Robotic kidney transplant has superior outcomes compared to open kidney transplant: results of a propensity match analysis.

Kidney transplantation Robot-assisted transplant Robotic kidney transplant Robotic surgery Robotic transplant

Journal

Surgical endoscopy
ISSN: 1432-2218
Titre abrégé: Surg Endosc
Pays: Germany
ID NLM: 8806653

Informations de publication

Date de publication:
05 Oct 2024
Historique:
received: 21 04 2024
accepted: 13 09 2024
medline: 6 10 2024
pubmed: 6 10 2024
entrez: 5 10 2024
Statut: aheadofprint

Résumé

Several studies have demonstrated the feasibility of robotic kidney transplant (RKT) as a safe alternative to open kidney transplant (OKT). However, significant selection bias in RKT patient selection limits meaningful comparison between the two techniques. This is a single-center retrospective review of a prospectively maintained kidney transplant database (2021-2024). Outcomes after the first 50 "non-selected" RKTs are compared with a contemporary cohort of 100 OKTs after propensity score matching for age, gender, BMI and type of donation (living vs deceased). Data pertinent to recipient demographics, intraoperative parameters, and short-term post-operative outcomes were collected and compared. Both groups were well-matched for recipient age, gender, BMI, and donation type. RKT group had significantly longer total operative time (RKT 258 min vs. OKT 183 min; p < 0.0001) and warm ischemia time (RKT 37 min vs. OKT 31 min; p < 0.0001) but significantly less blood loss (OKT 155 ml vs. RKT 93 ml). Average length of hospital stay for both groups was 5 days, with OKT group demonstrating significantly higher rates of post-operative complications (OKT 31% vs. RKT 14%; p = 0.028), return to OR (OKT 15% vs. RKT 2%; p = 0.021), hematoma (OKT 13% vs. RKT 2%; p = 0.0355), and lymphocele (OKT 25% vs. RKT 6%; p = 0.0039). OKT group also had higher 30-day readmission rate (OKT 31% vs. RKT 14%) and post-operative opioid requirement (OKT 93 MME vs. RKT 65; p = 0.0254). There were no differences in rates of wound infection, urine leaks, delayed graft function, acute rejection, graft loss, and patient death between the two groups. RKT is a safe and viable alternative to OKT as a first-choice procedure for all patients with ESRD. RKT offers many advantages over OKT which can lead to its wider adoption in the coming years as the new standard of care for ESRD patients.

Sections du résumé

BACKGROUND BACKGROUND
Several studies have demonstrated the feasibility of robotic kidney transplant (RKT) as a safe alternative to open kidney transplant (OKT). However, significant selection bias in RKT patient selection limits meaningful comparison between the two techniques.
METHODS METHODS
This is a single-center retrospective review of a prospectively maintained kidney transplant database (2021-2024). Outcomes after the first 50 "non-selected" RKTs are compared with a contemporary cohort of 100 OKTs after propensity score matching for age, gender, BMI and type of donation (living vs deceased). Data pertinent to recipient demographics, intraoperative parameters, and short-term post-operative outcomes were collected and compared.
RESULTS RESULTS
Both groups were well-matched for recipient age, gender, BMI, and donation type. RKT group had significantly longer total operative time (RKT 258 min vs. OKT 183 min; p < 0.0001) and warm ischemia time (RKT 37 min vs. OKT 31 min; p < 0.0001) but significantly less blood loss (OKT 155 ml vs. RKT 93 ml). Average length of hospital stay for both groups was 5 days, with OKT group demonstrating significantly higher rates of post-operative complications (OKT 31% vs. RKT 14%; p = 0.028), return to OR (OKT 15% vs. RKT 2%; p = 0.021), hematoma (OKT 13% vs. RKT 2%; p = 0.0355), and lymphocele (OKT 25% vs. RKT 6%; p = 0.0039). OKT group also had higher 30-day readmission rate (OKT 31% vs. RKT 14%) and post-operative opioid requirement (OKT 93 MME vs. RKT 65; p = 0.0254). There were no differences in rates of wound infection, urine leaks, delayed graft function, acute rejection, graft loss, and patient death between the two groups.
CONCLUSION CONCLUSIONS
RKT is a safe and viable alternative to OKT as a first-choice procedure for all patients with ESRD. RKT offers many advantages over OKT which can lead to its wider adoption in the coming years as the new standard of care for ESRD patients.

Identifiants

pubmed: 39368003
doi: 10.1007/s00464-024-11301-z
pii: 10.1007/s00464-024-11301-z
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Auteurs

Amen Z Kiani (AZ)

Section of Abdominal Transplant, Department of General Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA. amen@wustl.edu.

Angela L Hill (AL)

Section of Abdominal Transplant, Department of General Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.

Neeta Vachharajani (N)

Section of Abdominal Transplant, Department of General Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.

Jesse Davidson (J)

Section of Abdominal Transplant, Department of General Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.

Kristin Progar (K)

Department of Pharmacy, Barnes-Jewish Hospital, St. Louis, MO, 63110, USA.

Franklin Olumba (F)

Section of Abdominal Transplant, Department of General Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.

Jennifer Yu (J)

Section of Abdominal Transplant, Department of General Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.

Darren Cullinan (D)

Section of Abdominal Transplant, Department of General Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.

Gregory Martens (G)

Section of Abdominal Transplant, Department of General Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.

Yiing Lin (Y)

Section of Abdominal Transplant, Department of General Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.

William C Chapman (WC)

Section of Abdominal Transplant, Department of General Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.

Majella B Doyle (MB)

Section of Abdominal Transplant, Department of General Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.

Jason R Wellen (JR)

Section of Abdominal Transplant, Department of General Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.

Adeel S Khan (AS)

Section of Abdominal Transplant, Department of General Surgery, Washington University School of Medicine, St. Louis, MO, 63110, USA.

Classifications MeSH