Mask wearing impacts skin barrier function and microbiome profile in sensitive skin.
Dermocosmetics
Medical mask
Sensitive skin
Skin barrier
Skin microbiome
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
16 10 2024
16 10 2024
Historique:
received:
22
07
2024
accepted:
01
10
2024
medline:
16
10
2024
pubmed:
16
10
2024
entrez:
15
10
2024
Statut:
epublish
Résumé
Mask-wearing behavior, common in the post-COVID-19 era, raises concerns for sensitive skin. This split-face study investigated mask-related changes in skin barrier function and microbiome composition among 30 female volunteers with sensitive skin and assessed the mitigating effects of a moisturizer containing biological lipids and probiotics. Skin physiological indicators (transepidermal water loss, erythema index, stratum corneum hydration, pH, temperature) of masked and unmasked areas were collected at baseline, after three hours of mask-wearing, post-tape stripping, and after 24 h, respectively. Microbiome samples collected from the masked areas before and after wearing a medical mask were analyzed with bioinformatics methods. Mask-wearing significantly weakened barrier function in both masked and adjacent unmasked areas, while reducing bacterial diversity. It was also associated with an increase in Cutibacterium (P = 0.110) and decreases in Streptococcus (P = 0.032) and Prevotella (P = 0.026) abundance. Moisturizer application prior to mask-wearing significantly reduced transepidermal water loss and erythema (both P < 0.001) and further improved erythema after 24 h (P = 0.048). These findings demonstrate that mask-wearing can disrupt the skin barrier and microbiome in individuals with sensitive skin and applying a moisturizer beforehand can mitigate mask-related discomforts by aiding barrier repair and reducing sensitivity.
Identifiants
pubmed: 39406854
doi: 10.1038/s41598-024-75072-2
pii: 10.1038/s41598-024-75072-2
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
24209Informations de copyright
© 2024. The Author(s).
Références
Javid, B., Weekes, M. P. & Matheson, N. J. Covid-19: should the public wear face masks? BMJ. 369, m1442. https://doi.org/10.1136/bmj.m1442 (2020).
doi: 10.1136/bmj.m1442
Zhao, T., Su, Q. & Hu, X. The relationships between family characteristics and undergraduate students’ COVID-19 responses: a cross-sectional study in China. Front. Public. Health. 10, 873696. https://doi.org/10.3389/fpubh.2022.873696 (2022).
doi: 10.3389/fpubh.2022.873696
Misery, L., Loser, K. & Ständer, S. Sensitive skin. J. Eur. Acad. Dermatol. Venereol.30 (Suppl 1), 2–8. https://doi.org/10.1111/jdv.13532 (2016).
doi: 10.1111/jdv.13532
Xu, F. et al. Self-declared sensitive skin in China: a community-based study in three top metropolises. J. Eur. Acad. Dermatol. Venereol.27, 370–375. https://doi.org/10.1111/j.1468-3083.2012.04648.x (2013).
doi: 10.1111/j.1468-3083.2012.04648.x
Chan, M. K. T., Sayag, M., Chavagnac, M., Taieb, C. & Misery, L. Sensitive skin in China: characteristics and burden. J. Eur. Acad. Dermatol. Venereol.35, e436–e439. https://doi.org/10.1111/jdv.17100 (2021).
doi: 10.1111/jdv.17100
Wu, Y., Wangari-Olivero, J. & Zhen, Y. A. R. T. I. C. L. E. Compromised skin barrier and sensitive skin in diverse populations. J. Drugs Dermatol.20, s17–s22. https://doi.org/10.36849/JDD.2021.589c (2021).
doi: 10.36849/JDD.2021.589c
Bosko, C. A. Skin barrier insights: from bricks and mortar to molecules and microbes. J. Drugs Dermatol.18, s63–s67 (2019).
Gheisari, M., Araghi, F., Moravvej, H., Tabary, M. & Dadkhahfar, S. Skin reactions to non-glove personal protective equipment: an emerging issue in the COVID-19 pandemic. J. Eur. Acad. Dermatol. Venereol.34, e297–e298. https://doi.org/10.1111/jdv.16492 (2020).
doi: 10.1111/jdv.16492
Hua, W. et al. Short-term skin reactions following use of N95 respirators and medical masks. Contact Dermat.83, 115–121. https://doi.org/10.1111/cod.13601 (2020).
doi: 10.1111/cod.13601
Seite, S. & Misery, L. Skin sensitivity and skin microbiota: is there a link? Exp. Dermatol.27, 1061–1064. https://doi.org/10.1111/exd.13686 (2018).
doi: 10.1111/exd.13686
Bai, Y., Wang, Y., Zheng, H., Tan, F. & Yuan, C. Correlation between facial skin microbiota and skin barriers in a Chinese female population with sensitive skin. Infect. Drug Resist.14, 219–226. https://doi.org/10.2147/IDR.S287844 (2021).
doi: 10.2147/IDR.S287844
Zhang, J. et al. Effects of wearing masks during COVID-19 pandemic on the composition and diversity of skin bacteria and fungi in medical workers. Front. Microbiol.14, 1274050. https://doi.org/10.3389/fmicb.2023.1274050 (2023).
doi: 10.3389/fmicb.2023.1274050
Montero-Vilchez, T. et al. Impact of gloves and mask use on epidermal barrier function in health care workers. Dermatitis. 32, 57–62. https://doi.org/10.1097/DER.0000000000000682 (2021).
doi: 10.1097/DER.0000000000000682
Wan, X., Lu, Q., Sun, D., Wu, H. & Jiang, G. Skin barrier damage due to prolonged mask use among healthcare workers and the general population during the COVID-19 pandemic: a prospective cross-sectional survey in China. Dermatology. 238, 218–225. https://doi.org/10.1159/000517219 (2022).
