1177/00302228231190957
doi: 10.1177/00302228231190957 pubmed: 37496111
Johansson M, Wåhlin I, Magnusson L et al (2018) Family members’ experiences with intensive care unit diaries when the patient does not survive. Scand J Caring Sci 32:233–240. https://doi.org/10.1111/scs.12454
doi: 10.1111/scs.12454 pubmed: 28524380
Coventry A, Gerdtz M, McInnes E et al (2023) Supporting families of patients who die in adult intensive care: a scoping review of interventions. Intensive Crit Care Nurs 78:103454. https://doi.org/10.1016/j.iccn.2023.103454
doi: 10.1016/j.iccn.2023.103454 pubmed: 37253283
Bazzano G, Buccoliero F, Villa M et al (2023) The role of intensive care unit diaries in the grieving process: a monocentric qualitative study. Nurs Crit Care. https://doi.org/10.1111/nicc.13012
doi: 10.1111/nicc.13012 pubmed: 38015002
Moss SJ, Wollny K, Poulin TG et al (2021) Bereavement interventions to support informal caregivers in the intensive care unit: a systematic review. BMC Palliat Care 20:66. https://doi.org/10.1186/s12904-021-00763-w
doi: 10.1186/s12904-021-00763-w pubmed: 33980242 pmcid: 8117265
Riegel M, Randall S, Buckley T (2019) Memory making in end-of-life care in the adult intensive care unit: a scoping review of the research literature. Aust Crit Care Off J Confed Aust Crit Care Nurses 32:442–447. https://doi.org/10.1016/j.aucc.2018.12.002
doi: 10.1016/j.aucc.2018.12.002
Santiago C, Lee C, Piacentino R et al (2017) A pilot study of an interprofessional, multi-component bereavement follow-up program in the intensive care unit. Can J Crit Care Nurs 28:18–24
Vanstone M, Toledo F, Clarke F et al (2016) Narrative medicine and death in the ICU: word clouds as a visual legacy. BMJ Support Palliat Care. https://doi.org/10.1136/bmjspcare-2016-001179
doi: 10.1136/bmjspcare-2016-001179 pubmed: 27884867
Efstathiou N, Walker W, Metcalfe A, Vanderspank-Wright B (2019) The state of bereavement support in adult intensive care: a systematic review and narrative synthesis. J Crit Care 50:177–187. https://doi.org/10.1016/j.jcrc.2018.11.026
doi: 10.1016/j.jcrc.2018.11.026 pubmed: 30553185
Hetland BD, McAndrew NS, Kupzyk KA et al (2022) Family caregiver preferences and contributions related to patient care in the ICU. West J Nurs Res 44:214–226. https://doi.org/10.1177/01939459211062954
doi: 10.1177/01939459211062954 pubmed: 34904483
Amass TH, Villa G, OMahony S et al (2020) Family care rituals in the icu to reduce symptoms of post-traumatic stress disorder in family members-a multicenter, multinational, before-and-after intervention trial. Crit Care Med 48:176–184. https://doi.org/10.1097/CCM.0000000000004113
doi: 10.1097/CCM.0000000000004113 pubmed: 31939785 pmcid: 7147959
Rose L, Yu L, Casey J et al (2021) Communication and Virtual visiting for families of patients in intensive care during COVID-19: a UK National Survey. Ann Am Thorac Soc. https://doi.org/10.1513/AnnalsATS.202012-1500OC
doi: 10.1513/AnnalsATS.202012-1500OC pubmed: 33617747 pmcid: 8522289
Kentish-Barnes N, Cohen-Solal Z, Morin L et al (2021) Lived experiences of family members of patients with severe COVID-19 who died in intensive care units in France. JAMA Netw Open 4:e2113355. https://doi.org/10.1001/jamanetworkopen.2021.13355
doi: 10.1001/jamanetworkopen.2021.13355 pubmed: 34152418 pmcid: 8218069
Cox C, Olsen O, Parish A et al (2022) Palliative care phenotypes among critically ill patients and family members: intensive care unit prospective cohort study. BMJ Support Palliat Care. https://doi.org/10.1136/spcare-2022-003622
