[An invasive cutaneous aspergillosis during a granulomatosis with polyangiitis].
Une aspergillose cutanée invasive au cours d’une granulomatose avec polyangéite.
ANCA
Aspergillose cutanée invasive
Biopsie cutanée
Immunodeficiency
Immunodépression
Invasive cutaneous aspergillosis
Skin biopsy
Vascularite
Vasculitis
Journal
La Revue de medecine interne
ISSN: 1768-3122
Titre abrégé: Rev Med Interne
Pays: France
ID NLM: 8101383
Informations de publication
Date de publication:
09 Oct 2024
09 Oct 2024
Historique:
received:
19
09
2023
revised:
10
09
2024
accepted:
16
09
2024
medline:
11
10
2024
pubmed:
11
10
2024
entrez:
10
10
2024
Statut:
aheadofprint
Résumé
Aspergillosis is an opportunistic infection that can complicate any situation of immunosuppression. The primary manifestations are pulmonary, and more rarely, in cases of severe immunosuppression, the infection can become invasive with extra-pulmonary involvement. We report the case of a 76-year-old female patient, experiencing a relapse of granulomatosis with polyangiitis treated with corticosteroids, rituximab and cyclophosphamide, who presented with diffuse erythematous nodular skin lesions. A biopsy with histological analysis confirmed a diagnosis of invasive cutaneous aspergillosis. Treatment with voriconazole led to a favorable outcome. The appearance of skin lesions in an inflammatory context in a patient receiving immunosuppressive therapy should prompt a comprehensive microbiological assessment for opportunistic pathogens, as well as a skin biopsy to investigate for invasive cutaneous aspergillosis.
Identifiants
pubmed: 39389853
pii: S0248-8663(24)00767-7
doi: 10.1016/j.revmed.2024.09.005
pii:
doi:
Types de publication
English Abstract
Journal Article
Langues
fre
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.