Intranasal vs. intramuscular administration of azaperone, midazolam and ketamine in pigs.

To compare the efficacy of intranasal (IN) and intramuscular (IM) administrations of azaperone (3 mg kg In phase I, these animals were randomly assigned to intranasal (GIN, Latency to recumbency and duration of CR in GIN were shorter. CR scores did not vary between groups. Muscle relaxation was more intense in GIN at Trec. An initial tachycardia was observed, followed by a reduction in heart rate from T5 to T90 in both treatments ( IN administration was as effective as IM administration in promoting safe chemical restraint, with minimal changes in homeostasis, with a shorter duration and latency period.

Informations de copyright

Copyright © 2024 Rabelo, Gujanwski, Viana, de Paula, Rein, Rabelo and Valadäo.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.