Independent repeated mutations within the alphaviruses Ross River virus and Barmah Forest virus indicates convergent evolution and past positive selection in ancestral populations despite ongoing purifying selection.

Alphavirus Barmah Forest virus Ross River virus Togaviridae convergent evolution discrete-trait analysis

Journal

Virus evolution
ISSN: 2057-1577
Titre abrégé: Virus Evol
Pays: England
ID NLM: 101664675

Informations de publication

Date de publication:
2024
Historique:
received: 30 05 2024
revised: 25 07 2024
accepted: 12 09 2024
medline: 16 10 2024
pubmed: 16 10 2024
entrez: 16 10 2024
Statut: epublish

Résumé

Ross River virus (RRV) and Barmah Forest virus (BFV) are arthritogenic arthropod-borne viruses (arboviruses) that exhibit generalist host associations and share distributions in Australia and Papua New Guinea (PNG). Using stochastic mapping and discrete-trait phylogenetic analyses, we profiled the independent evolution of RRV and BFV signature mutations. Analysis of 186 RRV and 88 BFV genomes demonstrated their viral evolution trajectories have involved repeated selection of mutations, particularly in the nonstructural protein 1 (

Identifiants

DOI: 10.1093/ve/veae080 PMID: 39411152 PMC: PMC11477980
pubmed: 39411152
doi: 10.1093/ve/veae080
pii: veae080
pmc: PMC11477980
doi:

Types de publication

Journal Article

Langues

eng

Pagination

veae080

Informations de copyright

© The Author(s) 2024. Published by Oxford University Press.

Déclaration de conflit d'intérêts

The authors declare that there are no conflicts of interest.

Auteurs

Alyssa T Pyke (AT)

Public Health Virology Laboratory, Public and Environmental Health Reference Laboratories, Department of Health, Queensland Government, P.O. Box 594, Archerfield, Coopers Plains, Queensland, Australia.
ORCID: 0000-0003-3512-4321

Daniel J Wilson (DJ)

Big Data Institute, Oxford Population Health, University of Oxford, Li Ka Shing Centre for Health Information and Discovery, Old Road Campus, Oxford OX3 7LF, United Kingdom.
Department for Continuing Education, University of Oxford, 1 Wellington Square, Oxford OX1 2JA, United Kingdom.
ORCID: 0000-0002-0940-3311

Alice Michie (A)

School of Biomedical Sciences, University of Western Australia, 35 Stirling Highway, Perth, Western Australia 6009, Australia.

John S Mackenzie (JS)

Faculty of Health Sciences, Curtin University, G.P.O. Box U1987, Bentley, Western Australia 6845, Australia.

Allison Imrie (A)

School of Biomedical Sciences, University of Western Australia, 35 Stirling Highway, Perth, Western Australia 6009, Australia.

Jane Cameron (J)

Public Health Virology Laboratory, Public and Environmental Health Reference Laboratories, Department of Health, Queensland Government, P.O. Box 594, Archerfield, Coopers Plains, Queensland, Australia.

Stephen L Doggett (SL)

NSW Health Pathology, Westmead Hospital, 166-174 Hawkesbury Road Westmead, Sydney, New South Wales 2145, Australia.
ORCID: 0000-0001-5636-627X

John Haniotis (J)

NSW Health Pathology, Westmead Hospital, 166-174 Hawkesbury Road Westmead, Sydney, New South Wales 2145, Australia.

Lara J Herrero (LJ)

Gold Coast Campus, Institute for Glycomics, Griffith University, 1 Parklands Drive, Southport, Queensland 4215, Australia.

Leon Caly (L)

Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital at the Peter Doherty Institute for Infection and Immunity, 792 Elizabeth Street, Melbourne, Victoria 3000, Australia.

Stacey E Lynch (SE)

Agriculture Victoria Research, AgriBio, Centre for AgriBioscience, 5 Ring Road, Bundoora, Victoria 3083, Australia.

Peter T Mee (PT)

Agriculture Victoria Research, AgriBio, Centre for AgriBioscience, 5 Ring Road, Bundoora, Victoria 3083, Australia.

Eugene T Madzokere (ET)

Gold Coast Campus, Institute for Glycomics, Griffith University, 1 Parklands Drive, Southport, Queensland 4215, Australia.

Ana L Ramirez (AL)

College of Public Health, Medical and Veterinary Sciences, James Cook University, P.O. Box 6811, Cairns, Queensland 4870, Australia.
Australian Institute of Tropical Health and Medicine, James Cook University, P.O. Box 6811, Cairns, Queensland 4870, Australia.
The Jackson Laboratory, 10 Discovery Drive Connecticut, Farmington, CT 06032, United States of America.

Devina Paramitha (D)

School of Chemistry and Molecular Biosciences, The University of Queensland, Bdg 68 Cooper Road, St. Lucia, Queensland 4072, Australia.

Jody Hobson-Peters (J)

School of Chemistry and Molecular Biosciences, The University of Queensland, Bdg 68 Cooper Road, St. Lucia, Queensland 4072, Australia.

David W Smith (DW)

NSW Health Pathology, Westmead Hospital, 166-174 Hawkesbury Road Westmead, Sydney, New South Wales 2145, Australia.
School of Medicine, University of Western Australia, 35 Stirling Highway, Perth, Western Australia 6009, Australia.

Richard Weir (R)

Department of Primary Industries and Fisheries, Berrimah Veterinary Laboratory, P.O. Box 3000, Darwin, Northern Territory 0801, Australia.

Mitchell Sullivan (M)

Public and Environmental Health Reference Laboratories, Department of Health, Queensland Government, P.O Box 594 Archerfield, Coopers Plains, Queensland 4108, Australia.

Julian Druce (J)

Victorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital at the Peter Doherty Institute for Infection and Immunity, 792 Elizabeth Street, Melbourne, Victoria 3000, Australia.

Lorna Melville (L)

Department of Primary Industries and Fisheries, Berrimah Veterinary Laboratory, P.O. Box 3000, Darwin, Northern Territory 0801, Australia.

Jennifer Robson (J)

Department of Microbiology and Molecular Pathology, Sullivan Nicolaides Pathology, P.O. Box 2014 Fortitude Valley, Brisbane, Queensland 4006, Australia.

Robert Gibb (R)

Serology, Pathology Queensland Central Laboratory, Royal Brisbane and Women's Hospital, 40 Butterfield Street Herston, Brisbane, Queensland 4029, Australia.

Andrew F van den Hurk (AF)

Public Health Virology Laboratory, Public and Environmental Health Reference Laboratories, Department of Health, Queensland Government, P.O. Box 594, Archerfield, Coopers Plains, Queensland, Australia.
ORCID: 0000-0001-6262-831X

Sebastian Duchene (S)

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, 792 Elizabeth Street, Melbourne, Victoria 3000, Australia.
Evolutionary Dynamics of Infectious Diseases, Department of Computational Biology, Institut Pasteur, 28 Rue du Dr Roux, Paris 75015, France.

Classifications MeSH