Invasive management of atrial tachycardias using a novel lattice-tip catheter combining high-density mapping and dual ablation properties: initial real-world experience.

Atrial tachycardia Electroanatomical mapping Focal pulsed field ablation High-density mapping

Journal

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing
ISSN: 1572-8595
Titre abrégé: J Interv Card Electrophysiol
Pays: Netherlands
ID NLM: 9708966

Informations de publication

Date de publication:
07 Oct 2024
Historique:
received: 03 08 2024
accepted: 27 09 2024
medline: 8 10 2024
pubmed: 8 10 2024
entrez: 7 10 2024
Statut: aheadofprint

Résumé

Invasive management of atrial tachycardias(ATs) requires proper diagnosis of the mechanism followed by elimination of the responsible substrate. A novel lattice-tip catheter with both high-density mapping and dual ablation properties(radiofrequency-RF/pulsed field ablation-PFA) has been recently introduced for catheter ablation of atrial fibrillation. We present the first study to assess its performance in the management of ATs (diagnostic and therapeutic). Patients with documented ATs were selected. Activation mapping was used for the establishment of the AT mechanism. Confirmation with entrainment was performed, whenever appropriate. Accuracy of the activation mapping in diagnosis, acute ablation efficacy, and procedural characteristics were the study endpoints. Twenty patients were included (12 cavotricuspid isthmus-dependent atrial flutters, 5 mitral flutters, 2 roof flutters, and 2 focal ATs). Proper diagnosis was established by activation mapping in all cases. The mean mapping time was 7.85 ± 3.06 min with 296.82 ± 150.9 mean mapping points/minute. The mean ablation time was 54.25 ± 42.97 s. Conversion to sinus rhythm during ablation was achieved in all cases with the exception of a roof flutter that converted to mitral flutter and a case of a parahisian AT in which ablation was not attempted. Patients that received ablation did not experience any arrhythmia recurrence in a mean follow up of 4.14 ± 0.91 months. No major or minor complications occurred. The lattice-tip catheter and its dedicated electroanatomical mapping system provided sufficiently detailed activation mapping for the diagnosis of the AT mechanism. The delivered lesions were highly effective acutely, with no adverse events. However, limitations exist and should be acknowledged.

Sections du résumé

BACKGROUND BACKGROUND
Invasive management of atrial tachycardias(ATs) requires proper diagnosis of the mechanism followed by elimination of the responsible substrate. A novel lattice-tip catheter with both high-density mapping and dual ablation properties(radiofrequency-RF/pulsed field ablation-PFA) has been recently introduced for catheter ablation of atrial fibrillation. We present the first study to assess its performance in the management of ATs (diagnostic and therapeutic).
METHODS METHODS
Patients with documented ATs were selected. Activation mapping was used for the establishment of the AT mechanism. Confirmation with entrainment was performed, whenever appropriate. Accuracy of the activation mapping in diagnosis, acute ablation efficacy, and procedural characteristics were the study endpoints.
RESULTS RESULTS
Twenty patients were included (12 cavotricuspid isthmus-dependent atrial flutters, 5 mitral flutters, 2 roof flutters, and 2 focal ATs). Proper diagnosis was established by activation mapping in all cases. The mean mapping time was 7.85 ± 3.06 min with 296.82 ± 150.9 mean mapping points/minute. The mean ablation time was 54.25 ± 42.97 s. Conversion to sinus rhythm during ablation was achieved in all cases with the exception of a roof flutter that converted to mitral flutter and a case of a parahisian AT in which ablation was not attempted. Patients that received ablation did not experience any arrhythmia recurrence in a mean follow up of 4.14 ± 0.91 months. No major or minor complications occurred.
CONCLUSION CONCLUSIONS
The lattice-tip catheter and its dedicated electroanatomical mapping system provided sufficiently detailed activation mapping for the diagnosis of the AT mechanism. The delivered lesions were highly effective acutely, with no adverse events. However, limitations exist and should be acknowledged.

Identifiants

pubmed: 39375296
doi: 10.1007/s10840-024-01928-2
pii: 10.1007/s10840-024-01928-2
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Références

