Autoimmune CD4

CD4(+) T cell TCF1 autoimmunity exhaustion type 1 diabetes

Journal

Immunity
ISSN: 1097-4180
Titre abrégé: Immunity
Pays: United States
ID NLM: 9432918

Informations de publication

Date de publication:
09 Oct 2024
Historique:
received: 09 05 2024
revised: 21 07 2024
accepted: 25 09 2024
medline: 14 10 2024
pubmed: 14 10 2024
entrez: 13 10 2024
Statut: aheadofprint

Résumé

Self-reactive T cells experience chronic antigen exposure but do not exhibit signs of exhaustion. Here, we investigated the mechanisms for sustained, functioning autoimmune CD4

Identifiants

pubmed: 39396521
pii: S1074-7613(24)00479-5
doi: 10.1016/j.immuni.2024.09.016
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

Auteurs

Nouf Aljobaily (N)

Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA.

Denise Allard (D)

Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA.

Bryant Perkins (B)

Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA.

Arielle Raugh (A)

Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA.

Tessa Galland (T)

Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA.

Yi Jing (Y)

Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA.

W Zac Stephens (WZ)

Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA.

Matthew L Bettini (ML)

Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA.

J Scott Hale (JS)

Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA.

Maria Bettini (M)

Department of Pathology, Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT 84112, USA. Electronic address: maria.bettini@path.utah.edu.

Classifications MeSH