Prevalence of carotid ultrasound screening in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study.
carotid ultrasound
childhood cancer
radiotherapy
survivorship
Journal
Cancer
ISSN: 1097-0142
Titre abrégé: Cancer
Pays: United States
ID NLM: 0374236
Informations de publication
Date de publication:
10 Oct 2024
10 Oct 2024
Historique:
revised:
18
08
2024
received:
29
11
2023
accepted:
06
09
2024
medline:
10
10
2024
pubmed:
10
10
2024
entrez:
10
10
2024
Statut:
aheadofprint
Résumé
Many childhood cancer survivors are at risk for cardiovascular disease and stroke. The North American Children's Oncology Group long-term follow-up guidelines recommend carotid ultrasound in cancer survivors 10 years after neck radiation therapy (RT) ≥40 Gy. The use of carotid ultrasound in this population has not been described. Survivors of childhood cancer diagnosed 1970-1999 (N = 8693) and siblings (N = 1989) enrolled in the Childhood Cancer Survivor Study were asked if they had ever had a carotid ultrasound. Prevalence of carotid ultrasound was evaluated. Prevalence ratios (PR) and 95% confidence intervals (CIs) were evaluated in multivariate Poisson regression models. Among participants with no reported cardiovascular condition, prevalence of carotid ultrasound among survivors with RT ≥40 Gy to the neck (N = 172) was 29.7% (95% CI, 22.5-36.8), significantly higher than those with <40 Gy (prevalence 10.7%; 95% CI, 9.9%-11.4%). Siblings without a cardiovascular condition (N = 1621) had the lowest prevalence of carotid ultrasound (4.7%; 95% CI, 3.6%-5.7%). In a multivariable models among survivors with no reported cardiovascular condition and RT ≥40 Gy to the neck, those who were over age 50 (vs. 18-49) at follow-up (PR = 1.82; 95% CI, 1.09-3.05), with a history of seeing a cancer specialist in the last 2 years (PR = 2.58; 95% CI, 1.53-4.33), or having a colonoscopy (PR = 2.02; 95% CI, 1.17-3.48) or echocardiogram (PR = 6.42; 95% CI, 1.54-26.85) were more likely to have had a carotid ultrasound. Many survivors do not undergo carotid ultrasound despite meeting existing guidelines. Health care delivery features such as having seen a cancer specialist or having other testing are relevant.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Childhood Cancer Survivor Study
ID : U24 CA55727
Organisme : Vickers
ID : P30 CA 008748
Informations de copyright
© 2024 American Cancer Society.
Références
Cancer Treatment & Survivorship Facts & Figures 2019‐2021. American Cancer Society. Atlanta, GA; 2019. Accessed June 10, 2023. https://www.cancer.org/content/dam/cancer‐org/research/cancer‐facts‐and‐statistics/cancer‐treatment‐and‐survivorship‐facts‐and‐figures/cancer‐treatment‐and‐survivorship‐facts‐and‐figures‐2019‐2021.pdf
Bowers DC, McNeil DE, Liu Y, et al. Stroke as a late treatment effect of Hodgkin's Disease: a report from the Childhood Cancer Survivor Study. J Clin Oncol. 2005;23(27):6508‐6515. doi:10.1200/jco.2005.15.107
Fullerton HJ, Stratton K, Mueller S, et al. Recurrent stroke in childhood cancer survivors. Neurology. 2015;85(12):1056‐1064. doi:10.1212/wnl.0000000000001951
Bowers DC, Liu Y, Leisenring W, et al. Late‐occurring stroke among long‐term survivors of childhood leukemia and brain tumors: a report from the Childhood Cancer Survivor Study. J Clin Oncol. 2006;24(33):5277‐5282. doi:10.1200/jco.2006.07.2884
Mueller S, Sear K, Hills NK, et al. Risk of first and recurrent stroke in childhood cancer survivors treated with cranial and cervical radiation therapy. Int J Radiat Oncol Biol Phys. 2013;86(4):643‐648. doi:10.1016/j.ijrobp.2013.03.004
Zamorano JL, Lancellotti P, Rodriguez Munoz D, et al. 2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines: the task force for cancer treatments and cardiovascular toxicity of the European Society of Cardiology (ESC). Eur Heart J. 2016;37(36):2768‐2801. doi:10.1093/eurheartj/ehw211
Group; CsO: Long‐Term Follow‐Up Guidelines for Survivors of Childhood, Adolescent, and Young Adult Cancers, Version 5.0, 2018. Accessed June 10, 2023. http://www.survivorshipguidelines.org/pdf/2018/cog_ltfu_guidelines_v5.pdf
Jonas DE, Feltner C, Amick HR, et al. Screening for asymptomatic carotid artery stenosis: a systematic review and meta‐analysis for the U.S. Preventive Services Task Force. Ann Intern Med. 2014;161(5):336‐346. doi:10.7326/m14‐0530
Abbott AL. Medical (nonsurgical) intervention alone is now best for prevention of stroke associated with asymptomatic severe carotid stenosis: results of a systematic review and analysis. Stroke. 2009;40(10):e573‐e583. doi:10.1161/strokeaha.109.556068
Brett AS, Levine JD. The case against identifying carotid stenosis in asymptomatic patients. JAMA Intern Med. 2014;174(12):2004‐2008. doi:10.1001/jamainternmed.2014.4920
Guirguis‐Blake JM, Webber EM, Coppola EL. Screening for asymptomatic carotid artery stenosis in the general population: an evidence update for the U.S. Preventive Services Task Force. Evidence Synthesis No. 199. AHRQ Publication No. 20‐05268‐EF‐1. Agency for Healthcare Research and Quality; 2021; Rockville, MD.
