Design, construction, and use of a tapered-spiral, quadrature

MRI X‐nuclei chick embryo double‐tuned coil dual‐tuned coil in ovo sodium

Journal

Medical physics
ISSN: 2473-4209
Titre abrégé: Med Phys
Pays: United States
ID NLM: 0425746

Informations de publication

Date de publication:
09 Oct 2024
Historique:
revised: 30 08 2024
received: 27 06 2024
accepted: 18 09 2024
medline: 9 10 2024
pubmed: 9 10 2024
entrez: 9 10 2024
Statut: aheadofprint

Résumé

In ovo MR presents a promising and viable alternative to traditional in vivo small animal experiments. Sodium MRI complements proton MRI by providing potential access to tissue cellular metabolism. Despite its abundance, sodium MRI is challenged by lower MR sensitivity and faster relaxation times compared to proton MRI. Ensuring a high signal-to-noise ratio and effective B This study introduces a novel, highly optimized, double-tuned coil design, specifically for MR scans of chick embryos. A tapered-spiral, double-tuned coil was designed and constructed following careful consideration of design parameters. The performance of the coil was rigorously assessed through bench tests, and final validation was conducted on a 7 T MRI scanner using a chick embryo. Bench tests demonstrated that the return losses for both The innovative design of the proposed double-tuned coil, characterized by its unique arrangement, offers improved performance. This design has the potential to significantly enhance the quality of in ovo

Sections du résumé

BACKGROUND BACKGROUND
In ovo MR presents a promising and viable alternative to traditional in vivo small animal experiments. Sodium MRI complements proton MRI by providing potential access to tissue cellular metabolism. Despite its abundance, sodium MRI is challenged by lower MR sensitivity and faster relaxation times compared to proton MRI. Ensuring a high signal-to-noise ratio and effective B
PURPOSE OBJECTIVE
This study introduces a novel, highly optimized, double-tuned coil design, specifically for MR scans of chick embryos.
METHODS METHODS
A tapered-spiral, double-tuned coil was designed and constructed following careful consideration of design parameters. The performance of the coil was rigorously assessed through bench tests, and final validation was conducted on a 7 T MRI scanner using a chick embryo.
RESULTS RESULTS
Bench tests demonstrated that the return losses for both
CONCLUSIONS CONCLUSIONS
The innovative design of the proposed double-tuned coil, characterized by its unique arrangement, offers improved performance. This design has the potential to significantly enhance the quality of in ovo

Identifiants

pubmed: 39382836
doi: 10.1002/mp.17448
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024 The Author(s). Medical Physics published by Wiley Periodicals LLC on behalf of American Association of Physicists in Medicine.

