Assessing inter-ocular fixational eye movements throughout the lifespan.
Development
Drift
Fixation stability
Fixational saccades
Vergence stability
Journal
Experimental brain research
ISSN: 1432-1106
Titre abrégé: Exp Brain Res
Pays: Germany
ID NLM: 0043312
Informations de publication
Date de publication:
12 Oct 2024
12 Oct 2024
Historique:
received:
15
07
2024
accepted:
24
09
2024
medline:
12
10
2024
pubmed:
12
10
2024
entrez:
12
10
2024
Statut:
aheadofprint
Résumé
This study aims to assess fixational eye movements (FEMs) obtained under binocular and monocular viewing in normal individuals across different age groups. We recruited 68 healthy participants divided into Group 1 (children, 3-9 years, n = 20), Group 2 (adolescents, 10-19 years, n = 26), and Group 3 (adults, 20-73 years, n = 22). FEMs were collected using a high-resolution video-based tracker under 3 viewing conditions: binocular viewing (BV), monocular viewing right eye (MV_RE), and monocular viewing left eye (MV_LE). We quantified fixation stability, the frequency, amplitude, and disconjugacy of fixational saccades, and inter-saccadic drift velocity in BV, MV_RE, and MV_LE. We also computed inter-ocular fixation stability under binocular viewing and monocular viewing in the 3 groups. Fixation instability (FI) and fixational saccade amplitudes were higher in Group 1 than in Group 3 whereas inter-saccadic drifts were increased in Group 3. Vergence stability was greater in binocular viewing than in monocular viewing likely due to binocular summation in all groups. However, the fixational saccade amplitude and drift velocity of the right and left eye did not significantly differ across different viewing conditions within each group. Interestingly, the inter-ocular fixation stability ratio and vergence stability showed no significant differences between the groups. In conclusion, FEMs differ across age groups but inter-ocular FEMs are immune to the effects of age and can be a valuable parameter while evaluating FEM abnormalities in diseases like amblyopia.
Identifiants
pubmed: 39395061
doi: 10.1007/s00221-024-06936-2
pii: 10.1007/s00221-024-06936-2
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Research to Prevent Blindness
ID : Research to Prevent Blindness
Organisme : Clinical and Translational Science Collaborative of Cleveland, School of Medicine, Case Western Reserve University
ID : Clinical and Translational Science Collaborative of Cleveland, School of Medicine, Case Western Reserve University
Organisme : Lerner Research Institute, Cleveland Clinic
ID : Lerner Research Institute, Cleveland Clinic
Organisme : U.S. Department of Veterans Affairs
ID : U.S. Department of Veterans Affairs
Organisme : U.S. Department of Veterans Affairs
ID : U.S. Department of Veterans Affairs
Organisme : Cleveland Eye Bank Foundation
ID : Cleveland Eye Bank Foundation
Informations de copyright
© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
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