Type V Collagen Exhibits Distinct Regulatory Activities in TMJ Articular Disc versus Condylar Cartilage During Postnatal Growth and Remodeling.

Type V collagen extracellular matrix fibrocartilage mechanobiology temporomandibular joint

Journal

Acta biomaterialia
ISSN: 1878-7568
Titre abrégé: Acta Biomater
Pays: England
ID NLM: 101233144

Informations de publication

Date de publication:
01 Oct 2024
Historique:
received: 12 02 2024
revised: 02 09 2024
accepted: 26 09 2024
medline: 4 10 2024
pubmed: 4 10 2024
entrez: 3 10 2024
Statut: aheadofprint

Résumé

Understanding matrix molecular activities that regulate the postnatal growth and remodeling of temporomandibular joint (TMJ) condylar cartilage and articular disc will enable the development of effective regenerative strategies targeting TMJ disorder. This study elucidated the distinct roles of type V collagen (collagen V) in regulating these two units. Studying the TMJ of young adult Col5a1

Identifiants

DOI: 10.1016/j.actbio.2024.09.046 PMID: 39362448
pubmed: 39362448
pii: S1742-7061(24)00573-7
doi: 10.1016/j.actbio.2024.09.046
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024. Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

Declaration of competing interests The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Prashant Chandrasekaran (P)

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, United States.

Abdulaziz Alanazi (A)

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, United States.

Bryan Kwok (B)

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, United States.

Qing Li (Q)

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, United States.

Girish Viraraghavan (G)

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, United States.

Sriram Balasubramanian (S)

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, United States.

David B Frank (DB)

Penn-CHOP Lung Biology Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States; Division of Pediatric Cardiology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States.

X Lucas Lu (XL)

Department of Mechanical Engineering, University of Delaware, Newark, DE 19716, United States.

David E Birk (DE)

Department of Molecular Pharmacology and Physiology, Morsani School of Medicine, University of South Florida, Tampa, FL 33612, United States.

Robert L Mauck (RL)

McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States; Translational Musculoskeletal Research Center, Corporal Michael J. Crescenz Veterans Administration Medical Center, Philadelphia, PA 19104, United States.

Nathaniel A Dyment (NA)

McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States.

Eiki Koyama (E)

Department of Surgery, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States.

Lin Han (L)

School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, United States. Electronic address: lh535@drexel.edu.

Classifications MeSH