doi: 10.1136/spcare-2022-003622 pubmed: 36167642 pmcid: 10085460
Ashana DC, Welsh W, Preiss D et al (2024) Racial differences in shared decision-making about critical illness. JAMA Intern Med 184:424–432. https://doi.org/10.1001/jamainternmed.2023.8433
doi: 10.1001/jamainternmed.2023.8433 pubmed: 38407845
Brooks LA, Bloomer MJ, Manias E (2019) Culturally sensitive communication at the end-of-life in the intensive care unit: a systematic review. Aust Crit Care Off J Confed Aust Crit Care Nurses 32:516–523. https://doi.org/10.1016/j.aucc.2018.07.003
doi: 10.1016/j.aucc.2018.07.003
Long AC, Engelberg RA, Downey L et al (2014) Race, income, and education: associations with patient and family ratings of end-of-life care and communication provided by physicians-in-training. J Palliat Med 17:435–447. https://doi.org/10.1089/jpm.2013.0214
doi: 10.1089/jpm.2013.0214 pubmed: 24592958 pmcid: 3991967
Lee JJ, Long AC, Curtis JR, Engelberg RA (2016) The influence of race/ethnicity and education on family ratings of the quality of dying in the ICU. J Pain Symptom Manage 51:9–16. https://doi.org/10.1016/j.jpainsymman.2015.08.008
doi: 10.1016/j.jpainsymman.2015.08.008 pubmed: 26384556
Cox CE, Ashana DC, Riley IL et al (2024) Mobile application-based communication facilitation platform for family members of critically ill patients: a randomized clinical trial. JAMA Netw Open 7:e2349666. https://doi.org/10.1001/jamanetworkopen.2023.49666
doi: 10.1001/jamanetworkopen.2023.49666 pubmed: 38175648 pmcid: 10767607
McAndrew NS, Schiffman R, Leske J (2019) Relationships among climate of care, nursing family care and family well-being in ICUs. Nurs Ethics 26:2494–2510. https://doi.org/10.1177/0969733019826396
doi: 10.1177/0969733019826396 pubmed: 30832534
Schwarzkopf D, Westermann I, Skupin H et al (2015) A novel questionnaire to measure staff perception of end-of-life decision making in the intensive care unit–development and psychometric testing. J Crit Care 30:187–195. https://doi.org/10.1016/j.jcrc.2014.09.015
doi: 10.1016/j.jcrc.2014.09.015 pubmed: 25311265
Brooks LA, Manias E, Nicholson P (2017) Communication and decision-making about end-of-life care in the intensive care unit. Am J Crit Care Off Publ Am Assoc Crit-Care Nurses 26:336–341. https://doi.org/10.4037/ajcc2017774
doi: 10.4037/ajcc2017774
Poi CH, Khoo HS, Ang S-L et al (2023) Palliative care integration in the intensive care unit: healthcare professionals’ perspectives - a qualitative study. BMJ Support Palliat Care. https://doi.org/10.1136/spcare-2022-003789
doi: 10.1136/spcare-2022-003789 pubmed: 36690416
Vincent J, Boulanger C, van Mol M et al (2022) Ten areas for ICU clinicians to be aware of to help retain nurses in the ICU. Crit Care 26:310. https://doi.org/10.1186/s13054-022-04182-y
doi: 10.1186/s13054-022-04182-y pubmed: 36229859 pmcid: 9559151
Flannery L, Ramjan LM, Peters K (2016) End-of-life decisions in the Intensive Care Unit (ICU) - exploring the experiences of ICU nurses and doctors - a critical literature review. Aust Crit Care Off J Confed Aust Crit Care Nurses 29:97–103. https://doi.org/10.1016/j.aucc.2015.07.004
doi: 10.1016/j.aucc.2015.07.004
Moss M, Good VS, Gozal D et al (2016) An official critical care societies collaborative statement-burnout syndrome in critical care health-care professionals: a call for action. Chest 150:17–26. https://doi.org/10.1016/j.chest.2016.02.649
doi: 10.1016/j.chest.2016.02.649 pubmed: 27396776
