vSPACE: Exploring virtual spatial representation of articular chondrocytes at the Single-Cell level.
Journal
Bioinformatics (Oxford, England)
ISSN: 1367-4811
Titre abrégé: Bioinformatics
Pays: England
ID NLM: 9808944
Informations de publication
Date de publication:
03 Oct 2024
03 Oct 2024
Historique:
received:
18
03
2024
revised:
30
07
2024
accepted:
02
10
2024
medline:
4
10
2024
pubmed:
4
10
2024
entrez:
4
10
2024
Statut:
aheadofprint
Résumé
VSPACE is a web-based application presenting a spatial representation of scRNAseq data obtained from human articular cartilage by emulating the concept of spatial transcriptomics technology, but virtually. This virtual 2D plot presentation of human articular cartage cells generates several zonal distribution patterns, for one or multiple genes at a time, revealing patterns that scientists can appreciate as imputed spatial distribution patterns along the zonal axis. VSPACE is implemented in Python Dash as a web-based toolbox designed for data visualization of zonal gene expression patterns in articular cartilage chondrocytes. This tool is freely accessible at: Https://vspace.cse.uconn.edu/The source code and extra materials for this service can be downloaded from: Https://github.com/zhacheny/vSPACE. Dong-Guk Shin*: dong.shin@uconn.edu. Supplementary data are available at Bioinformatics online.
Identifiants
pubmed: 39363499
pii: 7810443
doi: 10.1093/bioinformatics/btae568
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© The Author(s) 2024. Published by Oxford University Press.