The use of transvaginal ultrasound alters physiologic uterine peristalsis in gynecologic participants.

To study whether transvaginal ultrasound (TVUS) affected the uterine peristalsis (UP) patterns in nonpregnant participants. Institutional review board-approved, prospective observational cohort study. The noninvasive UP imaging (UPI) system uses electrode patches placed on the patient's skin just above the pubic bone and on the low back to quantify the 3-dimensional electrical activation pattern during UP by calculating peristalsis frequency, duration, magnitude, and activation ratio. A 20-minute UPI scan was completed without TVUS followed by a 10-minute UPI scan acquired simultaneously during TVUS examination as a comparison. University medical center. Twenty-eight participants with regular menstrual cycles not taking hormonal medication and with a normal uterus were included in analysis. Subjects were imaged longitudinally during the four phases of the menstrual cycle (menses, proliferative, periovulatory, and secretory) with a UPI scan followed by concurrent TVUS and UPI scan. Serum hormone levels (estradiol and progesterone) and TVUS evaluating follicular development were obtained during each visit to confirm menstrual cycle phase. Duration, frequency, magnitude, and activation ratio of the UP waves. With the use of simultaneous TVUS, UP waves had a change in at least one of the outcomes measured in all visits. The frequency, magnitude, and duration were significantly higher with TVUS use in all phases of the menstrual cycle. The activation ratio was higher with TVUS during all phases except the periovulatory phase. This study demonstrated that TVUS may inherently affect UP waves. Therefore, noninvasive technology may more accurately measure physiologic peristalsis waves.

Informations de copyright

© 2024 The Authors.

Déclaration de conflit d'intérêts

K.A. reports funding from March of Dimes Center Grant (22-FY14-486). S.W. has nothing to disclose. S.P. has nothing to disclose. Q.W. has nothing to disclose. Y.W. is a scientific consultant for Medtronic and EP Solution and reports grant R01HD104822 (PIs Wang/Schwartz/Cahill) and grants from the National Institutes of Health/National Institute of Child Health and Human Development (R01HD094381, PIs Wang/Cahill), Burroughs Wellcome Fund Preterm Birth Initiative (NGP10119, PI Wang), Bill & Melinda Gates Foundation (INV-037302, INV-005417, INV-035476, and 16INV-037302, PI Wang), and Institute of Clinical and Translational Science (5927, PI Wang) for the submitted work. V.R. Bill and Melinda Gates Foundation (INV-037302).