Markowitz SM, Thomas G, Liu CF, et al. Atrial tachycardias and atypical atrial flutters: mechanisms and approaches to ablation. Arrhythm Electrophysiol Rev. 2019;8(2):131–7. https://doi.org/10.15420/aer.2019.17.2 .
doi: 10.15420/aer.2019.17.2 pubmed: 31114688 pmcid: 6528065
Reddy VY, Anter E, Rackauskas G, et al. Lattice-tip focal ablation catheter that toggles between radiofrequency and pulsed field energy to treat atrial fibrillation: a first-in-human trial. Circ Arrhythm Electrophysiol. 2020;13(6):e008718. https://doi.org/10.1161/CIRCEP.120.008718 .
doi: 10.1161/CIRCEP.120.008718 pubmed: 32383391
Reddy VY, Peichl P, Anter E, et al. A focal ablation catheter toggling between radiofrequency and pulsed field energy to treat atrial fibrillation. JACC Clin Electrophysiol. 2023;9(8 Pt 3):1786–801. https://doi.org/10.1016/j.jacep.2023.04.002 .
doi: 10.1016/j.jacep.2023.04.002 pubmed: 37227340
Tohoku S, Bordignon S, Schaack D, et al. Initial real-world data on catheter ablation in patients with persistent atrial fibrillation using the novel lattice-tip focal pulsed-field ablation catheter. Europace. 2024;26(6):euae129. https://doi.org/10.1093/europace/euae129 .
doi: 10.1093/europace/euae129 pubmed: 38916275 pmcid: 11197047
Reddy VY, Neužil P, Peichl P, et al. A lattice-tip temperature-controlled radiofrequency ablation catheter: durability of pulmonary vein isolation and linear lesion block. JACC Clin Electrophysiol. 2020;6(6):623–35. https://doi.org/10.1016/j.jacep.2020.01.002 .
doi: 10.1016/j.jacep.2020.01.002 pubmed: 32553211
Anter E, Mansour M, Nair DG, et al. Dual-energy lattice-tip ablation system for persistent atrial fibrillation: a randomized trial. Nat Med. 2024;30(8):2303–10. https://doi.org/10.1038/s41591-024-03022-6 .
doi: 10.1038/s41591-024-03022-6 pubmed: 38760584 pmcid: 11333282
Kapur S, Barbhaiya C, Deneke T, Michaud GF. Esophageal injury and atrioesophageal fistula caused by ablation for atrial fibrillation. Circulation. 2017;136(13):1247–55. https://doi.org/10.1161/CIRCULATIONAHA.117.025827 .
doi: 10.1161/CIRCULATIONAHA.117.025827 pubmed: 28947480
Baccillieri MS, Rizzo S, De Gaspari M, et al. Anatomy of the cavotricuspid isthmus for radiofrequency ablation in typical atrial flutter. Heart Rhythm. 2019;16(11):1611–8. https://doi.org/10.1016/j.hrthm.2019.05.030 .
doi: 10.1016/j.hrthm.2019.05.030 pubmed: 31150815
Wittkampf FH, van Oosterhout MF, Loh P, et al. Where to draw the mitral isthmus line in catheter ablation of atrial fibrillation: histological analysis. Eur Heart J. 2005;26(7):689–95. https://doi.org/10.1093/eurheartj/ehi095 .
doi: 10.1093/eurheartj/ehi095 pubmed: 15637084
Del Monte A, Della Rocca DG, Pannone L, et al. Coronary vasospasm during isthmus pulsed field ablation with wide area focal catheter. Circ Arrhythm Electrophysiol. 2024. https://doi.org/10.1161/CIRCEP.124.012923 .
Zhang C, Neuzil P, Petru J, et al. Coronary artery spasm during pulsed field vs radiofrequency catheter ablation of the mitral isthmus. JAMA Cardiol. 2024;9(1):72–7. https://doi.org/10.1001/jamacardio.2023.4405 .
doi: 10.1001/jamacardio.2023.4405 pubmed: 38019505
Miller JM, Tanawuttiwat T. Atrial tachycardias after ablation of atrial fibrillation: a better mousetrap? JACC Clin Electrophysiol. 2021;7(7):950–2. https://doi.org/10.1016/j.jacep.2021.06.008 .
doi: 10.1016/j.jacep.2021.06.008 pubmed: 34294392
Urbani A, Tohoku S, Bordignon S, et al. Durable LAA isolation combining pulsed field ablation and radiofrequency linear lesions in a patient with a therapy refractory left atrial appendage tachycardia. J Interv Card Electrophysiol. 2024. https://doi.org/10.1007/s10840-024-01862-3 .

Auteurs

Ourania Kariki (O)

Arrhythmia Unit, Onassis Cardiac Surgery Center, 17674, Athens, Greece.

Panagiotis Mililis (P)

Arrhythmia Unit, Onassis Cardiac Surgery Center, 17674, Athens, Greece.

Athanasios Saplaouras (A)

Arrhythmia Unit, Onassis Cardiac Surgery Center, 17674, Athens, Greece.

Theodoros Efremidis (T)

Arrhythmia Unit, Onassis Cardiac Surgery Center, 17674, Athens, Greece.

Stylianos Dragasis (S)

Arrhythmia Unit, Onassis Cardiac Surgery Center, 17674, Athens, Greece.

Konstantinos P Letsas (KP)

Arrhythmia Unit, Onassis Cardiac Surgery Center, 17674, Athens, Greece. k.letsas@gmail.com.

Michael Efremidis (M)

Arrhythmia Unit, Onassis Cardiac Surgery Center, 17674, Athens, Greece.

Classifications MeSH