Adrenal ganglioneuroma with retroperitoneal lymph node metastasis: A rare scenario.


Journal

Journal of cancer research and therapeutics
ISSN: 1998-4138
Titre abrégé: J Cancer Res Ther
Pays: India
ID NLM: 101249598

Informations de publication

Date de publication:
01 Jul 2024
Historique:
received: 31 10 2022
accepted: 12 12 2022
medline: 16 10 2024
pubmed: 16 10 2024
entrez: 16 10 2024
Statut: ppublish

Résumé

Ganglioneuroma (GN) is the most differentiated and benign variant of neuroblastic tumors, most commonly located in the posterior mediastinum, followed by the retroperitoneum and adrenal gland. Children of <10 years of age are more commonly affected than adults. Though benign, GNs can very rarely metastasize to regional lymph nodes or distant sites like liver, bone, spleen, and soft tissues. Metastatic lesions are assumed to represent neuroblastomas in which the metastasis and the primary tumor, both have matured. This differentiation can occur spontaneously or after treatment. We present a primary ganglioneuroma of adrenal gland in a 4-year-old child with nodal metastasis, without any blastemal component at any site.

Identifiants

pubmed: 39412939
doi: 10.4103/jcrt.jcrt_2280_22
pii: 01363817-202420050-00053
doi:

Types de publication

Case Reports Letter Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1647-1649

Informations de copyright

Copyright © 2024 Copyright: © 2024 Journal of Cancer Research and Therapeutics.

Références

Patel RD, Vanikar AV, Trivedi HL. Non-functional adrenal gland Ganglioneuroma masquerading as chronic calculus cholecystitis. J Assoc Physicians India 2015;63:80–81.
Cullinane C, Shimada H, Jarzembowski JA. Ganglioneuroma. WHO Classification of Tumours Editorial Board. Endocrine and Neuroendocrine Tumours Lyon (France) International Agency for Research on Cancer 2022 (WHO Classification of Tumours Series, 5th ed.; vol. 8) Available from:https://publications.iarc.fr/610.
DasGupta S, Das RN, Mishra PK, Chatterjee U, Datta C. Metastatic ganglioneuroma:A misnomer. Indian J Pathol Microbiol 2014;57:445–6.
Goldblum JR, Folpe AL, Weiss SW. Enzinger and Weiss's Soft Tissue Tumors 6th ed Philadelphia Elsevier Saunders 2014.
Shetty PK, Balaiah K, Gnana Prakash S, Shetty PK. Ganglioneuroma always a histopathological diagnosis. Online J Health Allied Scs 2010;9:19.
Singh J, Priyadarshi VK, Pandey PK, Vijay MK, Pal DK, Kundu A. Retroperitoneal ganglioneuroma. APSP J Case Rep 2013;4:8.
Oderda M, Cattaneo E, Soria F, Barreca A, Chiusa L, Morelli B, et al. Adrenal ganglioneuroma with multifocal retroperitoneal extension:A challenging diagnosis. Sci World J 2011;11:1548–53.
Karki S, Sinha AK, Upadhyaya P, Agarwal M, Pradhan A, Paudyal P, et al. Retroperitoneal ganglioneuroma. Journal of BP Koirala Institute of Health Sciences 2012;10:147–9.

Auteurs

Meenakshi Kamboj (M)

Department of Pathology, Rajiv Gandhi Cancer Institute and Research Center, Delhi, India.

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