Fermented Polyherbal Formulation Restored Ricinoleic Acid-Induced Diarrhea in Sprague Dawley Rats and Exhibited


Journal

Journal of pathogens
ISSN: 2090-3057
Titre abrégé: J Pathog
Pays: Egypt
ID NLM: 101571433

Informations de publication

Date de publication:
2024
Historique:
received: 05 03 2024
revised: 11 07 2024
accepted: 04 09 2024
medline: 8 10 2024
pubmed: 8 10 2024
entrez: 8 10 2024
Statut: epublish

Résumé

The involvement of multiple antibiotic-resistant gastrointestinal pathogens in diarrhea aggravates the disease condition uncontrollably. The current study aimed to find and develop a suitable formulation utilizing multiple natural components from known plant sources to augment the current therapeutic outcomes. The hydroethanolic extraction method was applied through boiling and fermentation on ancient observation-based efficacious plant parts for developing the antidiarrheal polyherbal formulation AP-01. An animal study model of diarrhea was used to evaluate the safety and efficacy of the formulation. The formulation was tested

Identifiants

pubmed: 39376598
doi: 10.1155/2024/1997064
pmc: PMC11458275
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1997064

Informations de copyright

Copyright © 2024 Subhanil Chakraborty et al.

Déclaration de conflit d'intérêts

The authors declare that they have no conflicts of interest.

Auteurs

Subhanil Chakraborty (S)

Omics Laboratory, Department of Biotechnology University of North Bengal, Raja Rammohunpur, P.O. NBU, Darjeeling, West Bengal 734013, India.

Babli Roy (B)

Department of Chemistry Tufanganj Mahavidyalaya, P.O. Tufanganj, New Town, Coochbehar, West Bengal 736160, India.

Subhajit Sen (S)

Omics Laboratory, Department of Biotechnology University of North Bengal, Raja Rammohunpur, P.O. NBU, Darjeeling, West Bengal 734013, India.
DBT-NECAB Assam Agricultural University, Jorhat, Assam 785013, India.

Santi M Mandal (SM)

Central Research Facility Indian Institute of Technology, Kharagpur, West Bengal 721302, India.

Arghya Das (A)

Department of Microbiology AIIMS, Madurai, Tamil Nadu 625002, India.

Ranadhir Chakraborty (R)

Omics Laboratory, Department of Biotechnology University of North Bengal, Raja Rammohunpur, P.O. NBU, Darjeeling, West Bengal 734013, India.

Classifications MeSH