Boulton AJ, Slowther A-M, Yeung J, Bassford C (2023) Moral distress among intensive care unit professions in the UK: a mixed-methods study. BMJ Open 13:e068918. https://doi.org/10.1136/bmjopen-2022-068918
doi: 10.1136/bmjopen-2022-068918 pubmed: 37185186 pmcid: 10151959
Giabicani M, Arditty L, Mamzer M-F et al (2023) Team-family conflicts over end-of-life decisions in ICU: a survey of French physicians’ beliefs. PLoS ONE 18:e0284756. https://doi.org/10.1371/journal.pone.0284756
doi: 10.1371/journal.pone.0284756 pubmed: 37098023 pmcid: 10128920
Spijkers AS, Akkermans A, Smets EMA et al (2022) How doctors manage conflicts with families of critically ill patients during conversations about end-of-life decisions in neonatal, pediatric, and adult intensive care. Intensive Care Med 48:910–922. https://doi.org/10.1007/s00134-022-06771-5
doi: 10.1007/s00134-022-06771-5 pubmed: 35773499 pmcid: 9273549
Papazian L, Hraiech S, Loundou A et al (2023) High-level burnout in physicians and nurses working in adult ICUs: a systematic review and meta-analysis. Intensive Care Med. https://doi.org/10.1007/s00134-023-07025-8
doi: 10.1007/s00134-023-07025-8 pubmed: 37326646 pmcid: 10354163
Azoulay E, Pochard F, Reignier J et al (2021) Symptoms of mental health disorders in critical care physicians facing the second COVID-19 wave: a cross-sectional study. Chest 160:944–955. https://doi.org/10.1016/j.chest.2021.05.023
doi: 10.1016/j.chest.2021.05.023 pubmed: 34023323
Leiter MP, Maslach C (2016) Latent burnout profiles: a new approach to understanding the burnout experience. Burn Res 3:89–100. https://doi.org/10.1016/j.burn.2016.09.001
doi: 10.1016/j.burn.2016.09.001
Embriaco N, Papazian L, Kentish-Barnes N et al (2007) Burnout syndrome among critical care healthcare workers. Curr Opin Crit Care 13:482–488. https://doi.org/10.1097/MCC.0b013e3282efd28a
doi: 10.1097/MCC.0b013e3282efd28a pubmed: 17762223
Azoulay E, De Waele J, Ferrer R et al (2020) Symptoms of burnout in intensive care unit specialists facing the COVID-19 outbreak. Ann Intensive Care 10:110. https://doi.org/10.1186/s13613-020-00722-3
doi: 10.1186/s13613-020-00722-3 pubmed: 32770449 pmcid: 7414284
Kok N, Van Gurp J, van der Hoeven JG et al (2023) Complex interplay between moral distress and other risk factors of burnout in ICU professionals: findings from a cross-sectional survey study. BMJ Qual Saf 32:225–234. https://doi.org/10.1136/bmjqs-2020-012239
doi: 10.1136/bmjqs-2020-012239 pubmed: 34187883
Burghi G, Lambert J, Chaize M et al (2014) Prevalence, risk factors and consequences of severe burnout syndrome in ICU. Intensive Care Med 40:1785–1786. https://doi.org/10.1007/s00134-014-3454-x
doi: 10.1007/s00134-014-3454-x pubmed: 25164397
Alvarez C (2020) Replenish at work: an integrative program to decrease stress and promote a culture of wellness in the intensive care unit. Crit Care Nurs Clin North Am 32:369–381. https://doi.org/10.1016/j.cnc.2020.05.001
doi: 10.1016/j.cnc.2020.05.001 pubmed: 32773179
Quenot JP, Rigaud JP, Prin S et al (2012) Suffering among carers working in critical care can be reduced by an intensive communication strategy on end-of-life practices. Intensive Care Med 38:55–61. https://doi.org/10.1007/s00134-011-2413-z
doi: 10.1007/s00134-011-2413-z pubmed: 22127481
Poncet M, Toullic P, Papazian L et al (2007) Burnout syndrome in critical care nursing staff. Am J Respir Crit Care Med 175:698–704. https://doi.org/10.1164/rccm.200606-806OC
doi: 10.1164/rccm.200606-806OC pubmed: 17110646

