Effect of Silymarin on Expression of micro-RNA-21 and Matrix Metalloproteinase (MMP) 2 and 9 and Tissue Inhibitors of Matrix Metalloproteinase (TIMP) 1 and 2 in Hepatocellular Carcinoma Cell Line (HepG2).
Apoptosis
Cancer
Gene Expression
Hepatocellular Carcinoma
Journal
Medical journal of the Islamic Republic of Iran
ISSN: 1016-1430
Titre abrégé: Med J Islam Repub Iran
Pays: Iran
ID NLM: 8910777
Informations de publication
Date de publication:
2024
2024
Historique:
received:
07
11
2023
medline:
17
10
2024
pubmed:
17
10
2024
entrez:
17
10
2024
Statut:
epublish
Résumé
Silymarin is a flavonolignan that has various medicinal properties such as liver protection, antioxidant, anti-inflammatory, anti-cancer and heart protection activities. The aim of this study was to investigate the effect of silymarin on the expression level of An The significant up-regulations consisted of The present study showed that silymarin could affect the HepG2 cell line at the gene expression level
Sections du résumé
Background
UNASSIGNED
Silymarin is a flavonolignan that has various medicinal properties such as liver protection, antioxidant, anti-inflammatory, anti-cancer and heart protection activities. The aim of this study was to investigate the effect of silymarin on the expression level of
Methods
UNASSIGNED
An
Results
UNASSIGNED
The significant up-regulations consisted of
Conclusion
UNASSIGNED
The present study showed that silymarin could affect the HepG2 cell line at the gene expression level
Identifiants
pubmed: 39416370
doi: 10.47176/mjiri.38.78
pmc: PMC11480674
doi:
Types de publication
Journal Article
Langues
eng
Pagination
78Informations de copyright
© 2024 Iran University of Medical Sciences.
Déclaration de conflit d'intérêts
The authors declare that they have no competing interests.