Références

Hu R, Kleimaier D, Malzacher M, Hoesl MAU, Paschke NK, Schad LR. X‐nuclei imaging: current state, technical challenges, and future directions. J Magn Reson Imaging. 2020;51(2):355‐376. doi:10.1002/jmri.26780
Worthoff WA, Shymanskaya A, Choi CH, Felder J, Oros‐Peusquens AM, Shah NJ. Multinuclear MR imaging and spectroscopy. Quantitative MRI of the Brain. 2nd ed. CRC Press; 2018.
Shah NJ, Worthoff WA, Langen KJ. Imaging of sodium in the brain: a brief review. NMR Biomed. 2016;29(2):162‐174. doi:10.1002/nbm.3389
Thulborn K, Lui E, Guntin J, et al. Quantitative sodium MRI of the human brain at 9.4 T provides assessment of tissue sodium concentration and cell volume fraction during normal aging. NMR Biomed. 2016;29(2):137‐143. doi:10.1002/nbm.3312
Thulborn KR, Davis D, Adams H, Gindin T, Zhou J>. Quantitative tissue sodium concentration mapping of the growth of focal cerebral tumors with sodium magnetic resonance imaging. Magn Reson Med. 1999;41(2):351‐359. doi:10.1002/(SICI)1522‐2594(199902)41:2<351::AID‐MRM20>3.0.CO;2‐H
Ouwerkerk R, Bleich KB, Gillen JS, Pomper MG, Bottomley PA. Tissue sodium concentration in human brain tumors as measured with 23Na MR imaging. Radiology. 2003;227(2):529‐537. doi:10.1148/radiol.2272020483
Inglese M, Madelin G, Oesingmann N, et al. Brain tissue sodium concentration in multiple sclerosis: a sodium imaging study at 3 tesla. Brain. 2010;133(3):847‐857. doi:10.1093/brain/awp334
Konstandin S, Nagel AM. Measurement techniques for magnetic resonance imaging of fast relaxing nuclei. Magn Reson Mater Phy. 2014;27(1):5‐19. doi:10.1007/s10334‐013‐0394‐3
Choi CH, Hong SM, Felder J, Shah NJ. The state‐of‐the‐art and emerging design approaches of double‐tuned RF coils for X‐nuclei, brain MR imaging and spectroscopy: a review. Magn Reson Imaging. 2020;72:103‐116. doi:10.1016/j.mri.2020.07.003
Matson GB, Vermathen P, Hill TC. A practical double‐tuned 1H/31P quadrature birdcage headcoil optimized for 31P operation. Magn Reson Med. 1999;42(1):173‐182. doi:10.1002/(sici)1522‐2594(199907)42:1<173::aid‐mrm23>3.0.co;2‐o
Fitzsimmons JR, Beck BL, Ralph Brooker H. Double resonant quadrature birdcage. Magn Reson Med. 1993;30(1):107‐114. doi:10.1002/mrm.1910300116
Alsop DC, Connick TJ, Mizsei G. A spiral volume coil for improved RF field homogeneity at high static magnetic field strength. Magn Reson Med. 1998;40(1):49‐54. doi:10.1002/mrm.1910400107
Tomanek B, Volotovskyy V, Gruwel MLH, McKenzie E, King SB. Double‐frequency birdcage volume coils for 4.7T and 7T. Concepts Magn Reson B: Magn Reson Eng. 2005;26B(1):16‐22. doi:10.1002/cmr.b.20038
Murphyboesch J, Srinivasan R, Carvajal L, Brown TR. Two configurations of the four‐ring birdcage coil for 1H imaging and 1H‐decoupled 31P spectroscopy of the human head. J Magn Reson, Series B. 1994;103(2):103‐114. doi:10.1006/jmrb.1994.1017
Rath AR. Design and performance of a double‐tuned bird‐cage coil. J Magn Reson (1969). 1990;86(3):488‐495. doi:10.1016/0022‐2364(90)90026‐6
Hancu I, Boada FE, Shen GX. Three‐dimensional triple‐quantum‐filtered23Na imaging of in vivo human brain. Magn Reson Med. 1999;42(6):1146‐1154. doi:10.1002/(SICI)1522‐2594(199912)42:6<1146::AID‐MRM20>3.0.CO;2‐S
Lim H, Thind K, Martinez‐Santiesteban FM, Scholl TJ. Construction and evaluation of a switch‐tuned (13) C—(1) H birdcage radiofrequency coil for imaging the metabolism of hyperpolarized (13) C‐enriched compounds. J Magn Reson Imaging. 2014;40(5):1082‐1090. doi:10.1002/jmri.24458
Dabirzadeh A, McDougall MP. Trap design for insertable second‐nuclei radiofrequency coils for magnetic resonance imaging and spectroscopy. Concepts Magn Reson B: Magn Reson Eng. 2009;35B(3):121‐132. doi:10.1002/cmr.b.20139
Ha Y, Choi CH, Worthoff WA, et al. Design and use of a folded four‐ring double‐tuned birdcage coil for rat brain sodium imaging at 9.4 T. J Magn Reson. 2018;286:110‐114. doi:10.1016/j.jmr.2017.12.003
Wiggins GC, Brown R, Lakshmanan K. High‐performance radiofrequency coils for 23Na MRI: brain and musculoskeletal applications. NMR Biomed. 2016;29(2):96‐106. doi:10.1002/nbm.3379
Shajan G, Mirkes C, Buckenmaier K, Hoffmann J, Pohmann R, Scheffler K. Three‐layered radio frequency coil arrangement for sodium MRI of the human brain at 9.4 Tesla. Magn Reson Med. 2016;75(2):906‐916. doi:10.1002/mrm.25666
Hong SM, Choi CH, Shah NJ, Felder J. Design of a folded, double‐tuned loop coil for 1H/X‐nuclei MRI applications. IEEE Trans Med Imaging. 2023;42(5):1424‐1430. doi:10.1109/TMI.2022.3228305
Meyerspeer M, Serés Roig E, Gruetter R, Magill AW. An improved trap design for decoupling multinuclear RF coils. Magn Reson Med. 2014;72(2):584‐590. doi:10.1002/mrm.24931
Ha Y, Choi CH, Shah NJ. Development and implementation of a PIN‐diode controlled, quadrature‐enhanced, double‐tuned RF coil for sodium MRI. IEEE Trans Med Imaging. 2018;37(7):1626‐1631. doi:10.1109/TMI.2017.2786466
Choi CH, Hong SM, Ha Y, Shah NJ. Design and construction of a novel 1H/19F double‐tuned coil system using PIN‐diode switches at 9.4T. J Magn Reson. 2017;279:11‐15. doi:10.1016/j.jmr.2017.04.005
Brown R, Lakshmanan K, Madelin G, et al. A flexible nested sodium and proton coil array with wideband matching for knee cartilage MRI at 3T. Magn Reson Med. 2016;76(4):1325‐1334. doi:10.1002/mrm.26017
Herrmann A, Taylor A, Murray P, Poptani H, Sée V. Magnetic resonance imaging for characterization of a chick embryo model of cancer cell metastases. Mol Imaging. 2018;17:1536012118809585. doi:10.1177/1536012118809585
Miebach L, Berner J, Bekeschus S. In ovo model in cancer research and tumor immunology. Front Immunol. 2022;13:1006064. doi:10.3389/fimmu.2022.1006064
Choi CH, Bruch M, Hong SM, et al. A modified quadrature birdcage coil incorporated with a curved feature for in ovo MRI at 7 T. IEEE OJEMB. 2024;5:534‐541. doi:10.1109/OJEMB.2024.3420231
Fantasia M, Galante A, Maggiorelli F, et al. Numerical and workbench design of 2.35 T double‐tuned (1H/23Na) nested RF birdcage coils suitable for animal size MRI. IEEE Trans Med Imaging. 2020;39(10):3175‐3186. doi:10.1109/TMI.2020.2988599
Zhang B, Lowrance D, Sarma MK, et al. 3T 31P/1H calf muscle coil for 1H and 31P MRI/MRS integrated with NIRS data acquisition. Magn Reson Med. 2024;91(6):2638‐2651. doi:10.1002/mrm.30025
Pak JS, Kim J, Lee JO, et al. A new 3.0T hybrid‐spiral‐birdcage (HSB) coil for improved homogeneity along Z‐axis. Proc Intl Soc Mag Reson Med. 2000:1393.
Yushkevich PA, Piven J, Hazlett HC, et al. User‐guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliability. Neuroimage. 2006;31(3):1116‐1128. doi:10.1016/j.neuroimage.2006.01.015
Gabrielli MG, Accili D. The chick chorioallantoic membrane: a model of molecular, structural, and functional adaptation to transepithelial ion transport and barrier function during embryonic development. J Biomed Biotechnol. 2010;2010:940741.
Kundeková B, Máčajová M, Meta M, Čavarga I, Bilčík B. Chorioallantoic membrane models of various avian species: differences and applications. Biology. 2021;10(4):301.
Choi CH, Ha Y, Veeraiah P, Felder J, Möllenhoff K, Shah NJ. Design and implementation of a simple multinuclear MRI system for ultra high‐field imaging of animals. J Magn Reson. 2016;273:28‐32. doi:10.1016/j.jmr.2016.10.007
Felder J, Celik AA, Choi CH, Schwan S, Shah NJ. 9.4 T small animal MRI using clinical components for direct translational studies. J Transl Med. 2017;15(1):264. doi:10.1186/s12967‐017‐1373‐7
Fiege DP, Romanzetti S, Mirkes CC, Brenner D, Shah NJ. Simultaneous single‐quantum and triple‐quantum‐filtered MRI of 23Na (SISTINA). Magn Reson Med. 2013;69(6):1691‐1696. doi:10.1002/mrm.24417
Worthoff WA, Shymanskaya A, Shah NJ. Relaxometry and quantification in simultaneously acquired single and triple quantum filtered sodium MRI. Magn Reson Med. 2019;81(1):303‐315. doi:10.1002/mrm.27387
Worthoff WA, Shymanskaya A, Lindemeyer J, Langen KJ, Shah NJ. Relaxometry and quantification in sodium MRI of cerebral gliomas: a FET‐PET and MRI small‐scale study. NMR Biomed. 2020;33(10):e4361. doi:10.1002/nbm.4361
Choi CH, Stegmayr C, Shymanskaya A, et al. An in vivo multimodal feasibility study in a rat brain tumour model using flexible multinuclear MR and PET systems. EJNMMI Phys. 2020;7(1):50. doi:10.1186/s40658‐020‐00319‐6
Shah NJ. Multimodal neuroimaging in humans at 9.4 T: a technological breakthrough towards an advanced metabolic imaging scanner. Brain Struct Funct. 2015;220(4):1867‐1884. doi:10.1007/s00429‐014‐0843‐4