Auteurs

Jozef Kesecioglu (J)

Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands. j.kesecioglu@umcutrecht.nl.

Katerina Rusinova (K)

Department of Palliative Medicine, 1st Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czechia.

Daniela Alampi (D)

Sapienza University of Rome, A.O.U. Sant'Andrea, Rome, Italy.

Yaseen M Arabi (YM)

Intensive Care Department, King Saud Bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia.

Julie Benbenishty (J)

Faculty of Medicine, School of Nursing, Hebrew University, Jerusalem, Israel.

Dominique Benoit (D)

Department of Intensive Care Medicine, Ghent University Hospital, Ghent, Belgium.
Faculty of Medicine and Health Science, Ghent University, Ghent, Belgium.

Carole Boulanger (C)

Royal Devon University NHS Foundation Trust, Exeter, UK.

Maurizio Cecconi (M)

Biomedical Sciences Department, Humanitas University, Milan, Italy.
Department of Anaesthesia and Intensive Care, IRCCS Humanitas Research Hospital, Milan, Italy.

Christopher Cox (C)

Division of Pulmonary and Critical Care Medicine, Duke University, Durham, NC, USA.

Marjel van Dam (M)

Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

Diederik van Dijk (D)

Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

James Downar (J)

Department of Medicine, University of Ottawa, Ottawa, Canada.
Bruyere Research Institute, Ottawa, Canada.

Nikolas Efstathiou (N)

School of Nursing and Midwifery, University of Birmingham, Birmingham, UK.

Ruth Endacott (R)

National Institute for Health and Care Research, London, UK.

Alessandro Galazzi (A)

Department of Medicine, University of Udine, Udine, Italy.

Fiona van Gelder (F)

Gelderse Vallei Hospital, Ede, The Netherlands.

Rik T Gerritsen (RT)

Centrum Voor Intensive Care, Medisch Centrum Leeuwarden, Leeuwarden, The Netherlands.

Armand Girbes (A)

Department of Critical Care, AmsterdamUMC Location VUmc, Amsterdam, The Netherlands.

Laura Hawyrluck (L)

Interdepartmental Division Critical Care Medicine, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Canada.

Margaret Herridge (M)

Critical Care and Respiratory Medicine, University Health Network, Toronto General Research Institute, Toronto, Canada.
Institute of Medical Sciences, Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.

Jan Hudec (J)

Department of Anaesthesiology and Intensive Care Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czechia.
Department of Simulation Medicine, Faculty of Medicine, Masaryk University, Brno, Czechia.

Nancy Kentish-Barnes (N)

Famiréa Research Group, APHP Nord, Saint Louis Hospital, Intensive Care Unit, Paris, France.

Monika Kerckhoffs (M)

Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

Jos M Latour (JM)

School of Nursing and Midwifery, Faculty of Health, University of Plymouth, Plymouth, UK.
Curtin School of Nursing, Curtin University, Perth, Australia.
Department of Nursing, Zhongshan Hospital, Fudan University, Shanghai, China.

Jan Malaska (J)

Department of Simulation Medicine, Faculty of Medicine, Masaryk University, Brno, Czechia.
Department of Paediatric Anaesthesiology and Intensive Care Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czechia.
Second Department of Anaesthesiology and Intensive Care Medicine, University Hospital Brno, Brno, Czechia.

Annachiara Marra (A)

Department of Neuroscience, Reproductive Science and Dentistry, University of Naples, Naples, Italy.

Stephanie Meddick-Dyson (S)

Wolfson Palliative Care Research Centre, Hull York, Medical School, University of Hull, Hull, UK.

Spyridon Mentzelopoulos (S)

First Department of Intensive Care Medicine, National and Kapodistrian University of Athens Medical School, Evaggelismos General Hospital, Athens, Greece.

