A Comparative Study of Skeletal Muscle Relaxant Effects of Thiocolchicoside, Diazepam and Their Combination in Wistar Rats Using the Rotarod Apparatus.

Introduction Thiocolchicoside (THC) is a semi-synthetic derivative of colchicoside and a naturally occurring compound in the seeds of the

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Human subjects: All authors have confirmed that this study did not involve human participants or tissue. Animal subjects: The Institutional Animal Ethics Committee of Krishna Vishwa Vidyapeeth (Deemed to Be University) Reg. No. 255/PO/REBi/S/2000/CPCSEA (IAEC Approval no. IAEC/KIMS/2021/1) provided approval. Guidelines of the Indian National Science Academy (INSA) and the Committee for Control and Supervision of Experiments on Animals (CCSEA) at the Central Animal House, KIMSDU, were followed during the study Issued protocol number 013/2020-21. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.