Investigation of the distribution of inguinal lymph nodes and delineation of the inguinal clinical target volume using
Humans
Fluorodeoxyglucose F18
Positron Emission Tomography Computed Tomography
/ methods
Female
Male
Middle Aged
Lymph Nodes
/ diagnostic imaging
Aged
Adult
Lymphatic Metastasis
/ diagnostic imaging
Aged, 80 and over
Inguinal Canal
/ diagnostic imaging
Pelvic Neoplasms
/ diagnostic imaging
Radiopharmaceuticals
Groin
/ diagnostic imaging
Young Adult
18F-FDG PET/CT
Clinical target volume
Inguinal lymph nodes metastases
Intensity-modulated radiotherapy
Pelvic and perineal cancer
Journal
BMC cancer
ISSN: 1471-2407
Titre abrégé: BMC Cancer
Pays: England
ID NLM: 100967800
Informations de publication
Date de publication:
10 Oct 2024
10 Oct 2024
Historique:
received:
23
07
2024
accepted:
01
10
2024
medline:
11
10
2024
pubmed:
11
10
2024
entrez:
10
10
2024
Statut:
epublish
Résumé
Radiotherapy is a crucial treatment modality for pelvic cancers, but uncertainties persist in defining the clinical target volume (CTV) for the inguinal lymphatic drainage region. Suboptimal CTV delineation may compromise treatment efficacy and result in subpar disease control. This study aimed to investigate and map the distribution of lymph node metastases (LNM) in the groin area to facilitate an improved and detailed CTV definition using Inguinal LNM in patients with biopsy-proven pelvic malignancies were identified using In this study, 500 positive LNM were identified by Using
Identifiants
pubmed: 39390445
doi: 10.1186/s12885-024-13015-w
pii: 10.1186/s12885-024-13015-w
doi:
Substances chimiques
Fluorodeoxyglucose F18
0Z5B2CJX4D
Radiopharmaceuticals
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1254Informations de copyright
© 2024. The Author(s).
Références
Zaren HA, Copeland EM. 3rd. Inguinal node metastases. Cancer. 1978;41:919–23.
doi: 10.1002/1097-0142(197803)41:3<919::AID-CNCR2820410320>3.0.CO;2-A
pubmed: 638977
NCCN. NCCN Clinical Practice Guidelines in Oncology - Cervical Cancer. Version 3.2024.
NCCN. NCCN Clinical Practice Guidelines in Oncology - Colon Cancer. Version 4.2024.
Wortman BG, Post CCB, Powell ME, Khaw P, Fyles A, D’Amico R, et al. Radiation Therapy techniques and Treatment-related toxicity in the PORTEC-3 trial: comparison of 3-Dimensional Conformal Radiation Therapy Versus Intensity-Modulated Radiation Therapy. Int J Radiat Oncol Biol Phys. 2022;112:390–9.
doi: 10.1016/j.ijrobp.2021.09.042
pubmed: 34610387
Caravatta L, Mantello G, Valvo F, Franco P, Gasparini L, Rosa C et al. Radiotherapy with intensity-modulated (IMRT) techniques in the treatment of anal carcinoma (RAINSTORM): a multicenter study on behalf of AIRO (Italian association of radiotherapy and clinical oncology) gastrointestinal study group. Cancers (Basel). 2021;13.
Taylor A, Rockall AG, Reznek RH, Powell ME. Mapping pelvic lymph nodes: guidelines for delineation in intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys. 2005;63:1604–12.
doi: 10.1016/j.ijrobp.2005.05.062
pubmed: 16198509
Ng M, Leong T, Chander S, Chu J, Kneebone A, Carroll S, et al. Australasian gastrointestinal trials Group (AGITG) contouring atlas and planning guidelines for intensity-modulated radiotherapy in anal cancer. Int J Radiat Oncol Biol Phys. 2012;83:1455–62.
doi: 10.1016/j.ijrobp.2011.12.058
pubmed: 22401917
Myerson RJ, Garofalo MC, El Naqa I, Abrams RA, Apte A, Bosch WR, et al. Elective clinical target volumes for conformal therapy in anorectal cancer: a radiation therapy oncology group consensus panel contouring atlas. Int J Radiat Oncol Biol Phys. 2009;74:824–30.
doi: 10.1016/j.ijrobp.2008.08.070
pubmed: 19117696
Valentini V, Gambacorta MA, Barbaro B, Chiloiro G, Coco C, Das P, et al. International consensus guidelines on clinical target volume delineation in rectal cancer. Radiother Oncol. 2016;120:195–201.
doi: 10.1016/j.radonc.2016.07.017
pubmed: 27528121
Muirhead RAR, Gilbert D, Harrison M, Glynne-Jones R, Sebag-Montefiore D, Hawkins MA. National Guidance for IMRT in Anal Cancer. 2016.