Mervyn Mer (M)

Department of Medicine, Divisions of Critical Care and Pulmonology, Charlotte Maxeke Johannesburg Academic Hospital (CMJAH), Johannesburg, South Africa.
Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Victoria Metaxa (V)

Department of Critical Care, King's College Hospital NHS Foundation Trust, London, UK.
King's College London, London, UK.

Andrej Michalsen (A)

Department of Anesthesiology, Critical Care, Emergency Medicine and Pain Therapy, Konstanz Hospital, Constance, Germany.

Rajesh Mishra (R)

Ahmedabad Shaibya Comprehensive Care Clinic, Ahmedabad, India.

Giovanni Mistraletti (G)

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
S.C. Anesthesia and Intensive Care, Legnano Hospital, ASST Ovest Milanese, Milan, Italy.

Margo van Mol (M)

Department of Intensive Care Adults, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands.

Rui Moreno (R)

Hospital de São José, Unidade Local de Saúde São José, Lisbon, Portugal.
Faculdade de Ciências Médicas de Lisboa, Nova Medical School, Centro Clínico Académico de Lisboa, Lisbon, Portugal.
Faculdade de Ciências da Saúde, Universidade da Beira Interior, Covilhã, Portugal.

Judith Nelson (J)

Memorial Hospital, Weill Cornell Medical College, New York, NY, USA.

Andrea Ortiz Suñer (AO)

Hospital Arnau de Vilanova-Lliria, Valencia, Spain.
Universidad Católica de Valencia San Vicente Mártir, Valencia, Spain.

Natalie Pattison (N)

University of Hertfordshire, East and North Hertfordshire NHS Trust, Hatfield, UK.
Imperial Healthcare NHS Trust, Imperial College, London, UK.

Tereza Prokopova (T)

Department of Anaesthesiology and Intensive Care Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czechia.
Department of Simulation Medicine, Faculty of Medicine, Masaryk University, Brno, Czechia.

Kathleen Puntillo (K)

School of Nursing, University of California, San Francisco, San Francisco, CA, USA.

Kathryn Puxty (K)

Intensive Care, Glasgow Royal Infirmary, Glasgow, UK.
University of Glasgow, Glasgow, UK.

Samah Al Qahtani (SA)

Intensive Care Department, King Saud Bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia.

Lukas Radbruch (L)

Department of Palliative Medicine, University Hospital Bonn, Bonn, Germany.

Emilio Rodriguez-Ruiz (E)

Department of Intensive Care Medicine, University Clinic Hospital of Santiago de Compostela (CHUS), Galician Public Health System (SERGAS), Santiago de Compostela, Spain.
Simulation, Life Support and Intensive Care Research Unit of Santiago de Compostela (SICRUS), Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain.
CLINURSID Research Group, University of Santiago de Compostela, Santiago de Compostela, Spain.

Ron Sabar (R)

Sabar Health, Netanya, Israel.

Stefan J Schaller (SJ)

Department of Anaesthesiology and Intensive Care Medicine (CCM/CVK), Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Germany.

Shahla Siddiqui (S)

Department of Anesthesia Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Charles L Sprung (CL)

Department of Anesthesiology, Critical Care Medicine and Pain, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.

Michele Umbrello (M)

S.C. Anesthesia and Intensive Care, Legnano Hospital, ASST Ovest Milanese, Milan, Italy.

Marco Vergano (M)

Department of Anesthesia, Intensive Care and Emergency, San Giovanni Bosco Hospital, Turin, Italy.

Massimo Zambon (M)

Anesthesia and Intensive Care Ospedale "Uboldo", Cernusco sul Naviglio, Milan, Italy.

Marieke Zegers (M)

Department of Intensive Care, Radboud University Medical Center, Nijmegen, The Netherlands.

Michael Darmon (M)

Médecine Intensive et Réanimation, APHP, Saint-Louis Hospital, Paris, France.
Université Paris Cité, Paris, France.

Elie Azoulay (E)

Médecine Intensive et Réanimation, APHP, Saint-Louis Hospital, Paris, France.
Université Paris Cité, Paris, France.

Classifications MeSH