Integrating priorities at the intersection of cancer and neuroscience.

Journal

Cancer cell
ISSN: 1878-3686
Titre abrégé: Cancer Cell
Pays: United States
ID NLM: 101130617

Informations de publication

Date de publication:
15 Oct 2024
Historique:
received: 17 09 2024
revised: 17 09 2024
accepted: 23 09 2024
medline: 19 10 2024
pubmed: 19 10 2024
entrez: 18 10 2024
Statut: aheadofprint

Résumé

Cancer neuroscience is a rapidly growing multidisciplinary field that conceptualizes tumors as tissues fully integrated into the nervous system. Recognizing the complexity and challenges in this field is of fundamental importance to achieving the goal of translational impact for cancer patients. Our commentary highlights key scientific priorities, optimal training settings, and roadblocks to translating scientific findings to the clinic in this emerging field, aiming to formulate a transformative and cohesive path forward.

Identifiants

DOI: 10.1016/j.ccell.2024.09.014 PMID: 39423816
pubmed: 39423816
pii: S1535-6108(24)00362-3
doi: 10.1016/j.ccell.2024.09.014
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

Auteurs

William L Hwang (WL)

Center for Systems Biology, Center for Cancer Research, and Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA. Electronic address: whwang1@mgh.harvard.edu.

Ella N Perrault (EN)

Center for Systems Biology, Center for Cancer Research, and Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA; Program in Neuroscience, Department of Neurobiology, Harvard Medical School, Boston, MA, USA.

Alexander Birbrair (A)

Department of Dermatology, Carbone Cancer Center, and Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI, USA.

Brandi J Mattson (BJ)

The Belfer Neurodegeneration Consortium, Therapeutics Discovery Division, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

David H Gutmann (DH)

Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.

Donald J Mabbott (DJ)

Neurosciences and Mental Health Program, Research Institute, Hospital for Sick Children, Toronto, ON, Canada.

Edna Cukierman (E)

Fox Chase Cancer Center, Temple Health, Philadelphia, PA, USA; Tumor Microenvironment Working Group, American Association for Cancer Research, Philadelphia, PA, USA.

Elizabeth A Repasky (EA)

Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.

Erica K Sloan (EK)

Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, VIC, Australia.

Hui Zong (H)

Department of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, VA, USA.

Ihsan Ekin Demir (IE)

Department of Surgery, TUM University Hospital, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; Else Kröner Clinician Scientist Professor, Munich, Germany.

Jami L Saloman (JL)

Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Department of Neurobiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

Jeremy C Borniger (JC)

Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.

Jian Hu (J)

Department of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Jorg Dietrich (J)

Department of Neurology, Center for Neuro-Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Joshua J Breunig (JJ)

Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Kaan Çifcibaşı (K)

Department of Surgery, TUM University Hospital, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

Khalil Ali Ahmad Kasm (KA)

Department of Symptom Research, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Manuel Valiente (M)

Brain Metastasis Group, CNIO, Madrid, Spain.

Max Wintermark (M)

Department of Neuroradiology, MD Anderson Cancer Center, Houston, TX, USA.

Munjal M Acharya (MM)

Department of Anatomy and Neurobiology, University of California at Irvine, Irvine, CA, USA.

Nicole N Scheff (NN)

Department of Neurobiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

Nisha J D'Silva (NJ)

Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.

Paola D Vermeer (PD)

Cancer Biology and Immunotherapies Group, Sanford Research, Sioux Falls, SD, USA.

Richard J Wong (RJ)

Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Sebastien Talbot (S)

Department of Physiology and Pharmacology, Karolinska Institute, Solna, Sweden; Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.

Shawn L Hervey-Jumper (SL)

Department of Neurosurgery and Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.

Timothy C Wang (TC)

Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.

Yi Ye (Y)

Translational Research Center, Pain Research Center, Department of Molecular Pathobiology, New York University College of Dentistry, New York, NY, USA.

Yuan Pan (Y)

Department of Symptom Research, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Yuri L Bunimovich (YL)

Department of Dermatology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Moran Amit (M)

Department of Head and Neck Surgery and the Department of Genomic Medicine, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA; University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA. Electronic address: mamit@mdanderson.org.

Classifications MeSH