Gaffney DK, King B, Viswanathan AN, Barkati M, Beriwal S, Eifel P, et al. Consensus Recommendations for Radiation Therapy Contouring and Treatment of Vulvar Carcinoma. Int J Radiat Oncol Biol Phys. 2016;95:1191–200.
doi: 10.1016/j.ijrobp.2016.02.043
pubmed: 27130794
pmcid: 5189987
Lee NY, Lu JJ, Jia-de J. Target Volume Delineation and Field Setup2013.
Mai SK, Welzel G, Hermann B, Wenz F, Haberkorn U, Dinter DJ. Can the radiation dose to CT-enlarged but FDG-PET-negative inguinal lymph nodes in anal cancer be reduced? Strahlenther Onkol. 2009;185:254–9.
doi: 10.1007/s00066-009-1944-5
pubmed: 19370429
Bipat S, Fransen GA, Spijkerboer AM, van der Velden J, Bossuyt PM, Zwinderman AH, et al. Is there a role for magnetic resonance imaging in the evaluation of inguinal lymph node metastases in patients with vulva carcinoma? Gynecol Oncol. 2006;103:1001–6.
doi: 10.1016/j.ygyno.2006.06.009
pubmed: 16859737
Rufini V, Garganese G, Ieria FP, Pasciuto T, Fragomeni SM, Gui B, et al. Diagnostic performance of preoperative [(18)F]FDG-PET/CT for lymph node staging in vulvar cancer: a large single-centre study. Eur J Nucl Med Mol Imaging. 2021;48:3303–14.
doi: 10.1007/s00259-021-05257-8
pubmed: 33619601
pmcid: 8426310
Jakobsen JK, Frahm Nielsen T, Ipsen P, Albrecht-Beste E, Cardoso Costa J, Alslev L, et al. DaPeCa-7: comparative assessment of fluorodeoxyglucose positron emission tomography/computed tomography (CT) and conventional diagnostic CT in diagnosis of lymph node metastases, distant metastases and incidental findings in patients with invasive penile cancer. BJU Int. 2021;127:254–62.
doi: 10.1111/bju.15206
pubmed: 33448605
Mahmud A, Poon R, Jonker D. PET imaging in anal canal cancer: a systematic review and meta-analysis. Br J Radiol. 2017;90:20170370.
doi: 10.1259/bjr.20170370
pubmed: 28972796
pmcid: 6047643
Lee SW, Kim SJ. Diagnostic performance of 18F-FDG PET/CT for Lymph Node staging in Penile Cancer. Clin Nucl Med. 2022;47:402–8.
doi: 10.1097/RLU.0000000000004081
pubmed: 35143458
Salem AE, Fine GC, Covington MF, Koppula BR, Wiggins RH, Hoffman JM et al. PET-CT in clinical adult Oncology-IV. Gynecologic and genitourinary malignancies. Cancers (Basel). 2022;14.
Fonti R, Conson M, Del Vecchio S. PET/CT in radiation oncology. Semin Oncol. 2019;46:202–9.
doi: 10.1053/j.seminoncol.2019.07.001
pubmed: 31378377
Bontumasi N, Jacobson JA, Caoili E, Brandon C, Kim SM, Jamadar D. Inguinal lymph nodes: size, number, and other characteristics in asymptomatic patients by CT. Surg Radiol Anat. 2014;36:1051–5.
doi: 10.1007/s00276-014-1255-0
pubmed: 24435023
Padhani AR. Lymph nodes. In: Nicholson T(ed). Recommendations for cross-sectional imaging in cancer management, Second edition: London: The Royal College of Radiologists; 2014.
