Improved Automated Radiosynthesis of [
Journal
ACS omega
ISSN: 2470-1343
Titre abrégé: ACS Omega
Pays: United States
ID NLM: 101691658
Informations de publication
Date de publication:
08 Oct 2024
08 Oct 2024
Historique:
received:
25
06
2024
revised:
12
09
2024
accepted:
17
09
2024
medline:
14
10
2024
pubmed:
14
10
2024
entrez:
14
10
2024
Statut:
epublish
Résumé
Positron emission tomography imaging using radiolabeled dolutegravir (DTG) is an interesting approach to understand the biodistribution of this antiretroviral drug at HIV-1 sanctuary sites. In the course of clinical translation, we depict herein an improved and pharmaceutically compliant radiosynthesis of [
Identifiants
pubmed: 39398184
doi: 10.1021/acsomega.4c05893
pmc: PMC11465247
doi:
Types de publication
Journal Article
Langues
eng
Pagination
41732-41741Informations de copyright
© 2024 The Authors. Published by American Chemical Society.
Déclaration de conflit d'intérêts
The authors declare the following competing financial interest(s): Thomas Bonasera is employed by GSK. Chris M. Parry is employed by ViiV Healthcare and has stock/shares in GSK.