P-Stereodefined morpholino dinucleoside 3',5'-phosphorothioates.

Journal

Organic & biomolecular chemistry
ISSN: 1477-0539
Titre abrégé: Org Biomol Chem
Pays: England
ID NLM: 101154995

Informations de publication

Date de publication:
11 Oct 2024
Historique:
medline: 11 10 2024
pubmed: 11 10 2024
entrez: 11 10 2024
Statut: aheadofprint

Résumé

Here, we present for the first time the synthesis of P-stereodefined morpholino phosphorothioate analogs by using a modified 1,3,2-oxathiaphospholane method (OTP method) and provide valuable structural insights into their stereochemistry.

Identifiants

DOI: 10.1039/d4ob01437e PMID: 39392463
pubmed: 39392463
doi: 10.1039/d4ob01437e
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Katarzyna Jastrzębska (K)

Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Department of Bioorganic Chemistry, Sienkiewicza 112, 90-363 Łódź, Poland. katarzyna.jastrzebska@cbmm.lodz.pl.
ORCID: 0000-0003-3979-3186

Patrycja Antończyk (P)

Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Department of Bioorganic Chemistry, Sienkiewicza 112, 90-363 Łódź, Poland. katarzyna.jastrzebska@cbmm.lodz.pl.

Rafał Dolot (R)

Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Department of Bioorganic Chemistry, Sienkiewicza 112, 90-363 Łódź, Poland. katarzyna.jastrzebska@cbmm.lodz.pl.

Classifications MeSH