Robison LL, Armstrong GT, Boice JD, et al. The childhood cancer survivor study: a National Cancer Institute‐supported resource for outcome and intervention research. J Clin Oncol. 2009;27(14):2308‐2318. doi:10.1200/JCO.2009.22.3339
Zou G. A modified poisson regression approach to prospective studies with binary data. Am J Epidemiol. 2004;159(7):702‐706. doi:10.1093/aje/kwh090
Portet S. A primer on model selection using the Akaike Information Criterion. Infect Dis Model. 2020;5:111‐128. doi:10.1016/j.idm.2019.12.010
Yan AP, Chen Y, Henderson TO, et al. Adherence to surveillance for second malignant neoplasms and cardiac dysfunction in childhood cancer survivors: a Childhood Cancer Survivor Study. J Clin Oncol. 2020 May 20;38(15):1711‐1722. doi:10.1200/JCO.19.01825
Cox AJ, Hsu FC, Agarwal S, et al. Prediction of mortality using a multi‐bed vascular calcification score in the Diabetes Heart Study. Cardiovasc Diabetol. 2014;13(1):160. doi:10.1186/s12933‐014‐0160‐5
Ricotta JJ, Aburahma A, Ascher E, et al. Updated Society for Vascular Surgery guidelines for management of extracranial carotid disease. J Vasc Surg. 2011;54(3):e1‐e31. doi:10.1016/j.jvs.2011.07.031
Brott TG, Halperin JL, Abbara S, et al., 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline on the management of patients with extracranial carotid and vertebral artery disease. Stroke. 2011;42(8):e464‐e540. doi:10.1161/cir.0b013e31820d8c98
Armenian SH, Armstrong GT, Aune G, et al. Cardiovascular disease in survivors of childhood cancer: insights into epidemiology, pathophysiology, and prevention. J Clin Oncol. 2018;36(21):2135‐2144. doi:10.1200/JCO.2017.76.3920
Gibson TM, Li Z, Green DM, et al. Blood pressure status in adult survivors of childhood cancer: a report from the St. Jude Lifetime Cohort Study. Cancer Epidemiol Biomarkers Prev. 2017;26(12):1705‐1713. doi:10.1158/1055‐9965.epi‐17‐0510
Khanna A, Pequeno P, Gupta S, et al. Increased risk of all cardiovascular disease subtypes among childhood cancer survivors: population‐based matched cohort study. Circulation. 2019 Sep 17;140(12):1041‐1043. doi:10.1161/circulationaha.119.041403
Horst KC, Fero KE, Hancock SL, et al. Breast imaging in women previously irradiated for Hodgkin lymphoma. Am J Clin Oncol. 2016;39(2):114‐119. doi:10.1097/COC.0000000000000025
Oeffinger KC, Ford JS, Moskowitz CS, et al. Promoting breast cancer surveillance: the EMPOWER study, a randomized clinical trial in the Childhood Cancer Survivor Study. J Clin Oncol. 2019 Aug 20;37(24):2131‐2140. doi:10.1200/JCO.19.00547
Ford JS, Tonorezos ES, Mertens AC, et al. Barriers and facilitators of risk‐based health care for adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. Cancer. 2020;126(3):619‐627. doi:10.1002/cncr.32568
Mobley EM, Moke DJ, Milam J, et al. Interventions to address disparities and barriers to pediatric cancer survivorship care: a scoping review. J Cancer Surviv. 2022;16(3):667‐676. doi:10.1007/s11764‐021‐01060‐4
Casillas J, Oeffinger KC, Hudson MM, et al. Identifying predictors of longitudinal decline in the level of medical care received by adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. Health Serv Res. 2015;50(4):1021‐1042. doi:10.1111/1475‐6773.12282
Mirzaei S, Martínez JM, Chow EJ, et al. Association analysis of self‐reported outcomes with a validated subset. Stat Med. 2024;43(4):642‐655. doi:10.1002/sim.9976