tsCRISPR based identification of Rab proteins required for the recycling of
Drosophila photoreceptors
Rab proteins
TRPL ion channel
endoplasmic reticulum
endosomal trafficking
protein transport in polarized cells
recycling pathway
trans-Golgi
Journal
Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250
Informations de publication
Date de publication:
2024
2024
Historique:
received:
06
06
2024
accepted:
05
09
2024
medline:
7
10
2024
pubmed:
7
10
2024
entrez:
7
10
2024
Statut:
epublish
Résumé
In polarized cells, the precise regulation of protein transport to and from the plasma membrane is crucial to maintain cellular function. Dysregulation of intracellular protein transport in neurons can lead to neurodegenerative diseases such as Retinitis Pigmentosa, Alzheimer's and Parkinson's disease. Here we used the light-dependent transport of the TRPL (transient receptor potential-like) ion channel in
Identifiants
pubmed: 39372952
doi: 10.3389/fcell.2024.1444953
pii: 1444953
pmc: PMC11450138
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1444953Informations de copyright
Copyright © 2024 Zeger, Stanisławczyk, Bulić, Binder and Huber.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.