Further validation of the association between

APOE gene Alzheimer’s disease MAPT gene MAPT haplotypes MAPT polymorphisms biomarkers cerebrospinal fluid dementia

Journal

Frontiers in molecular neuroscience
ISSN: 1662-5099
Titre abrégé: Front Mol Neurosci
Pays: Switzerland
ID NLM: 101477914

Informations de publication

Date de publication:
2024
Historique:
received: 01 07 2024
accepted: 28 08 2024
medline: 10 10 2024
pubmed: 10 10 2024
entrez: 10 10 2024
Statut: epublish

Résumé

Genetic studies have shown that variants in the microtubule-associated protein tau ( The study included 964 individuals: 113 with AD, 53 with mild cognitive impairment (MCI), 54 with other dementias, and 744 healthy controls. The results showed that individuals carrying the A allele in the In conclusion, further genetic studies are needed to elucidate the role of

Identifiants

DOI: 10.3389/fnmol.2024.1456670 PMID: 39386049 PMC: PMC11461444
pubmed: 39386049
doi: 10.3389/fnmol.2024.1456670
pmc: PMC11461444
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1456670

Informations de copyright

Copyright © 2024 Babić Leko, Španić Popovački, Willumsen, Nikolac Perković, Pleić, Zubčić, Langer Horvat, Vogrinc, Boban, Borovečki, Zemunik, de Silva and Šimić.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Auteurs

Mirjana Babić Leko (M)

Department for Neuroscience, Croatian Institute for Brain Research, University of Zagreb Medical School, Zagreb, Croatia.

Ena Španić Popovački (E)

Department for Neuroscience, Croatian Institute for Brain Research, University of Zagreb Medical School, Zagreb, Croatia.

Nanet Willumsen (N)

Reta Lila Weston Institute, Department of Clinical and Movement Neuroscience, UCL Queen Square Institute of Neurology, London, United Kingdom.

Matea Nikolac Perković (M)

Division of Molecular Medicine, Ruđer Bošković Institute, Zagreb, Croatia.

Nikolina Pleić (N)

Department of Biology and Human Genetics, School of Medicine, University of Split, Split, Croatia.

Klara Zubčić (K)

Department of Molecular Diagnostics and Genetics, Dubrava University Hospital, Zagreb, Croatia.

Lea Langer Horvat (L)

Department for Neuroscience, Croatian Institute for Brain Research, University of Zagreb Medical School, Zagreb, Croatia.

Željka Vogrinc (Ž)

Laboratory for Neurobiochemistry, Department of Laboratory Diagnostics, University Hospital Centre Zagreb, Zagreb, Croatia.

Marina Boban (M)

Department of Neurology, University Hospital Centre Zagreb, Kišpatićeva, Zagreb, Croatia.
School of Medicine, University of Zagreb, Zagreb, Croatia.

Fran Borovečki (F)

Department of Neurology, University Hospital Centre Zagreb, Kišpatićeva, Zagreb, Croatia.
School of Medicine, University of Zagreb, Zagreb, Croatia.
Department for Functional Genomics, Centre for Translational and Clinical Research, University of Zagreb Medical School, Zagreb, Croatia.

Tatijana Zemunik (T)

Department of Biology and Human Genetics, School of Medicine, University of Split, Split, Croatia.
Department of Nuclear Medicine, University Hospital Split, Split, Croatia.

Rohan de Silva (R)

Reta Lila Weston Institute, Department of Clinical and Movement Neuroscience, UCL Queen Square Institute of Neurology, London, United Kingdom.

Goran Šimić (G)

Department for Neuroscience, Croatian Institute for Brain Research, University of Zagreb Medical School, Zagreb, Croatia.

Classifications MeSH