Enzyme-Mediated Organic Neurohybrid Synapses.

electrochemical neuromorphic organic devices glutamate sensing neuroelectronics

Journal

Advanced materials (Deerfield Beach, Fla.)
ISSN: 1521-4095
Titre abrégé: Adv Mater
Pays: Germany
ID NLM: 9885358

Informations de publication

Date de publication:
14 Oct 2024
Historique:
revised: 19 09 2024
received: 04 07 2024
medline: 15 10 2024
pubmed: 15 10 2024
entrez: 15 10 2024
Statut: aheadofprint

Résumé

The development of organic artificial synapses that exhibit biomimicry features also may enable a more seamless integration of neuroelectronic devices in the nervous system, allowing artificial neuromodulation to be perceived as natural behavior by neuronal cells. Nevertheless, the capability to interact with both electroactive and non-electroactive neurotransmitters remains a challenge since state-of-the-art devices mainly rely on the oxidation of electroactive species. Here, the study proposes an organic artificial synapse engineered to enable interaction with non-electroactive species present in the central nervous system. By integrating a conductive polymeric film functionalized with platinum nanoparticles, the device can catalyze the oxidation of electroactive molecules (i.e., H

Identifiants

pubmed: 39402777
doi: 10.1002/adma.202409614
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2409614

Subventions

Organisme : European Union's Horizon 2020 Research and Innovation Program
ID : 949478
Organisme : H2020 European Research Council
ID : 949478

Informations de copyright

© 2024 The Author(s). Advanced Materials published by Wiley‐VCH GmbH.

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Auteurs

Antonio Lobosco (A)

Institute of Biological Information Processing IBI-3, Forschungszentrum Juelich, 52428, Jülich, Germany.
Neuroelectronic Interfaces, Faculty of Electrical Engineering and IT, RWTH, 52074, Aachen, Germany.

Claudia Lubrano (C)

Institute of Biological Information Processing IBI-3, Forschungszentrum Juelich, 52428, Jülich, Germany.
Neuroelectronic Interfaces, Faculty of Electrical Engineering and IT, RWTH, 52074, Aachen, Germany.

Daniela Rana (D)

Institute of Biological Information Processing IBI-3, Forschungszentrum Juelich, 52428, Jülich, Germany.
Neuroelectronic Interfaces, Faculty of Electrical Engineering and IT, RWTH, 52074, Aachen, Germany.

Viviana Rincon Montes (VR)

Institute of Biological Information Processing IBI-3, Forschungszentrum Juelich, 52428, Jülich, Germany.

Simon Musall (S)

Institute of Biological Information Processing IBI-3, Forschungszentrum Juelich, 52428, Jülich, Germany.
Institute of Biology 2, 52074, RWTH Aachen, Aachen, Germany.
Faculty of Medicine, Institute of Experimental Epileptology and Cognition Research, University of Bonn, 53127, Bonn, Germany.

Andreas Offenhäusser (A)

Institute of Biological Information Processing IBI-3, Forschungszentrum Juelich, 52428, Jülich, Germany.

Francesca Santoro (F)

Institute of Biological Information Processing IBI-3, Forschungszentrum Juelich, 52428, Jülich, Germany.
Neuroelectronic Interfaces, Faculty of Electrical Engineering and IT, RWTH, 52074, Aachen, Germany.

Classifications MeSH