In vivo imaging of the human brain with the Iseult 11.7-T MRI scanner.
Journal
Nature methods
ISSN: 1548-7105
Titre abrégé: Nat Methods
Pays: United States
ID NLM: 101215604
Informations de publication
Date de publication:
17 Oct 2024
17 Oct 2024
Historique:
received:
05
02
2024
accepted:
17
09
2024
medline:
18
10
2024
pubmed:
18
10
2024
entrez:
17
10
2024
Statut:
aheadofprint
Résumé
The understanding of the human brain is one of the main scientific challenges of the twenty-first century. In the early 2000s, the French Atomic Energy Commission launched a program to conceive and build a human magnetic resonance imaging scanner operating at 11.7 T. We have now acquired human brain images in vivo at such a magnetic field. We deployed parallel transmission tools to mitigate the radiofrequency field inhomogeneity problem and tame the specific absorption rate. The safety of human imaging at such high field strength was demonstrated using physiological, vestibular, behavioral and genotoxicity measurements on the imaged volunteers. Our technology yields T
Identifiants
pubmed: 39420141
doi: 10.1038/s41592-024-02472-7
pii: 10.1038/s41592-024-02472-7
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Agence Nationale de la Recherche (French National Research Agency)
ID : France 2030 Future Investment Program, ANR-21-ESRE-0006
Organisme : Agence Nationale de la Recherche (French National Research Agency)
ID : France 2030 Future Investment Program, ANR-21-ESRE-0006, ESR/EquipEx+, PRESENCE project
Organisme : Agence Nationale de la Recherche (French National Research Agency)
ID : France 2030 Future Investment Program, ANR-21-ESRE-0006, ESR/EquipEx+, PRESENCE project
Organisme : Agence Nationale de la Recherche (French National Research Agency)
ID : France 2030 Future Investment Program, ANR-21-ESRE-0006, ESR/EquipEx+, PRESENCE project
Organisme : Agence Nationale de la Recherche (French National Research Agency)
ID : France 2030 Future Investment Program, ANR-21-ESRE-0006, ESR/EquipEx+, PRESENCE project
Organisme : Agence Nationale de la Recherche (French National Research Agency)
ID : France 2030 Future Investment Program, ANR-21-ESRE-0006, ESR/EquipEx+, PRESENCE project
Organisme : Agence Nationale de la Recherche (French National Research Agency)
ID : France 2030 Future Investment Program, ANR-21-ESRE-0006, ESR/EquipEx+, PRESENCE project
Organisme : Agence Nationale de la Recherche (French National Research Agency)
ID : France 2030 Future Investment Program, ANR-21-ESRE-0006, ESR/EquipEx+, PRESENCE project
Organisme : Agence Nationale de la Recherche (French National Research Agency)
ID : France 2030 Future Investment Program, ANR-21-ESRE-0006, ESR/EquipEx+, PRESENCE project
Organisme : Agence Nationale de la Recherche (French National Research Agency)
ID : France 2030 Future Investment Program, ANR-21-ESRE-0006, ESR/EquipEx+, PRESENCE project
Organisme : EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 Future and Emerging Technologies (H2020 Excellent Science - Future and Emerging Technologies)
ID : AROMA FET Open 885876
Organisme : EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 Future and Emerging Technologies (H2020 Excellent Science - Future and Emerging Technologies)
ID : AROMA FET Open 885876
Organisme : EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 Future and Emerging Technologies (H2020 Excellent Science - Future and Emerging Technologies)
ID : AROMA FET Open 885876
Organisme : EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 Future and Emerging Technologies (H2020 Excellent Science - Future and Emerging Technologies)
ID : AROMA FET Open 885876
Organisme : EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 Future and Emerging Technologies (H2020 Excellent Science - Future and Emerging Technologies)
ID : AROMA FET Open 885876
Organisme : EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 Future and Emerging Technologies (H2020 Excellent Science - Future and Emerging Technologies)
ID : AROMA FET Open 885876
Informations de copyright
© 2024. The Author(s).
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