Auteurs

Chang-Hoon Choi (CH)

Institute of Neuroscience and Medicine - 4, Forschungszentrum Jülich, Juelich, Germany.
Aachen University of Applied Sciences, Jülich, Germany.

Suk-Min Hong (SM)

Institute of Neuroscience and Medicine - 4, Forschungszentrum Jülich, Juelich, Germany.

Jörg Felder (J)

Institute of Neuroscience and Medicine - 4, Forschungszentrum Jülich, Juelich, Germany.
RWTH University, Aachen, Germany.

Maximilian Bruch (M)

Institute of Neuroscience and Medicine - 4, Forschungszentrum Jülich, Juelich, Germany.
Aachen University of Applied Sciences, Jülich, Germany.

Wieland A Worthoff (WA)

Institute of Neuroscience and Medicine - 4, Forschungszentrum Jülich, Juelich, Germany.

Sandra Krause (S)

Institute of Neuroscience and Medicine - 4, Forschungszentrum Jülich, Juelich, Germany.

N Jon Shah (NJ)

Institute of Neuroscience and Medicine - 4, Forschungszentrum Jülich, Juelich, Germany.
Institute of Neuroscience and Medicine - 11, Forschungszentrum Jülich, Juelich, Germany.
JARA - BRAIN - Translational Medicine, Aachen, Germany.
Department of Neurology, RWTH Aachen University, Aachen, Germany.

Classifications MeSH