α-Arbutin ameliorates UVA-induced photoaging through regulation of the SIRT3/PGC-1α pathway.

HaCaT mitochondrial biogenesis photoprotective sirtuin 3 skin

Journal

Frontiers in pharmacology
ISSN: 1663-9812
Titre abrégé: Front Pharmacol
Pays: Switzerland
ID NLM: 101548923

Informations de publication

Date de publication:
2024
Historique:
received: 07 04 2024
accepted: 11 09 2024
medline: 8 10 2024
pubmed: 8 10 2024
entrez: 8 10 2024
Statut: epublish

Résumé

Owing to its tyrosinase inhibitory activity, α-arbutin has been added to several skin care products as a skin-lightening agent. However, the protective effect of α-arbutin against ultraviolet A (UVA)-induced photoaging has not been well investigated. The present study was designed to investigate the photoprotective effect and mechanism of α-arbutin against UVA-induced photoaging. In vitro experiments, HaCaT cells were treated with UVA at a dose of 3 J/cm

Identifiants

DOI: 10.3389/fphar.2024.1413530 PMID: 39376600 PMC: PMC11456475
pubmed: 39376600
doi: 10.3389/fphar.2024.1413530
pii: 1413530
pmc: PMC11456475
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1413530

Informations de copyright

Copyright © 2024 Lu, Zhou, Liang, Liang, Yu, Li, Zhang, Lu, Zheng, Hao, Shu and Liu.

Déclaration de conflit d'intérêts

Authors QZ and PS were employed by Shenzhen Hujia Technology Co., Ltd. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Auteurs

Fang Lu (F)

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.

Qi Zhou (Q)

HBN Research Institute and Biological Laboratory, Shenzhen Hujia Technology Co., Ltd., Shenzhen, Guangdong, China.

Mengdi Liang (M)

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.

Huicong Liang (H)

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.

Yiwei Yu (Y)

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.

Yang Li (Y)

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.

Yan Zhang (Y)

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.

Ling Lu (L)

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.

Yan Zheng (Y)

Department of Dermatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

Jiejie Hao (J)

Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.

Peng Shu (P)

HBN Research Institute and Biological Laboratory, Shenzhen Hujia Technology Co., Ltd., Shenzhen, Guangdong, China.
State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, Xinjiang, China.
University of Chinese Academy of Sciences, Beijing, China.

Jiankang Liu (J)

Department of Dermatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
School of Health and Life Sciences, University of Health and Rehabilitation Sciences, Qingdao, Shandong, China.

Classifications MeSH