Ganeshalingam S, Koh DM. Nodal staging. Cancer Imaging. 2009;9:104–11.
doi: 10.1102/1470-7330.2009.0017
pubmed: 20080453
pmcid: 2821588
Shim SS, Lee KS, Kim BT, Chung MJ, Lee EJ, Han J, et al. Non-small cell lung cancer: prospective comparison of integrated FDG PET/CT and CT alone for preoperative staging. Radiology. 2005;236:1011–9.
doi: 10.1148/radiol.2363041310
pubmed: 16014441
Du XL, Jiang T, Sheng XG, Li QS, Wang C, Yu H. PET/CT scanning guided intensity-modulated radiotherapy in treatment of recurrent ovarian cancer. Eur J Radiol. 2012;81:3551–6.
doi: 10.1016/j.ejrad.2012.03.016
pubmed: 22521528
Eraj S, Sher DJ. PET/CT: Radiation Therapy Planning in Head and Neck Cancer. PET Clin. 2022;17:297–305.
doi: 10.1016/j.cpet.2021.12.007
pubmed: 35256302
Jani AB, Schreibmann E, Goyal S, Halkar R, Hershatter B, Rossi PJ, et al. (18)F-fluciclovine-PET/CT imaging versus conventional imaging alone to guide postprostatectomy salvage radiotherapy for prostate cancer (EMPIRE-1): a single centre, open-label, phase 2/3 randomised controlled trial. Lancet. 2021;397:1895–904.
doi: 10.1016/S0140-6736(21)00581-X
pubmed: 33971152
pmcid: 8279109
Konert T, Vogel WV, Paez D, Polo A, Fidarova E, Carvalho H, et al. Introducing FDG PET/CT-guided chemoradiotherapy for stage III NSCLC in low- and middle-income countries: preliminary results from the IAEA PERTAIN trial. Eur J Nucl Med Mol Imaging. 2019;46:2235–43.
doi: 10.1007/s00259-019-04421-5
pubmed: 31367906
pmcid: 6717604
Gupta T, Beriwal S. PET/CT-guided radiation therapy planning: from present to the future. Indian J Cancer. 2010;47:126–33.
doi: 10.4103/0019-509X.63000
pubmed: 20448373
Kim CH, Olson AC, Kim H, Beriwal S. Contouring inguinal and femoral nodes; how much margin is needed around the vessels? Pract Radiat Oncol. 2012;2:274–8.
doi: 10.1016/j.prro.2011.12.005
pubmed: 24674164
Rao AS, Rajmanickam K, Narayanan GS. Study of distribution of inguinal nodes around the femoral vessels and contouring of inguinal nodes. J Cancer Res Ther. 2015;11:575–9.
doi: 10.4103/0973-1482.163735
pubmed: 26458584
Garda AE, Navin PJ, Merrell KW, Martenson JA, Neben Wittich MA, Haddock MG, et al. Patterns of inguinal lymph node metastases in anal canal cancer and recommendations for elective clinical target volume (CTV) delineation. Radiother Oncol. 2020;149:128–33.
doi: 10.1016/j.radonc.2020.05.018
pubmed: 32417349
Mittal R, Krishnatry R, Maitre P, Murthy V. Recommendations and clinical validation of Inguinal Clinical Target volume delineation in Penile Cancer. Int J Radiat Oncol Biol Phys. 2021;111:741–53.
doi: 10.1016/j.ijrobp.2021.06.027
pubmed: 34174355
Chang Y, Li G, Yang Z, Han G, Li X, Zhao Y, et al. Inguinal nodal clinical target volume delineation based on analysis of anatomical locations of normal and metastatic lymph nodes in pelvic malignant tumors. Radiother Oncol. 2023;183:109634.
doi: 10.1016/j.radonc.2023.109634
pubmed: 36963443
Wright JL, Patil SM, Temple LK, Minsky BD, Saltz LB, Goodman KA. Squamous cell carcinoma of the anal canal: patterns and predictors of failure and implications for intensity-modulated radiation treatment planning. Int J Radiat Oncol Biol Phys. 2010;78:1064–72.
doi: 10.1016/j.ijrobp.2009.09.029
pubmed: 20350793
Nilsson MP, Nilsson ED, Johnsson A, Leon O, Gunnlaugsson A, Scherman J. Patterns of recurrence in anal cancer: a detailed analysis. Radiat Oncol. 2020;15:125.
doi: 10.1186/s13014-020-01567-7
pubmed: 32460785
pmcid: 7251738
Koh WJ, Chiu M, Stelzer KJ, Greer BE, Mastras D, Comsia N, et al. Femoral vessel depth and the implications for groin node radiation. Int J Radiat Oncol Biol Phys. 1993;27:969–74.
doi: 10.1016/0360-3016(93)90476-C
pubmed: 8244831