Downregulation of chemokine (C‑C motif) ligand 5 induced by a novel 8‑hydroxyquinoline derivative (91b1) suppresses tumor invasiveness in esophageal carcinoma.


Journal

International journal of molecular medicine
ISSN: 1791-244X
Titre abrégé: Int J Mol Med
Pays: Greece
ID NLM: 9810955

Informations de publication

Date de publication:
Dec 2024
Historique:
received: 05 04 2024
accepted: 06 08 2024
medline: 4 10 2024
pubmed: 4 10 2024
entrez: 4 10 2024
Statut: ppublish

Résumé

Esophageal squamous cell carcinoma (ESCC) is a particularly aggressive form of cancer with high mortality. In the present study, a novel 8‑hydroxyquinoline derivative (91b1) was investigated for its anticancer activities in ESCC along with its associated mechanisms. The

Identifiants

pubmed: 39364750
doi: 10.3892/ijmm.2024.5435
pii: 111
doi:
pii:

Substances chimiques

Chemokine CCL5 0
Oxyquinoline 5UTX5635HP
Antineoplastic Agents 0
CCL5 protein, human 0
Cisplatin Q20Q21Q62J

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Johnny Cheuk-On Tang (JC)

Jean-Marie Lehn Laboratory, Guangzhou Huashang College, Guangzhou, Guangdong 511300, P.R. China.

Dessy Chan (D)

State Key Laboratory of Chemical Biology and Drug Discovery, The Hong Kong Polytechnic University, Hong Kong, SAR 999077, P.R. China.

Po-Yee Chung (PY)

State Key Laboratory of Chemical Biology and Drug Discovery, The Hong Kong Polytechnic University, Hong Kong, SAR 999077, P.R. China.

Yijiang Liu (Y)

School of Biological Sciences, Nanyang Technological University, Singapore 639798, Republic of Singapore.

Alfred King-Yin Lam (AK)

Griffith Medical School, Griffith University, Gold Coast, QLD 4222, Australia.

Simon Law (S)

Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, SAR 999077, P.R. China.

Wolin Huang (W)

Jean-Marie Lehn Laboratory, Guangzhou Huashang College, Guangzhou, Guangdong 511300, P.R. China.

Albert Sun-Chi Chan (AS)

President Office, Guangzhou Huashang College, Guangzhou, Guangzhou 511300, P.R. China.

Kim-Hung Lam (KH)

State Key Laboratory of Chemical Biology and Drug Discovery, The Hong Kong Polytechnic University, Hong Kong, SAR 999077, P.R. China.

Yuanyuan Zhou (Y)

State Key Laboratory of Chemical Biology and Drug Discovery, The Hong Kong Polytechnic University, Hong Kong, SAR 999077, P.R. China.

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Classifications MeSH