Targeting caspase-8/c-FLIP
CD95
FLIPin
SMAC mimetic
c-FLIP
caspase-8
cell death
complex II
Journal
Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250
Informations de publication
Date de publication:
2024
2024
Historique:
received:
26
07
2024
accepted:
13
09
2024
medline:
15
10
2024
pubmed:
15
10
2024
entrez:
15
10
2024
Statut:
epublish
Résumé
Death receptor (DR) networks are controlled by the assembly of the Death-Inducing Signaling Complex (DISC) and complex II. The family of small molecules FLIPins (FLIP interactors) were developed to target the caspase-8/c-FLIP
Identifiants
pubmed: 39403127
doi: 10.3389/fcell.2024.1471216
pii: 1471216
pmc: PMC11471875
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1471216Informations de copyright
Copyright © 2024 Hillert-Richter, König, Ivanisenko, Reinhold and Lavrik.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.