Effect of Sinetrol

Fat loss Gut microbiota Metabolism Obesity Polyphenols

Journal

Nutrition & metabolism
ISSN: 1743-7075
Titre abrégé: Nutr Metab (Lond)
Pays: England
ID NLM: 101231644

Informations de publication

Date de publication:
16 Oct 2024
Historique:
received: 06 02 2024
accepted: 16 09 2024
medline: 17 10 2024
pubmed: 17 10 2024
entrez: 16 10 2024
Statut: epublish

Résumé

Sinetrol In this open label study, we evaluated the effect of Sinetrol We observed HDL, HbA1C, LDL and leptin improved significantly over 16 weeks, irrespective of the dosage. There was a trend for decrease in visceral adipose tissue (VAT), BMI over time and body weight displayed a trend for dose dependent decrease. Eubacterium xylanophilum, Ruminococcacea UCG-004 genus which increased in HD and LD respectively were negatively associated to VAT. Both doses increased butyrate producers such as Eubacterium ruminantium and Ruminococcaceae NK4A214 genus. Overall chronic supplementation of Sinetrol

Sections du résumé

BACKGROUND BACKGROUND
Sinetrol
METHODS METHODS
In this open label study, we evaluated the effect of Sinetrol
RESULTS RESULTS
We observed HDL, HbA1C, LDL and leptin improved significantly over 16 weeks, irrespective of the dosage. There was a trend for decrease in visceral adipose tissue (VAT), BMI over time and body weight displayed a trend for dose dependent decrease. Eubacterium xylanophilum, Ruminococcacea UCG-004 genus which increased in HD and LD respectively were negatively associated to VAT. Both doses increased butyrate producers such as Eubacterium ruminantium and Ruminococcaceae NK4A214 genus.
CONCLUSIONS CONCLUSIONS
Overall chronic supplementation of Sinetrol

Identifiants

pubmed: 39415279
doi: 10.1186/s12986-024-00851-7
pii: 10.1186/s12986-024-00851-7
doi:

Banques de données

ClinicalTrials.gov
['NCT03823196']

Types de publication

Journal Article

Langues

eng

Pagination

83

Informations de copyright

© 2024. The Author(s).

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Auteurs

Jananee Muralidharan (J)

Fytexia, ZAE via Europa-3 rue d'Athènes, 34350, Vendres, France.

Cindy Romain (C)

Fytexia, ZAE via Europa-3 rue d'Athènes, 34350, Vendres, France.

Linda Chung (L)

Research Center for High Performance Sport-UCAM Universidad Católica de Murcia, Murcia, Spain.

Pedro Alcaraz (P)

Research Center for High Performance Sport-UCAM Universidad Católica de Murcia, Murcia, Spain.

Francisco Javier Martínez-Noguera (FJ)

Research Center for High Performance Sport-UCAM Universidad Católica de Murcia, Murcia, Spain.

Mayoura Keophiphath (M)

DIVA Expertise, Centre Pierre Potier, 1 place Pierre Potier, 31100, Toulouse, France.

Benjamin Lelouvier (B)

VAIOMER, 516 Rue Pierre et Marie Curie, 31670, Labège, France.

Patricia Ancel (P)

INSERM, INRA, C2VN, Aix Marseille Univ, Marseille, France.

Benedicte Gaborit (B)

INSERM, INRA, C2VN, Aix Marseille Univ, Marseille, France.

Julien Cases (J)

Fytexia, ZAE via Europa-3 rue d'Athènes, 34350, Vendres, France. jcases@fytexia.com.

Classifications MeSH