Living histopathology - interrogation of ocular tissues by light: a celebration of the slit-lamp and a repertoire of clinical techniques.

Journal

Eye (London, England)

ISSN: 1476-5454

Titre abrégé: Eye (Lond)

Pays: England

ID NLM: 8703986

Informations de publication

Date de publication:
16 Oct 2024

Historique:

received: 09 02 2024

accepted: 07 05 2024

revised: 27 03 2024

medline: 17 10 2024

pubmed: 17 10 2024

entrez: 16 10 2024

Statut: aheadofprint

Résumé

The evolution of the slit-lamp microscope has enabled ophthalmologists to examine the transparent tissues of the eye with histological detail. This paper considers the history and optics of the slit-lamp. Optical sectioning and retro-illumination are discussed; particularly, effective placement of the reflected light beam. A variety of less conventional slit-lamp examination techniques is described. These include remote dark-field retro-illumination, examination through refractive surfaces (particularly, meniscus retro-illumination to demonstrate tear cells and non-contact corneal endothelial specular microscopy), location of vitreous abnormalities by parallax, expanding radial cords of vitreous cells in lymphoma, mirror examination of the superior fornix and corneal epithelial folds in ocular hypotension. It concludes with brief discussions about haemoglobin video imaging, semi-quantification of aqueous outflow volume by aqueous column cross-section area, and autofocus for video-microscopy. 摘要: 裂隙灯显微镜的发展使眼科医生能够检查眼部透明组织的组织学细节。本文阐述了裂隙灯的历史和光学原理, 讨论了光学切片和反向照明, 尤其是反射光束的有效设置。本文描述了多种非常规裂隙灯检查技术。其中包括远程暗视野逆行照射、透过屈光面进行检查(尤其是凹凸透镜逆行照射以显示泪液细胞和非接触式角膜内皮镜检查)、通过视差定位玻璃体异常、淋巴瘤患者玻璃体细胞放射束扩张、低眼压时上穹隆和角膜上皮的皱褶。本文简要讨论了血红蛋白视频成像、利用水柱横截面积半定量测定房水流出量, 以及视频显微镜自动调焦。.

Autres résumés

Type: Publisher (chi)

摘要: 裂隙灯显微镜的发展使眼科医生能够检查眼部透明组织的组织学细节。本文阐述了裂隙灯的历史和光学原理, 讨论了光学切片和反向照明, 尤其是反射光束的有效设置。本文描述了多种非常规裂隙灯检查技术。其中包括远程暗视野逆行照射、透过屈光面进行检查(尤其是凹凸透镜逆行照射以显示泪液细胞和非接触式角膜内皮镜检查)、通过视差定位玻璃体异常、淋巴瘤患者玻璃体细胞放射束扩张、低眼压时上穹隆和角膜上皮的皱褶。本文简要讨论了血红蛋白视频成像、利用水柱横截面积半定量测定房水流出量, 以及视频显微镜自动调焦。.

Identifiants

DOI: 10.1038/s41433-024-03139-5 PMID: 39414939

pubmed: 39414939

doi: 10.1038/s41433-024-03139-5

pii: 10.1038/s41433-024-03139-5

doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

Informations de copyright

Références

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