Macrophages enhance sodium channel expression in cardiomyocytes.

AV-conduction AV-node Connexins Cx43 Macrophages Nav1.5 Sodium channel

Journal

Basic research in cardiology
ISSN: 1435-1803
Titre abrégé: Basic Res Cardiol
Pays: Germany
ID NLM: 0360342

Informations de publication

Date de publication:
09 Oct 2024
Historique:
received: 18 12 2023
accepted: 29 09 2024
revised: 22 09 2024
medline: 9 10 2024
pubmed: 9 10 2024
entrez: 9 10 2024
Statut: aheadofprint

Résumé

Cardiac macrophages facilitate electrical conduction through the atrioventricular-node (AV) in mice. A possible role for cardiomyocyte-macrophage coupling on the effect of antiarrhythmic therapy has not been investigated yet. Holter monitoring was conducted in LysM

Identifiants

pubmed: 39382673
doi: 10.1007/s00395-024-01084-8
pii: 10.1007/s00395-024-01084-8
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s).

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Auteurs

N V Bogert (NV)

Department of Cardiology, University Hospital Heidelberg, Ruprecht-Karls-University Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg, Mannheim, Germany.

M Therre (M)

Department of Cardiology, University Hospital Heidelberg, Ruprecht-Karls-University Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg, Mannheim, Germany.

S Din (S)

Department of Cardiology, University Hospital Heidelberg, Ruprecht-Karls-University Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg, Mannheim, Germany.

J Furkel (J)

Department of Cardiology, University Hospital Heidelberg, Ruprecht-Karls-University Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg, Mannheim, Germany.

X Zhou (X)

Department of Cardiology, University Medical Centre Mannheim, Ruprecht-Karls-University Heidelberg, Mannheim, Germany.
German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg, Mannheim, Germany.

I El-Battrawy (I)

Department of Cardiology, BG Universitätsklinikum Bergmannsheil Bochum, Ruhr-University, Bochum, Germany.
Institut Für Forschung Und Lehre (IFL), Molecular and Experimental Cardiology, Ruhr University Bochum, Bochum, Germany.
German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg, Mannheim, Germany.

J Heineke (J)

Department of Cardiovascular Physiology, European Center for Angioscience, Medical Faculty Mannheim, Ruprecht-Karls-University Heidelberg, Mannheim, Germany.
German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg, Mannheim, Germany.

P A Schweizer (PA)

Department of Cardiology, University Hospital Heidelberg, Ruprecht-Karls-University Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg, Mannheim, Germany.

I Akin (I)

Department of Cardiology, University Medical Centre Mannheim, Ruprecht-Karls-University Heidelberg, Mannheim, Germany.
German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg, Mannheim, Germany.

H A Katus (HA)

Department of Cardiology, University Hospital Heidelberg, Ruprecht-Karls-University Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg, Mannheim, Germany.

N Frey (N)

Department of Cardiology, University Hospital Heidelberg, Ruprecht-Karls-University Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg, Mannheim, Germany.

F Leuschner (F)

Department of Cardiology, University Hospital Heidelberg, Ruprecht-Karls-University Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg, Mannheim, Germany.

M H Konstandin (MH)

Department of Cardiology, University Hospital Heidelberg, Ruprecht-Karls-University Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany. mathias.konstandin@med.uni-heidelberg.de.
German Centre for Cardiovascular Research (DZHK), Partner Site Heidelberg, Mannheim, Germany. mathias.konstandin@med.uni-heidelberg.de.

Classifications MeSH