Neurocutaneous disorders identified in the neonatal period and infancy: Hypomelanosis of Ito.
Blaschko lines
Epilepsy
Genetic mosaicism
Hypomelanosis of Ito
Neurocutaneous disorder
Journal
Seminars in pediatric neurology
ISSN: 1558-0776
Titre abrégé: Semin Pediatr Neurol
Pays: United States
ID NLM: 9441351
Informations de publication
Date de publication:
Oct 2024
Oct 2024
Historique:
received:
27
06
2024
revised:
08
09
2024
accepted:
10
09
2024
medline:
11
10
2024
pubmed:
11
10
2024
entrez:
10
10
2024
Statut:
ppublish
Résumé
Hypomelanosis of Ito is a rare neurocutaneous disorder named after the Japanese dermatologist Minoru Ito who in 1952 described the condition. Characteristically, the hypopigmented lesions in this condition follow Blaschko lines. Extracutaneous manifestations of the disease include neurological, musculoskeletal, cardiac, endocrine, and renal signs and symptoms. The most common neurological manifestation is cognitive impairment. Seizures, developmental delay, and abnormal tone can also be present. In this review we discuss the condition's clinical presentations, its diagnostic criteria, and consensus recommendations.
Identifiants
pubmed: 39389656
pii: S1071-9091(24)00040-8
doi: 10.1016/j.spen.2024.101154
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
101154Informations de copyright
Copyright © 2024. Published by Elsevier Inc.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.