Sustainable bioinspired materials for regenerative medicine: balancing toxicology, environmental impact, and ethical considerations.

Bioinspired Materials Environmental Impact Ethical Considerations Regenerative Medicine Toxicology

Journal

Biomedical materials (Bristol, England)
ISSN: 1748-605X
Titre abrégé: Biomed Mater
Pays: England
ID NLM: 101285195

Informations de publication

Date de publication:
10 Oct 2024
Historique:
medline: 11 10 2024
pubmed: 11 10 2024
entrez: 10 10 2024
Statut: aheadofprint

Résumé

The pursuit of sustainable bioinspired materials in regenerative medicine necessitates a delicate equilibrium between scientific innovation, ethical mindfulness, and environmental responsibility. This abstract encapsulates the essence of a comprehensive perspective paper that explores the intricate interplay of toxicology, environmental impact, and ethical considerations in the realm of bioinspired materials. As the regenerative medicine landscape continues to evolve, the evaluation of biocompatibility and safety of bioinspired materials emerges as a critical concern. This paper delves into the multidimensional aspects of toxicity assessment, encompassing cytotoxicity, genotoxicity, and immunotoxicity analyses. Moreover, it sheds light on the challenging task of evaluating the environmental repercussions of these materials, elucidating methodologies such as life cycle assessment, biodegradability testing, and sustainable design approaches. Amid these scientific endeavors, the ethical dimensions of bioinspired material development remain paramount. The paper navigates the complex web of international regulations and ethical frameworks guiding medical materials, emphasizing the importance of aligning innovation with ethical standards. Furthermore, the abstract highlights the envisioned future directions and challenges in toxicology techniques, computational modeling, and holistic evaluation, culminating in a holistic understanding of the synergistic interplay between sustainable bioinspired materials, toxicity assessment, environmental stewardship, and ethical deliberation.&#xD.

Identifiants

pubmed: 39389102
doi: 10.1088/1748-605X/ad85bb
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024 IOP Publishing Ltd. All rights, including for text and data mining, AI training, and similar technologies, are reserved.

Auteurs

Ajay Vikram Singh (AV)

Department of Chemical and Product Safety, German Federal Institute for Risk Assessment, Maxdohrnstrasse 8-10, Berlin, 10589, GERMANY.

Vaisali Chandrasekar (V)

Department of Surgery, Hamad Medical Corporation (HMC), Hamad Medical Corporation (HMC), Doha, Doha, 3050, QATAR.

Varsha M Prabhu (VM)

Department of Surgery, Hamad Medical Corporation (HMC), Hamad Medical Corporation (HMC), Doha, Doha, 3050, QATAR.

Jolly Bhadra (J)

Qatar University Young Research centre (QUYRC) Qatar University 2053, QUYRC, Doha, 2053, QATAR.

Peter Laux (P)

Department of Chemical and Product Safety, German Federal Institute for Risk Assessment, Maxdohrnstrasse 8-10, Berlin, 10589, GERMANY.

Preeti Bhardwaj (P)

Department of Chemical and Product Safety, German Federal Institute for Risk Assessment, Maxdohrnstrasse 8-10, Berlin, 10589, GERMANY.

Abdulla A Al-Ansari (AA)

Department of Surgery, Hamad Medical Corporation (HMC), HMC, Doha, 3050, QATAR.

Omar M Aboumarzouk (OM)

Department of Surgery, Hamad Medical Corporation, HMC, Doha, Ad Dawhah, 2050, QATAR.

Andreas Luch (A)

Department of Chemical and Product Safety, German Federal Institute for Risk Assessment, Maxdohrnstrasse 8-10, Berlin, 10589, GERMANY.

Sarada Prasad Dakua (SP)

Department of Surgery, Hamad Medical Corporation (HMC), HMC, Doha, 3050, QATAR.

Classifications MeSH