Unveiling the Role of Two Rhodopsin-like GPCR Genes in Insecticide-Resistant House Flies,
G-protein coupled receptors (GPCRs)
cytochrome P450s
gene mapping
house flies
insecticide resistance
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
02 Oct 2024
02 Oct 2024
Historique:
received:
16
08
2024
revised:
24
09
2024
accepted:
29
09
2024
medline:
16
10
2024
pubmed:
16
10
2024
entrez:
16
10
2024
Statut:
epublish
Résumé
Insecticide resistance in insects, driven by the overexpression of P450 enzymes, presents a significant challenge due to the enhanced metabolic detoxification of insecticides. Although the transcriptional regulation of P450 genes is not yet fully understood, G-protein-coupled receptor (GPCR) genes have emerged as key regulators in this process. This study is the first to associate GPCR genes with insecticide resistance in
Identifiants
pubmed: 39408947
pii: ijms251910618
doi: 10.3390/ijms251910618
pii:
doi:
Substances chimiques
Receptors, G-Protein-Coupled
0
Insecticides
0
Rhodopsin
9009-81-8
Cytochrome P-450 Enzyme System
9035-51-2
Insect Proteins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : AAES Hatch/Multistate Grants
ID : ALA015-1-10026, ALA015-1-16009