Simultaneous Pancreas-Kidney Transplant Outcomes Stratified by Autoantibodies Status and Pretransplant Fasting C-peptide.

Journal

Transplantation direct
ISSN: 2373-8731
Titre abrégé: Transplant Direct
Pays: United States
ID NLM: 101651609

Informations de publication

Date de publication:
Nov 2024
Historique:
received: 02 08 2024
revised: 26 08 2024
accepted: 04 09 2024
medline: 14 10 2024
pubmed: 14 10 2024
entrez: 14 10 2024
Statut: epublish

Résumé

Pancreatic beta cell function and islet autoantibodies classically distinguish types of diabetes (type 1 diabetes mellitus [DM] or type 2 DM). Here, we sought to evaluate simultaneous pancreas-kidney (SPK) transplant outcomes stratified by the presence or absence of beta cell function and autoantibodies. SPK recipients were eligible if pretransplant autoantibodies were measured against insulin, islet cell, or glutamic acid decarboxylase 65-kD isoform. Recipients were categorized as A One hundred eighty-three SPK recipients were included: A In SPK recipients, outcomes were similar among recipients with classic features of type 1 DM and various other types of DM.

Sections du résumé

Backgrounds UNASSIGNED
Pancreatic beta cell function and islet autoantibodies classically distinguish types of diabetes (type 1 diabetes mellitus [DM] or type 2 DM). Here, we sought to evaluate simultaneous pancreas-kidney (SPK) transplant outcomes stratified by the presence or absence of beta cell function and autoantibodies.
Methods UNASSIGNED
SPK recipients were eligible if pretransplant autoantibodies were measured against insulin, islet cell, or glutamic acid decarboxylase 65-kD isoform. Recipients were categorized as A
Results UNASSIGNED
One hundred eighty-three SPK recipients were included: A
Conclusions UNASSIGNED
In SPK recipients, outcomes were similar among recipients with classic features of type 1 DM and various other types of DM.

Identifiants

DOI: 10.1097/TXD.0000000000001721 PMID: 39399059 PMC: PMC11469883
pubmed: 39399059
doi: 10.1097/TXD.0000000000001721
pii: TXD-2024-0175
pmc: PMC11469883
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e1721

Informations de copyright

Copyright © 2024 The Author(s). Transplantation Direct. Published by Wolters Kluwer Health, Inc.

Auteurs

Sandesh Parajuli (S)

Division of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
ORCID: 0000-0003-1667-7465

Riccardo Tamburrini (R)

Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.

Fahad Aziz (F)

Division of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.

Ban Dodin (B)

Division of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.

Brad C Astor (BC)

Division of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI.

Didier Mandelbrot (D)

Division of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.

Dixon Kaufman (D)

Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.

Jon Odorico (J)

Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.
University of Wisconsin Health Transplant Center, Madison, WI.

Classifications MeSH