Neuralgic amyotrophy: An update in evaluation, diagnosis, and treatment approaches.

brachial neuritis neuralgic amyotrophy parsonage‐turner syndrome peripheral nerve rehabilitation

Journal

Muscle & nerve
ISSN: 1097-4598
Titre abrégé: Muscle Nerve
Pays: United States
ID NLM: 7803146

Informations de publication

Date de publication:
14 Oct 2024
Historique:
revised: 21 09 2024
received: 30 11 2023
accepted: 23 09 2024
medline: 15 10 2024
pubmed: 15 10 2024
entrez: 15 10 2024
Statut: aheadofprint

Résumé

Neuralgic amyotrophy (NA) is an underrecognized peripheral nerve disorder distinguished by severe pain followed by weakness in the distribution of one or more nerves, most commonly in the upper extremity. While classically felt to carry a favorable prognosis, updates in research have demonstrated that patients frequently endure delay in diagnosis and continue to experience long term pain, paresis, and fatigue even years after the diagnosis is made. A transition in therapeutic approach is recommended and described by this review, which emphasizes the necessity to target compensatory abnormal motor control and fatigue by focusing on motor coordination, energy conservation strategies, and behavioral change, rather than strength training which may worsen the symptoms. The development of structural hourglass-like constrictions (HGCs) on imaging can help confirm the suspected clinical diagnosis, and in association with persistent weakness and limited recovery on electrodiagnostic testing may be considered for surgical consultation. Given the complex nature of management, a multidisciplinary approach is described, which can provide an optimal level of care and support for patients with persistent symptoms from NA and allow more unified guidance of rehabilitation and surgical referrals.

Identifiants

pubmed: 39402917
doi: 10.1002/mus.28274
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024 Wiley Periodicals LLC.

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Auteurs

Joelle M Gabet (JM)

Department of Physical Medicine and Rehabilitation, MetroHealth Rehabilitation Institute, The MetroHealth System and Case Western Reserve University, Cleveland, Ohio, USA.

Noriko Anderson (N)

Department of Neurology, University of California San Francisco Medical Center and Weill Institute for Neurosciences, San Francisco, California, USA.

Jan T Groothuis (JT)

Department of Rehabilitation, Donders Institute for Brain, Cognition, and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands.

Evan R Zeldin (ER)

Department of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, Ohio, USA.

John W Norbury (JW)

Department of Neurology, Division of Physical Medicine and Rehabilitation, Texas Tech Health Sciences Center, Lubbock, Texas, USA.

Andrew S Jack (AS)

Division of Neurosurgery, University of Alberta, Edmonton, Alberta, Canada.

Line Jacques (L)

Department of Neurological Surgery, University of California San Francisco Medical Center and Weill Institute for Neurosciences, San Francisco, California, USA.

Darryl B Sneag (DB)

Department of Radiology and Imaging, Hospital for Special Surgery, New York, New York, USA.

Ann Poncelet (A)

Department of Neurology, University of California San Francisco Medical Center and Weill Institute for Neurosciences, San Francisco, California, USA.

Classifications MeSH