doi: 10.1159/000517219
Spigariolo, C. B., Giacalone, S., Nazzaro, G. & Maskne The epidemic within the pandemic: from diagnosis to therapy. J. Clin. Med.11, 618. https://doi.org/10.3390/jcm11030618 (2022).
doi: 10.3390/jcm11030618
Park, S. R., Han, J., Yeon, Y. M., Kang, N. Y. & Kim, E. Effect of face mask on skin characteristics changes during the COVID-19 pandemic. Skin. Res. Technol.27, 554–559. https://doi.org/10.1111/srt.12983 (2021).
doi: 10.1111/srt.12983
Feng, L. et al. Compromised skin barrier induced by prolonged face mask usage during the COVID-19 pandemic and its remedy with proper moisturization. Skin. Res. Technol.29, e13214. https://doi.org/10.1111/srt.13214 (2023).
doi: 10.1111/srt.13214
Pinto, P., Rosado, C., Parreirão, C. & Rodrigues, L. M. Is there any barrier impairment in sensitive skin? A quantitative analysis of sensitive skin by mathematical modeling of transepidermal water loss desorption curves. Skin. Res. Technol.17, 181–185. https://doi.org/10.1111/j.1600-0846.2010.00478.x (2011).
doi: 10.1111/j.1600-0846.2010.00478.x
Parnham, A., Copson, D. & Loban, T. Moisture-associated skin damage: causes and an overview of assessment, classification and management. Br. J. Nurs.29, S30–S37. https://doi.org/10.12968/bjon.2020.29.12.S30 (2020).
doi: 10.12968/bjon.2020.29.12.S30
Zheng, Y., Liang, H., Li, Z., Tang, M. & Song, L. Skin microbiome in sensitive skin: the decrease of Staphylococcus epidermidis seems to be related to female lactic acid sting test sensitive skin. J. Dermatol. Sci.97, 225–228. https://doi.org/10.1016/j.jdermsci.2019.12.004 (2020).
doi: 10.1016/j.jdermsci.2019.12.004
Huang, C. et al. Characteristics of facial skin problems and microbiome variation during wearing masks for fighting against COVID-19. J. Eur. Acad. Dermatol. Venereol.35, e853–e855. https://doi.org/10.1111/jdv.17580 (2021).
doi: 10.1111/jdv.17580
Berardesca, E. et al. Randomised, split-face study of a dermocosmetic cream containing sphingobioma xenophaga extract and Neurosensine
doi: 10.1111/srt.13735
Tan, J., Demessant, A., Le Dantec, G., Le Floc’h, C. & Kerob, D. Tolerance and efficacy of a dermocosmetic containing neurosensine
doi: 10.2147/CCID.S391890
Wang, Y. et al. Efficacy of a moisturizing cream and facial mask for alleviating skin problems associated with medical mask use: a half-face, randomized controlled study. J. Cosmet. Dermatol.23, 2097–2102. https://doi.org/10.1111/jocd.16226 (2024).
doi: 10.1111/jocd.16226
Berardesca, E., Bonfigli, A., Cartigliani, C., Kerob, D. & Tan, J. A randomized, controlled clinical trial of a dermocosmetic containing Vichy volcanic mineralizing water and probiotic fractions in subjects with rosacea associated with erythema and sensitive skin and wearing protective masks. Clin. Cosmet. Investig Dermatol.16, 71–77. https://doi.org/10.2147/CCID.S391893 (2023).
doi: 10.2147/CCID.S391893
Park, S. R. et al. Long-term effects of face masks on skin characteristics during the COVID-19 pandemic. Skin. Res. Technol.28, 153–161. https://doi.org/10.1111/srt.13107 (2022).
doi: 10.1111/srt.13107
Ding, D. M. et al. Association between lactic acid sting test scores, self-assessed sensitive skin scores and biophysical properties in Chinese females. Int. J. Cosmet. Sci.41, 398–404. https://doi.org/10.1111/ics.12550 (2019).
doi: 10.1111/ics.12550
Tao, R., Niu, Y., Guo, J., Zhong, S. & Wu, Y. The relationship between subjective skin type and skin barrier function [article in Chinese]. Clin. J. Dermatol.44, 3–6. https://doi.org/10.16761/j.cnki.1000-4963.2015.01.005 (2015).
doi: 10.16761/j.cnki.1000-4963.2015.01.005
Magoč, T. & Salzberg, S. L. FLASH: fast length adjustment of short reads to improve genome assemblies. Bioinformatics. 27, 2957–2963. https://doi.org/10.1093/bioinformatics/btr507 (2011).
doi: 10.1093/bioinformatics/btr507
Edgar, R. C. UPARSE: highly accurate OTU sequences from microbial amplicon reads. Nat. Methods. 10, 996–998. https://doi.org/10.1038/nmeth.2604 (2013).
doi: 10.1038/nmeth.2604
Quast, C. et al. The SILVA ribosomal RNA gene database project: improved data processing and web-based tools. Nucleic Acids Res.41, D590–D596. https://doi.org/10.1093/nar/gks1219 (2013).
doi: 10.1093/nar/gks1219
Edgar, R. C. MUSCLE: multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res.32, 1792–1797. https://doi.org/10.1093/nar/gkh340 (2004).
doi: 10.1093/nar/gkh340
Caporaso, J. G. et al. QIIME allows analysis of high-throughput community sequencing data. Nat. Methods. 7, 335–336. https://doi.org/10.1038/nmeth.f.303 (2010).
doi: 10.1038/nmeth.f.303