"Therapeutic advancements in nanomedicine: The multifaceted roles of silver nanoparticles".

AgNps Anti-inflammation Anticancer Biomedical applications Nanotechnology Reactive oxygen species

Journal

Biotechnology notes (Amsterdam, Netherlands)
ISSN: 2665-9069
Titre abrégé: Biotechnol Notes
Pays: Netherlands
ID NLM: 9918900337606676

Informations de publication

Date de publication:
2024
Historique:
received: 25 03 2024
revised: 31 05 2024
accepted: 31 05 2024
medline: 17 10 2024
pubmed: 17 10 2024
entrez: 17 10 2024
Statut: epublish

Résumé

Nanotechnology has the advantages of enhanced bioactivity, reduced toxicity, target specificity, and sustained release and NPs can penetrate cell membranes. The small size of silver nanoparticles, AgNPs, large surface area, and unique physicochemical properties contribute to cell lysis and increased permeability of cell membranes used in the field of biomedicine. Functional precursors integrate with phytochemicals to create distinctive therapeutic properties and the stability of the nanoparticles can be enhanced by Surface coatings and encapsulation methods, The current study explores the various synthesis methods and characterization techniques of silver nanoparticles (AgNPs) and highlights their intrinsic activity in therapeutic applications, Anti-cancer activity noted at a concentration range of 5-50 μg/ml and angiogenesis is mitigated at a dosage range of 10-50 μg/ml, Diabetes is controlled within the same concentration. Wound healing is improved at concentrations of 10-50 μg/ml and with a typical range of 10-08 μg/ml for bacteria with antimicrobial capabilities. Advancement of silver nanoparticles with a focus on the future use of AgNPs-coated wound dressings and medical devices to decrease the risk of infection. Chemotherapeutic drugs can be administered by AgNPs, which reduces adverse effects and an improvement in treatment outcomes. AgNPs have been found to improve cell proliferation and differentiation, making them beneficial for tissue engineering and regenerative medicine. Our study highlights emerging patterns and developments in the field of medicine, inferring potential future paths.

Identifiants

pubmed: 39416696
doi: 10.1016/j.biotno.2024.05.002
pii: S2665-9069(24)00009-6
pmc: PMC11446369
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

64-79

Informations de copyright

© 2024 The Authors.

Déclaration de conflit d'intérêts

Author do not have any Conflict of Interest.

Auteurs

Karthik K Karunakar (K)

Department of Pharmacy Practice, Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences, Chennai, 602105, TN, India.

Binoy Varghese Cheriyan (BV)

Department of Pharmaceutical Chemistry, Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences, Chennai, 602105, TN, India.

Krithikeshvaran R (K)

Department of Pharmacy Practice, Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences, Chennai, 602105, TN, India.

Gnanisha M (G)

Department of Pharmacy Practice, Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences, Chennai, 602105, TN, India.

Abinavi B (A)

Department of Pharmacy Practice, Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences, Chennai, 602105, TN, India.

Classifications MeSH